Výsledky vyhledávání - "LOX, Lysyl oxidase"

Publikováno v: Tsuchiya, Hiroyuki. Shiota, Goshi. Immune evasion by cancer stem cells. Regenerative Therapy. 17. 20-33. doi:10.1016/j.reth.2021.02.006
Regenerative Therapy, Vol 17, Iss, Pp 20-33 (2021)
Regenerative Therapy

Tumor immunity represents a new avenue for cancer therapy. Immune checkpoint inhibitors have successfully improved outcomes in several tumor types. In addition, currently, immune cell-based therapy is also attracting significant attention. However, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6054a82a446a6f8b0b1100401e59a6
https://doi.org/10.1016/j.reth.2021.02.006

Zobrazit plný text záznamu

The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties

Autor: Karan M. Shah, Elena Adinolfi, Elena De Marchi, Archana Singh, Luke Tattersall, Alex Williamson, Jennifer M. Down, William D. Fraser, Alison Gartland, Francesco Di Virgilio, Michelle A. Lawson, Dominique Heymann, Darren Lath, Darrell Green

Publikováno v: Journal of Bone Oncology
Journal of Bone Oncology, 2021, 31, pp.100398. ⟨10.1016/j.jbo.2021.100398⟩
Journal of Bone Oncology, Vol 31, Iss, Pp 100398-(2021)

Osteosarcoma (OS) is the most common type of primary bone cancer affecting children and adolescents. OS has a high propensity to spread, meaning the disease is often incurable and fatal. There have been no improvements in survival rates for decades.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b702ba5c427745d1727816023f8ed9a8
https://eprints.whiterose.ac.uk/179999/1/1-s2.0-S2212137421000531-main.pdf

Zobrazit plný text záznamu

Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma

Autor: Weiying Zhang, Xueli Fu, Bowen Liu, Lu Zhang, Lihong Ye, Xue Wang, Tianjiao Wang, Kai Ye, Feifei Xu, Tianzhi Jin, Yue Wu

Publikováno v: EBioMedicine

Background Abnormal construction of the extracellular matrix (ECM) is intimately linked with carcinogenesis and the development of solid tumours, especially hepatocellular carcinoma (HCC). As the major component of the ECM, collagen plays a pivotal r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57215d87506c1b3fb9365ffcf333d32
http://europepmc.org/articles/PMC6642319

Zobrazit plný text záznamu

Deletion of

Autor: Michael P, Murphy, Justin R, King, Katherin E, Leckie

Publikováno v: JACC: Basic to Translational Science

Visual Abstract
Highlights • Stat3, a major signaling molecule for proinflammatory cytokines including IL-6, was activated both in inflammatory cells and in SMC in the aortic walls of human AD and mouse AD model. • SMC-specific deletion of S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::97e00503172b3927b073b90216d64ddb
https://pubmed.ncbi.nlm.nih.gov/32140621

Zobrazit plný text záznamu

Paracrine and cell autonomous signalling in pancreatic cancer progression and metastasis

Autor: Stacy K. Thomas, Gregory L. Beatty, Jesse Lee

Publikováno v: EBioMedicine
EBioMedicine, Vol 53, Iss, Pp-(2020)

Pancreatic ductal adenocarcinoma (PDAC) shows remarkable propensity to metastasize. This predilection to escape from the primary tumor is driven by paracrine and autocrine mechanisms that guide cancer cells through a multi-step process concluding wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f38a4705938724fb049d0b00dcf2eb2
http://europepmc.org/articles/PMC7118576

Zobrazit plný text záznamu

Mix and (mis-)match – The mechanosensing machinery in the changing environment of the developing, healthy adult and diseased heart☆

Autor: Ward, Matthew, Iskratsch, Thomas

Publikováno v: Biochimica et Biophysica Acta. Molecular Cell Research

The composition and the stiffness of cardiac microenvironment change during development and/or in heart disease. Cardiomyocytes (CMs) and their progenitors sense these changes, which decides over the cell fate and can trigger CM (progenitor) prolifer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4179d4eefebf105245222732b8cb9ce5
http://europepmc.org/articles/PMC7042712

Zobrazit plný text záznamu

A comparative study of the elastic fibre system within the mouse and human cornea

Autor: Feneck, Eleanor M., Lewis, Philip N., Ralphs, Jim, Meek, Keith M.

Publikováno v: Experimental Eye Research

The cornea relies on its organised extracellular matrix for maintaining transparency and biomechanical strength. Studies have identified an elastic fibre system within the human posterior cornea, thought to allow for slight deformations in response t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5762b0ae6738deb97794f9b6bc0a7ba3
http://europepmc.org/articles/PMC6280038

Zobrazit plný text záznamu

Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini Review

Autor: Jessica Bauer, Yasna Jain, Taher A. Saif, Barbara Jung, Bashar Emon

Publikováno v: Computational and Structural Biotechnology Journal, Vol 16, Iss, Pp 279-287 (2018)
Computational and Structural Biotechnology Journal

The role of tumor microenvironment in cancer progression is gaining significant attention. It is realized that cancer cells and the corresponding stroma co-evolve with time. Cancer cells recruit and transform the stromal cells, which in turn remodel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f502b279b62334028d536320270ae9
https://doi.org/10.1016/j.csbj.2018.07.003

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání