Zobrazeno 1 - 10
of 47
pro vyhledávání: '"LIPT1"'
Autor:
Bick, Nolan R. 1, Dreishpoon, Margaret B. 2, Perry, Ava 1, Rogachevskaya, Anna 2, Bottomley, Sylvia S. 3, Fleming, Mark D. 4, Ducamp, Sarah 4, Tsvetkov, Peter 1, 2, ∗
Publikováno v:
In Journal of Biological Chemistry December 2024 300(12)
Autor:
Chunwei Li, Lili Zhu, Qinghua Liu, Mengle Peng, Jinhai Deng, Zhirui Fan, Xiaoran Duan, Ruyue Xue, Zhiping Guo, Xuefeng Lv, Lifeng Li, Jie Zhao
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34011- (2024)
Cancer is widely regarded as a leading cause of death in humans, with colon adenocarcinoma (COAD) ranking among the most prevalent types. Cuproptosis is a novel form of cell death mediated by protein lipoylation. Cuproptosis-related genes (CRGs) part
Externí odkaz:
https://doaj.org/article/857684385b5e4c57b999f9ddec7ae7fe
Autor:
David Gómez-Fernández, Ana Romero-González, Juan M. Suárez-Rivero, Paula Cilleros-Holgado, Mónica Álvarez-Córdoba, Rocío Piñero-Pérez, José Manuel Romero-Domínguez, Diana Reche-López, Alejandra López-Cabrera, Salvador Ibáñez-Mico, Marta Castro de Oliveira, Andrés Rodríguez-Sacristán, Susana González-Granero, José Manuel García-Verdugo, José A. Sánchez-Alcázar
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 1023 (2024)
Mutations in the lipoyltransferase 1 (LIPT1) gene are rare inborn errors of metabolism leading to a fatal condition characterized by lipoylation defects of the 2-ketoacid dehydrogenase complexes causing early-onset seizures, psychomotor retardation,
Externí odkaz:
https://doaj.org/article/3e5f8306564c49ea85740f0320439a87
Publikováno v:
Biomolecules & Biomedicine (2023)
Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related deaths, necessitating a deeper understanding of novel cell death pathways like cuproptosis. This study explored the relevance of cuproptosis-related genes in NSCLC and their pote
Externí odkaz:
https://doaj.org/article/24cbe2f771aa406b98e5f294cefb4616
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Liver hepatocellular carcinoma (LIHC) ranks sixth among the most common types of cancer with a high mortality rate. Cuproptosis is a newly discovered type of cell death in tumor, which is characterized by accumulation of intracell
Externí odkaz:
https://doaj.org/article/66eb35af6a8b48ecb5ac6ea5268f3919
Autor:
Xiaolin Yang, Xiaoqing Zhang, Kaifeng Shen, Zhongke Wang, Guolong Liu, Kaixuan Huang, Zeng He, Yang Li, Zhi Hou, Shengqing Lv, Chunqing Zhang, Hui Yang, Shiyong Liu, Yanyan Ke
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Temporal lobe epilepsy (TLE) is the most common subtype of epilepsy in adults and is characterized by neuronal loss, gliosis, and sprouting mossy fibers in the hippocampus. But the mechanism underlying neuronal loss has not been fully e
Externí odkaz:
https://doaj.org/article/fec8f5fec2734e11af29cdf228b5acbe
Akademický článek
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Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
As a key copper homeostasis-related molecule, lipoyltransferase 1 (LIPT1) is an essential enzyme for the activation of mitochondrial 2-ketoacid dehydrogenase, participating in fatty acylation. However, the biological significances of LIPT1 in the pan
Externí odkaz:
https://doaj.org/article/bbe5bea955d24e38b56d1b44857a6989
Comprehensive Analysis of Cuproptosis-Related Genes in Immune Infiltration and Prognosis in Melanoma
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Skin cutaneous melanoma (SKCM, hereafter referred to as melanoma) is the most lethal skin cancer with increasing incidence. Regulated cell death plays an important role in tumorigenesis and serves as an important target for almost all treatment strat
Externí odkaz:
https://doaj.org/article/f07169da13f645cab274f23d985632d0
Akademický článek
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