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of 367
pro vyhledávání: '"LOTKE, P."'
Autor:
Jennifer L. Zack, Shawnika J. Hull, Megan E. Coleman, Peggy Peng Ye, Pamela S. Lotke, Adam Visconti, Jason Beverley, Ashley Brant, Patricia Moriarty, Rachel K. Scott
Publikováno v:
Therapeutic Advances in Infectious Disease, Vol 11 (2024)
Background: Pre-exposure prophylaxis (PrEP) utilization among cisgender women (subsequently ‘women’) is low across age groups, relative to their risk of HIV acquisition. We hypothesize that age-related differences in psychosocial factors also inf
Externí odkaz:
https://doaj.org/article/f1391afdbdc54af29f21329f6eacd323
Autor:
Luca Schelle, João Vasco Côrte-Real, Sharmeen Fayyaz, Augusto del Pozo Ben, Margarita Shnipova, Moritz Petersen, Rishikesh Lotke, Bhavna Menon, Dana Matzek, Lena Pfaff, Ana Pinheiro, João Pedro Marques, José Melo-Ferreira, Bastian Popper, Pedro José Esteves, Daniel Sauter, Joana Abrantes, Hanna-Mari Baldauf
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Guanylate binding proteins (GBPs) are an evolutionarily ancient family of proteins that are widely distributed among eukaryotes. They belong to the dynamin superfamily of GTPases, and their expression can be partially induced by interferons (IFNs). G
Externí odkaz:
https://doaj.org/article/f9eaed9ec78849db87f66e1c42b9f5e4
Autor:
Sudhanshu Vaibhav Lotke, Arvinder Pal Singh Narula, Jayashree Sachin Gothankar, Prasad Dyandeo Pore, Rupeshkumar Balasaheb Deshmukh, Prakash Prabhakarrao Doke
Publikováno v:
MGM Journal of Medical Sciences, Vol 10, Iss 2, Pp 257-263 (2023)
Background: Family planning services have been given importance for decades. For various reasons, sterilization has been the first choice of women and the government. It is feared that while achieving large numbers, the quality may be compromised. Th
Externí odkaz:
https://doaj.org/article/9fe0369043444bc5994ed2b2fefebb9e
Publikováno v:
Viruses, Vol 16, Iss 3, p 332 (2024)
The human genome is estimated to encode more than 500 proteases performing a wide range of important physiological functions. They digest proteins in our food, determine the activity of hormones, induce cell death and regulate blood clotting, for exa
Externí odkaz:
https://doaj.org/article/a8fee4e7fa96490ca011c066d881033e
Autor:
Elena Hagelauer, Rishikesh Lotke, Dorota Kmiec, Dan Hu, Mirjam Hohner, Sophie Stopper, Rayhane Nchioua, Frank Kirchhoff, Daniel Sauter, Michael Schindler
Publikováno v:
Viruses, Vol 15, Iss 12, p 2364 (2023)
Coronavirus infection induces interferon-stimulated genes, one of which encodes Tetherin, a transmembrane protein inhibiting the release of various enveloped viruses from infected cells. Previous studies revealed that SARS-CoV encodes two Tetherin an
Externí odkaz:
https://doaj.org/article/b5738df78ffd4aacb0d19d3299f76caf
Akademický článek
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Autor:
Marianne Boutin, Halima Medjahed, Manon Nayrac, Rishikesh Lotke, Gabrielle Gendron-Lepage, Catherine Bourassa, Daniel Sauter, Jonathan Richard, Andrés Finzi
Publikováno v:
Viruses, Vol 15, Iss 5, p 1189 (2023)
HIV-1 envelope glycoproteins (Envs) mediate viral entry and represent a target of choice for small molecule inhibitors. One of them, temsavir (BMS-626529) prevents the interaction of the host cell receptor CD4 with Env by binding the pocket under the
Externí odkaz:
https://doaj.org/article/831999be44ab48378cc10eb963e3ab2a
Akademický článek
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Akademický článek
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Autor:
Zhe Zhao, Riku Fagerlund, Helena Tossavainen, Kristina Hopfensperger, Rishikesh Lotke, Smitha Srinivasachar Badarinarayan, Frank Kirchhoff, Perttu Permi, Kei Sato, Daniel Sauter, Kalle Saksela
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1009728 (2021)
The accessory protein Nef of human and simian immunodeficiency viruses (HIV and SIV) is an important pathogenicity factor known to interact with cellular protein kinases and other signaling proteins. A canonical SH3 domain binding motif in Nef is req
Externí odkaz:
https://doaj.org/article/1318f37ecbe84d2aabcfcf4234f5b6b8