LLGL1 Regulates Gemcitabine Resistance by Modulating the ERK-SP1-OSMR Pathway in Pancreatic Ductal AdenocarcinomaSummary

Autor: Yangchao Chen, Tian Xia, Guolin Li, Frederic Khe Cheong Fung, Ka Fai To, Joanna H.M. Tong, Chi Han Li, Yin-Xin Zhu, Chi Hin Wong, Huiyi Feng, Rufu Chen

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 4, Pp 811-828 (2020)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Gemcitabine resistance is rapidly acquired by pancreatic ductal adenocarcinoma (PDAC) patients. Novel approaches that predict the gemcitabine response of patients and enhance gemcitabine chemosensitivity are important to improve pat

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http://www.sciencedirect.com/science/article/pii/S2352345X20300989