Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease

Autor: Sim, Lesley, C Quek, Li, Xia, SA Bellingham, LJ Ellett, Shambrook, Mitch, S Zafar, I Zerr, VA Lawson, Hill, Andrew

Prion diseases are distinguished by long pre-clinical incubation periods during which prions actively propagate in the brain and cause neurodegeneration. In the pre-clinical stage, we hypothesize that upon prion infection, transcriptional changes occ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0773a2ea7e8557c537fd66943ded12c6

Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease.

Autor: Cheng L; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC, Australia. l.cheng@latrobe.edu.au.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia. l.cheng@latrobe.edu.au., Quek C; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia., Li X; Department of Mathematics and Statistics, La Trobe University, Bundoora, VIC, Australia., Bellingham SA; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia., Ellett LJ; Department of Pathology, The University of Melbourne, Melbourne, VIC, Australia.; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia.; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia., Shambrook M; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC, Australia.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia., Zafar S; Department of Neurology, University Medical Center Göttingen and German Center for Neurodegenerative Diseases, Göttingen, Germany.; Biomedical Engineering and Sciences Department, School of Mechanical and Manufacturing Engineering (SMME), National University of Sciences and Technology (NUST), Islamabad, Pakistan., Zerr I; Department of Neurology, University Medical Center Göttingen and German Center for Neurodegenerative Diseases, Göttingen, Germany., Lawson VA; Department of Pathology, The University of Melbourne, Melbourne, VIC, Australia.; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia.; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia., Hill AF; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC, Australia. andrew.hill@latrobe.edu.au.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia. andrew.hill@latrobe.edu.au.

Publikováno v: Communications biology [Commun Biol] 2021 Mar 25; Vol. 4 (1), pp. 411. Date of Electronic Publication: 2021 Mar 25.

Chronic isolation stress is associated with increased colonic and motor symptoms in the A53T mouse model of Parkinson's disease.

Autor: Diwakarla S; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic., Australia.; Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Vic., Australia., Finkelstein DI; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic., Australia., Constable R; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic., Australia., Artaiz O; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic., Australia., Di Natale M; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic., Australia., McQuade RM; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic., Australia.; Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Vic., Australia., Lei E; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic., Australia., Chai XY; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic., Australia., Ringuet MT; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic., Australia.; Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Vic., Australia., Fothergill LJ; Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Vic., Australia., Lawson VA; The Department of Pathology, University of Melbourne, Parkville, Vic., Australia., Ellett LJ; The Department of Pathology, University of Melbourne, Parkville, Vic., Australia., Berger JP; Takeda Pharmaceuticals International, Inc, Cambridge, MA, USA., Furness JB; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic., Australia.; Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Vic., Australia.

Publikováno v: Neurogastroenterology and motility [Neurogastroenterol Motil] 2020 Mar; Vol. 32 (3), pp. e13755. Date of Electronic Publication: 2019 Nov 10.

Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc.

Autor: Foliaki ST; Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Parkville, Victoria, Australia., Lewis V; Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Parkville, Victoria, Australia.; Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia., Islam AMT; Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Parkville, Victoria, Australia., Ellett LJ; Department of Pathology The University of Melbourne, Parkville, Victoria, Australia.; Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia., Senesi M; Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Parkville, Victoria, Australia., Finkelstein DI; Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia., Roberts B; Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia., Lawson VA; Department of Pathology The University of Melbourne, Parkville, Victoria, Australia.; Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia., Adlard PA; Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia., Collins SJ; Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Parkville, Victoria, Australia.; Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia.

Publikováno v: PLoS pathogens [PLoS Pathog] 2019 Apr 10; Vol. 15 (4), pp. e1007712. Date of Electronic Publication: 2019 Apr 10 (Print Publication: 2019).

Method for Folding of Recombinant Prion Protein to Soluble β-Sheet Secondary Structure.

Autor: Ellett LJ; Department of Pathology, The University of Melbourne, Parkville, VIC, 3010, Australia. lellett@unimelb.edu.au.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2017; Vol. 1658, pp. 23-26.