Zobrazeno 1 - 10
of 271
pro vyhledávání: '"LMX1A"'
Autor:
Kirstin O. McDonald, Nikita M. A. Lyons, Luca K. C. Gray, Janet B. Xu, Lucia Schoderboeck, Stephanie M. Hughes, Indranil Basak
Publikováno v:
Cells, Vol 13, Iss 12, p 1016 (2024)
Dopaminergic neurons are the predominant brain cells affected in Parkinson’s disease. With the limited availability of live human brain dopaminergic neurons to study pathological mechanisms of Parkinson’s disease, dopaminergic neurons have been g
Externí odkaz:
https://doaj.org/article/9dd4689e35f045f190896ade8ce2164e
Akademický článek
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Akademický článek
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Publikováno v:
Open Medicine, Vol 16, Iss 1, Pp 224-236 (2021)
Previous work has shown that miR-142-5p in cervical cancer tissues increased significantly compared with adjacent normal tissues. However, the function and the mechanism of miR-142-5p in cervical cancer have not been reported.
Externí odkaz:
https://doaj.org/article/e7dfa6979b1c47dea96707298cdbe3e4
Autor:
Haakon R. Hol, Marianne M. Flak, Linda Chang, Gro Christine Christensen Løhaugen, Knut Jørgen Bjuland, Lars M. Rimol, Andreas Engvig, Jon Skranes, Thomas Ernst, Bengt-Ove Madsen, Susanne S. Hernes
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
BackgroundAdaptive computerized working memory (WM) training has shown favorable effects on cerebral cortical thickness as compared to non-adaptive training in healthy individuals. However, knowledge of WM training-related morphological changes in mi
Externí odkaz:
https://doaj.org/article/6f60dda246bb49e0b9ea60d74e201418
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2125 (2022)
Sensorineural hearing loss is one of the most common inherited sensory disorders. Functional classifications of deafness genes have shed light on genotype- and mechanism-based pharmacological approaches and on gene therapy strategies. In this study,
Externí odkaz:
https://doaj.org/article/87b81e6f97044dd1bc4973601b69e155
Autor:
Salvatore Pulcrano, Roberto De Gregorio, Claudia De Sanctis, Laura Lahti, Carla Perrone-Capano, Donatella Ponti, Umberto di Porzio, Thomas Perlmann, Massimiliano Caiazzo, Floriana Volpicelli, Gian Carlo Bellenchi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 6961 (2022)
The development of midbrain dopaminergic (DA) neurons requires a fine temporal and spatial regulation of a very specific gene expression program. Here, we report that during mouse brain development, the microRNA (miR-) 204/211 is present at a high le
Externí odkaz:
https://doaj.org/article/2e6e1d43887349c980e46c0a694c29c2
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Externí odkaz:
https://doaj.org/article/dcc996a4ccf84c4fb5042b07716e38b8
Autor:
Susanne S. Hernes, Marianne M. Flak, Gro C. C. Løhaugen, Jon Skranes, Haakon R. Hol, Bengt-Ove Madsen, Anne-Brita Knapskog, Andreas Engvig, Are Pripp, Ingun Ulstein, Trine Lona, Xin Zhang, Linda Chang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Working memory training (WMT) effects may be modulated by mild cognitive impairment (MCI) subtypes, and variations in APOE-epsilon (APOE-ε) and LMX1A genotypes. Sixty-one individuals (41 men/20 women, mean age 66 years) diagnosed with MCI (31 amnest
Externí odkaz:
https://doaj.org/article/29e1811af37f48ddbc4c8cae3556e12e
Single-Cell RNA Analysis of Type I Spiral Ganglion Neurons Reveals a Lmx1a Population in the Cochlea
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
In the mature cochlea, each inner hair cell (IHC) is innervated by multiple spiral ganglion neurons of type I (SGNI). SGNIs are morphologically and electro-physiologically diverse. Also, they differ in their susceptibility to noise insult. However, t
Externí odkaz:
https://doaj.org/article/baffeb221fae45789c09cb2880f97cb4