The New Anatomy of Neuroimmunology

Autor: Claudio Solaro, David Barratt, Mauro Vaccarezza

In the past few years, a renowned interest in the interplay between the immune system and central nervous systems (CNS) has sparked a wealth of new experimental studies. Two recent publications in Science shed new light on the “resident” immune c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99a2634f9a8a1cbbac64d87913f2ce2
https://hdl.handle.net/11392/2491193

Mechanical ventilation and COPD: from pathophysiology to ventilatory management

Autor: Gaetano SCARAMUZZO, Irene OTTAVIANI, Carlo A. VOLTA, Savino SPADARO

In the chronic obstructive pulmonary disease (COPD), lung and chest-wall morphological alterations determine important and peculiar approaches to mechanical ventilation. Lung emphysema and reduced elastic recoil increase expiratory time, thus worseni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32c587d46fae7e21467056f48b37af6
http://hdl.handle.net/11392/2491974

Phytotherapy for menopausal symptoms: Recommendations of the italian menopause society (SIM) and the Italian society of gynaecology for the third age (SIGiTE)

Autor: Cagnacci A., Volpe A., Di Carlo C., De Leo V., Bifulco G., Gambacciani M., Alfieri S., Biglia N., Bonaccorsi G., Caruso S., Cicinelli E., De Franciscis P., Gambera A., Grasso A., Murina F., Paoletti A. M., Vicariotto F., Villa P., Gallo M., Nocera F., Maffei S., Pandolfo M., Lello S., Ambroggio S., Capozzi A., Grassi G., Rossi R., Stomatis M., Becorpi A., Forte A., Azzena A., Costantino D., Del Pup L., Mapelli M.

Evidence on the efficacy of phythotherapic remedies for the treatment of menopausal symptoms were reviewed. Evidence of the literature were graded and level of reccomandation defined. A strenght A recommendation was given for isaproponol extract of C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e65db090f82d8d6335a5f9a81a5dde5
https://hdl.handle.net/11392/2496732

Biallelic variants in LIG3 cause a novel mitochondrial neurogastrointestinal encephalomyopathy

Autor: Pierluigi Martelli, Tom J. de Koning, Takema Kato, Irene Liparulo, Mariko Taniguchi-Ikeda, Tatsushi Toda, Hisayoshi Nakamura, Wilfred F. A. den Dunnen, Giovanna Cenacchi, Sanjiban Chakrabarty, Yu Sheng Yeh, Sushil Kumar Mishra, Rita Casadio, Akira Ohtake, Ichizo Nishino, Roberto De Giorgio, Paolo Picco, Pasquale Striano, Chiara Fiorillo, Isabella Ceccherini, Tsuyoshi Goto, Elisa Boschetti, Makiko Tsutsumi, Eleonora Aronica, Georgios Kellaris, Mariel Alders, Gabor E. Linthorst, Jantima Tanboon, Angela Rita Sementa, Floor A. M. Duijkers, Yu Ichi Goto, Hiroki Kurahashi, Masakazu Mimaki, Gerard Dijkstra, Dik C. van Gent, Mariasavina Severino, Yoshinobu Oyazato, Christian Bergamini, Ikuya Nonaka, Yoshiki Yamaguchi, Ivana Matera, Giuseppe Raiola, Karin Van Spaendonck, Nicholas Katsanis, Luca Masin, Shumpei Uchino, Kenjiro Kosaki, Sara Signa, Anja Raams, Federica Isidori, Elena Bonora, Serena Arrigo, Kandai Nozu, Marc Engelen, Farid Ullah, Ichiro Morioka, Chiara Diquigiovanni, Marco Seri, Valerio Carelli, Francesca Bianco, Mariapia Giuditta Cratere, Nicola Rizzardi, Romana Fato, Alessandra Maresca, Alyson W. MacInnes, Valentina Papa, Kazumoto Iijima

Publikováno v: Brain : a Journal of Neurology, 144(5), 1451-1466. Oxford University Press
Brain, 144(5), 1451-1466. Oxford University Press

Abnormal gut motility is a feature of several mitochondrial encephalomyopathies, and mutations in genes such as TYMP and POLG, have been linked to these rare diseases. The human genome encodes three DNA ligases, of which only one, ligase III (LIG3),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e470f830e056717e954489f79a11efb4
http://hdl.handle.net/11567/1065221

Polyamine Oxidase Is Involved in Spermidine Reduction of Transglutaminase Type 2-Catalyzed βH-Crystallins Polymerization in Calcium-Induced Experimental Cataract

Autor: Carlo Mischiati, Sonia Melino, Claudio Tabolacci, Cinzia Forni, Simone Beninati, Giordana Feriotto, Ilaria Borromeo, Fabio Domenici, Angelo Martino

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 15
International Journal of Molecular Sciences, Vol 21, Iss 5427, p 5427 (2020)

In an in vitro Ca2+-induced cataract model, the progression of opacification is paralleled by a rapid decrease of the endogenous levels of spermidine (SPD) and an increase of transglutaminase type 2 (TG2, EC 2.3.2.13)-catalyzed lens crystallins cross

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61622ff911f37349550190c247e5d034
https://doi.org/10.3390/ijms21155427