Zobrazeno 1 - 10
of 17
pro vyhledávání: '"LLC, Lewis lung carcinoma"'
Autor:
Mingxiao Yin, Xiaojia Liu, Na Zhang, Genxiang Mao, Lu Liu, Hongbin Deng, Peng Yang, Wenjian Min, Kuang Ze'an, Jingwen Dong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3134-3149 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Programmed cell death ligand 1 (PD-L1)/programmed cell death protein 1 (PD-1) cascade is an effective therapeutic target for immune checkpoint blockade (ICB) therapy. Targeting PD-L1/PD-1 axis by small-molecule drug is an attractive approach to enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d344df92d314f733377ab3c9584020
http://www.sciencedirect.com/science/article/pii/S2211383521001118
http://www.sciencedirect.com/science/article/pii/S2211383521001118
Publikováno v:
Neoplasia (New York, N.Y.)
Early lung carcinoma development may be modulated by innate host cellular mechanisms that promote tumor growth and invasion. We recently identified how a loss-of-function mutation in the glycan sulfating enzyme N-deacetylase/N-sulfotransferase-1 (Nds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c1a8c4e83557920ae120f81f6685b95
http://europepmc.org/articles/PMC8560828
http://europepmc.org/articles/PMC8560828
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 2, Pp 86-97 (2020)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.), vol 22, iss 2
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.), vol 22, iss 2
While recent research points to the importance of glycans in cancer immunity, knowledge on functional mechanisms is lacking. In lung carcinoma among other tumors, anti-tumor immunity is suppressed; and while some recent therapies boost T-cell mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7e0acb8a762ad1ad8ad75a631c6062
http://www.sciencedirect.com/science/article/pii/S1476558619303045
http://www.sciencedirect.com/science/article/pii/S1476558619303045
Publikováno v:
Translational Oncology, Vol 17, Iss, Pp 101341-(2022)
Translational Oncology
Translational Oncology
Highlights • Thioredoxin reductase (TrxR), a seleno enzyme, regulates cellular redox. • Several human cancers are known to overexpress TrxR. • Inhibitors of TrxR have enhanced radiation induced cytotoxicity in multiple cancers. • TrxR could b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aaf62bdf3583fc4416746fca6cdfb01
http://www.sciencedirect.com/science/article/pii/S1936523322000031
http://www.sciencedirect.com/science/article/pii/S1936523322000031
Publikováno v:
Pharmacological Research
Graphical abstract Molecular targets modulated by artemisinins in respiratory diseases.
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184b9b3d7b7767e97cb84ac3227c7da4
Autor:
Iwata, Yuko, Suzuki, Nobuyuki, Ohtake, Hitomi, Kamauchi, Shinya, Hashimoto, Naohiro, Kiyono, Tohru, Wakabayashi, Shigeo
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Background Muscle wasting during cancer cachexia contributes to patient morbidity. Cachexia‐induced muscle damage may be understood by comparing its symptoms with those of other skeletal muscle diseases, but currently available data are limited. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45a5534e5f7da8aa42888debcc8d554e
http://europepmc.org/articles/PMC4864294
http://europepmc.org/articles/PMC4864294
Autor:
Yoshihito Nakatani, Yukio Ishikawa, Toshiharu Ishii, Ichiro Kudo, Yuka Sasaki, Daisuke Kamei, Shizuo Akira, Masataka Majima, Makoto Murakami, Satoshi Uematsu, Shuntaro Hara
Publikováno v:
Biochemical Journal
mPGES-1 (microsomal prostaglandin E synthase-1) is a stimulus-inducible enzyme that functions downstream of COX (cyclo-oxygenase)-2 in the PGE2 (prostaglandin E2)-biosynthesis pathway. Although COX-2-derived PGE2 is known to play a role in the develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17581e12000bb7359979f2294958145
http://europepmc.org/articles/PMC2825730
http://europepmc.org/articles/PMC2825730
Publikováno v:
Известия высших учебных заведений. Поволжский регион. Медицинские науки.
Изучена противоопухолевая и антиметастатическая эффективность дикарбамина и циклофосфана на сингенной опухолевой системе карциноме
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2806::92de7eb805be92ec63dfee85e643ff01
http://cyberleninka.ru/article/n/izuchenie-vliyaniya-dikarbamina-na-effektivnost-tsitostaticheskoy-terapii-u-myshey-s-kartsinomoy-legkih-lyuis
http://cyberleninka.ru/article/n/izuchenie-vliyaniya-dikarbamina-na-effektivnost-tsitostaticheskoy-terapii-u-myshey-s-kartsinomoy-legkih-lyuis
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