Zobrazeno 1 - 10
of 14
pro vyhledávání: '"LISA KOSHKO"'
Intrinsic sexual dimorphism in the placenta determines the differential response to benzene exposure
Autor:
Anthony Maxwell, Nicholas Adzibolosu, Anna Hu, Yuan You, Paul M. Stemmer, Douglas M. Ruden, Michael C. Petriello, Marianna Sadagurski, Lucas K. Debarba, Lisa Koshko, Jayanth Ramadoss, Annie Thy Nguyen, Darby Richards, Aihua Liao, Gil Mor, Jiahui Ding
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106287- (2023)
Summary: Maternal immune activation (MIA) by environmental challenges is linked to severe developmental complications, such as neurocognitive disorders, autism, and even fetal/maternal death. Benzene is a major toxic compound in air pollution that af
Externí odkaz:
https://doaj.org/article/07b2399baee443fd90afa6f11e1f4297
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Environmental contaminants in ambient air pollution pose a serious risk to long-term metabolic health. Strong evidence shows that prenatal exposure to pollutants can significantly increase the risk of Type II Diabetes (T2DM) in children and all ethni
Externí odkaz:
https://doaj.org/article/9f1015e2707548a3b3cbc205849e8a1c
Autor:
Lukas Stilgenbauer, Juliana Bezerra Medeiros de Lima, Lucas Kniess Debarba, Manal Khan, Lisa Koshko, John J. Kopchick, Andrzej Bartke, Augusto Schneider, Marianna Sadagurski
Publikováno v:
GeroScience.
Autor:
Lisa Koshko, Sydney Scofield, Lucas Debarba, Lukas Stilgenbauer, Mikaela Sacla, Patrick Fakhoury, Hashan Jayarathne, J. Eduardo Perez-Mojica, Ellen Griggs, Adelheid Lempradl, Marianna Sadagurski
Publikováno v:
bioRxiv
The hypothalamus is essential in the regulation of metabolism, notably during critical windows of development. An abnormal hormonal and inflammatory milieu during development can trigger persistent changes in the function of hypothalamic circuits, le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987771405c43cf7ddbf87b9bcfc5c8f1
https://europepmc.org/articles/PMC9881982/
https://europepmc.org/articles/PMC9881982/
Autor:
Lukas Stilgenbauer, Juliana Bezerra Medeiros de Lima, Lucas Kniess Debarba, Manal Khan, Lisa Koshko, John J. Kopchick, Andrzej Bartke, Augusto Schneider, Marianna Sadagurski
Evidence for hypothalamic regulation of energy homeostasis and thermoregulation in brown adipose tissue (BAT) during aging has been well recognized, yet the central molecular mediators involved in this process are poorly understood. The arcuate hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8af6d9557da3f1911ef2470a9fc27d21
https://doi.org/10.1101/2022.08.31.506031
https://doi.org/10.1101/2022.08.31.506031
Autor:
Lisa Koshko, Sydney Scofield, Lucas Debarba, Lukas Stilgenbauer, Patrick Fakhoury, Hashan Jayarathne, J. Eduardo Perez-Mojica, Ellen Griggs, Adelheid Lempradl, Marianna Sadagurski
Publikováno v:
Chemosphere. 330:138738
Autor:
LUCAS K. DEBARBA, LISA KOSHKO, HASHAN M. JAYARATHNE, ZHENGPING YI, ULRIKE KLUEH, MARIANNA SADAGURSKI
Publikováno v:
Diabetes. 71
There is growing evidence linking exposure to volatile organic compounds (VOC) in ambient air with metabolic disease in humans. Benzene is a prominent VOC present in water, food, detergents, vehicle exhaust, tobacco smoke, and e-cigarettes. However,
Autor:
Kezhong Zhang, Patrick Fakhoury, Juliana Bezerra Medeiros de Lima, Ulrike Klueh, Abear Ali Awada, Lucas Kniess Debarba, Marianna Sadagurski, Adam Mulka, Olesya Didyuk, Lisa Koshko
Publikováno v:
Brain, Behavior, and Immunity. 89:87-99
Benzene is a well-known human carcinogen that is one of the major components of air pollution. Sources of benzene in ambient air include cigarette smoke, e-cigarettes vaping and evaporation of benzene containing petrol processes. While carcinogenic e
Intrinsic Sexual Dimorphism in the Placenta Determines the Differential Response to Benzene Exposure
Autor:
Anthony Maxwell, Nicholas Adzibolosu, Anna Hu, Yuan You, Paul M. Stemmer, Douglas M. Ruden, Michael C. Petriello, Marianna Sadagurski, Lucas K. Debarba, Lisa Koshko, Jayanth Ramadoss, Annie Thy Nguyen, Darby Richards, Aihua Liao, Gil Mor, Jiahui Ding
Publikováno v:
SSRN Electronic Journal.
Autor:
Olesya Didyuk, Lucas Kniess Debarba, Mikaela Sacla, Marianna Sadagurski, Patrick Fakhoury, Juliana Bezerra Medeiros de Lima, Lisa Koshko
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 180(2)
Environmental chemicals play a significant role in the development of metabolic disorders, especially when exposure occurs early in life. We have recently demonstrated that benzene exposure, at concentrations relevant to cigarette smoke, induces a se