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Autor:
Nitya G. Kundu, Jyan S. Mahanty, C. P. Spears, Swapan K. Dasgupta, LN Chaudhuri, A.H. Shahinian
Publikováno v:
European Journal of Medicinal Chemistry. 28:473-479
The synthesis of a number of 5-substituted uracils, eg [ E ]-5-(2-acylvinyl)uracils 8a–8g is described. These compounds were found to have cytotoxic activities against CCRF-CEM human lymphoblastoid cells, HT-29 colon carcinoma cells and L1210/0 mou