Acrylamide induces a thyroid allostasis–adaptive response in prepubertal exposed rats

Autor: Isabela Medeiros de Oliveira, Dalton Luiz Schiessel, Fernanda Ivanski, Viviane Matoso de Oliveira, Paula Bargi-Souza, Marco Romano, Renata Marino Romano

Publikováno v: Current Research in Toxicology
Current Research in Toxicology, Vol 1, Iss, Pp 124-132 (2020)

Graphical abstract
Highlights • Acrylamide acts as endocrine disruptor for the thyroid gland function. • Acrylamide increases the transcript expression of proteins related to THs synthesis. • Exposure to acrylamide alters the hypothalamus-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ade5a1f87923921749581ed3e26df6
http://europepmc.org/articles/PMC8320623

Using data from food challenges to inform management of consumers with food allergy: A systematic review with individual participant data meta-analysis

Autor: Daniel C. Adelman, Joseph L. Baumert, W. Marty Blom, Ross A.R. Yarham, E. N. Clare Mills, R. Sharon Chinthrajah, Hugh A. Sampson, Bushra Javed, Nandinee Patel, Katherine Anagnostou, Paul Turner, Benjamin C. Remington, Alexander D. Smith, Natasha Purington, Dianne E. Campbell

Publikováno v: The Journal of Allergy and Clinical Immunology
Patel, N, Adelman, D C, Anagnostou, K, Baumert, J L, Blom, W M, Campbell, D E, Chinthrajah, R S, Mills, E N C, Javed, B, Purington, N, Remington, B C, Sampson, H A, Smith, A D, Yarham, R A R & Turner, P J 2021, ' Using data from food challenges to inform management of consumers with food allergy : A systematic review with individual participant data meta-analysis ', The Journal of allergy and clinical immunology, vol. 147, no. 6, pp. 2249-2262 . https://doi.org/10.1016/j.jaci.2021.01.025

Background Eliciting doses (EDs) (eg, ED01 or ED05 values, which are the amounts of allergen expected to cause objective symptoms in 1% and 5% of the population with an allergy, respectively) are increasingly being used to inform allergen labeling an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8b1b803df04a4bb11cc67502099f3b
https://doi.org/10.1016/j.jaci.2021.01.025

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COSMOS next generation - A public knowledge base leveraging chemical and biological data to support the regulatory assessment of chemicals.

Autor: Yang C; MN-AM, Columbus, OH, USA.; MN-AM Nürnberg, Germany., Cronin MTD; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Arvidson KB; US FDA CFSAN College Park, MD, USA., Bienfait B; MN-AM Nürnberg, Germany., Enoch SJ; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Heldreth B; Cosmetic Ingredient Review, Washington, DC, USA., Hobocienski B; MN-AM, Columbus, OH, USA., Muldoon-Jacobs K; US FDA CFSAN College Park, MD, USA., Lan Y; University of Bradford, UK., Madden JC; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Magdziarz T; MN-AM Nürnberg, Germany., Marusczyk J; MN-AM Nürnberg, Germany., Mostrag A; MN-AM, Columbus, OH, USA., Nelms M; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Neagu D; University of Bradford, UK., Przybylak K; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Rathman JF; MN-AM, Columbus, OH, USA.; The Ohio State University, Columbus OH, USA., Park J; MN-AM, Columbus, OH, USA., Richarz AN; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Richard AM; US EPA RTP, NC, USA., Ribeiro JV; MN-AM, Columbus, OH, USA., Sacher O; MN-AM Nürnberg, Germany., Schwab C; MN-AM Nürnberg, Germany., Vitcheva V; MN-AM, Columbus, OH, USA.; MN-AM Nürnberg, Germany., Volarath P; US FDA CFSAN College Park, MD, USA., Worth AP; European Commission, Joint Research Centre (JRC), Ispra, Italy.

Publikováno v: Computational toxicology (Amsterdam, Netherlands) [Comput Toxicol] 2021 Aug; Vol. 19, pp. 100175.

Acrylamide induces a thyroid allostasis-adaptive response in prepubertal exposed rats.

Autor: Oliveira VM; Laboratory of Reproductive Toxicology, Department of Medicine, State University of Central-West, Rua Simeao Camargo Varela de Sa, 03, 85040-080 Parana, Brazil., Ivanski F; Laboratory of Reproductive Toxicology, Department of Medicine, State University of Central-West, Rua Simeao Camargo Varela de Sa, 03, 85040-080 Parana, Brazil., Oliveira IM; Laboratory of Reproductive Toxicology, Department of Medicine, State University of Central-West, Rua Simeao Camargo Varela de Sa, 03, 85040-080 Parana, Brazil., Bargi-Souza P; Department of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais, Avenida Presidente Antônio Carlos, 6627, 31270-901 Minas Gerais, Brazil., Schiessel DL; Department of Nutrition, State University of Central-West, Rua Simeao Camargo Varela de Sa, 03, 85040-080 Parana, Brazil., Romano MA; Laboratory of Reproductive Toxicology, Department of Medicine, State University of Central-West, Rua Simeao Camargo Varela de Sa, 03, 85040-080 Parana, Brazil., Romano RM; Laboratory of Reproductive Toxicology, Department of Medicine, State University of Central-West, Rua Simeao Camargo Varela de Sa, 03, 85040-080 Parana, Brazil.

Publikováno v: Current research in toxicology [Curr Res Toxicol] 2020 Oct 31; Vol. 1, pp. 124-132. Date of Electronic Publication: 2020 Oct 31 (Print Publication: 2020).