Zobrazeno 1 - 10
of 1 110
pro vyhledávání: '"LINKED N-ACETYLGLUCOSAMINE"'
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 12, Pp 1882-1887 (2024)
AIM:To analyze the expression changes of O-linked N-acetylglucosamine(O-GlcNAc)glycoprotein in the lens capsule of age-related cataract and diabetic cataract and investigate the role of O-GlcNAc glycoprotein in diabetic cataract.METHODS: The lens cap
Externí odkaz:
https://doaj.org/article/8682b9e3e70146758861efd1fda11db2
Publikováno v:
In International Immunopharmacology 10 January 2025 144
Autor:
Abigail O. Ayodele, Brenda Udosen, Olugbenga O. Oluwagbemi, Elijah K. Oladipo, Idowu Omotuyi, Itunuoluwa Isewon, Oyekanmi Nash, Opeyemi Soremekun, Segun Fatumo
Publikováno v:
BMC Research Notes, Vol 17, Iss 1, Pp 1-8 (2024)
Abstract O-GlcNAcylation is a nutrient-sensing post-translational modification process. This cycling process involves two primary proteins: the O-linked N-acetylglucosamine transferase (OGT) catalysing the addition, and the glycoside hydrolase OGA (O
Externí odkaz:
https://doaj.org/article/56cb4c8f63d44d858035d2fcf0a42d07
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background The level of linked N-acetylglucosamine (O-GlcNAc) has been proved to be a sensor of cell state, but its relationship with hyperoxia-induced alveolar type 2 epithelial cells injure and bronchopulmonary dysplasia (BPD) has not been
Externí odkaz:
https://doaj.org/article/0d6c8a8be8b2492ca0ba99770ba82908
Akademický článek
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Autor:
Seokwon Jo, Samantha Pritchard, Alicia Wong, Nandini Avula, Ahmad Essawy, John Hanover, Emilyn U. Alejandro
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Protein O-GlcNAcylation is a nutrient and stress-sensitive protein post-translational modification (PTM). The addition of an O-GlcNAc molecule to proteins is catalyzed by O-GlcNAc transferase (OGT), whereas O-GlcNAcase (OGA) enzyme is responsible for
Externí odkaz:
https://doaj.org/article/c526a5a84dea408e9ce3e1b64026f57d
Autor:
Katsutaro Morino, Hiroshi Maegawa
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 2, Pp 130-136 (2021)
Abstract Recent studies using genetically manipulated mouse models have shown the pivotal role of O‐linked N‐acetylglucosamine modification (O‐GlcNAcylation) in the metabolism of multiple organs. The molecular mechanism involves the sensing of
Externí odkaz:
https://doaj.org/article/f1f8d7ae0e344a9b9eda5d944a60c6eb
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
The centrosome apparatus is vital for spindle assembly and chromosome segregation during mitotic divisions. Its replication, disjunction and separation have to be fine-tuned in space and time. A multitude of post-translational modifications (PTMs) ha
Externí odkaz:
https://doaj.org/article/3274d2457a3348c1acb2a490881f37d4
Autor:
Yang Shu, Lingling He, Meixin Gao, Fan Xiao, Junru Yang, Shiwei Wang, Herui Wei, Fuyang Zhang, Hongshan Wei
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
BackgroundA preliminary study by our group revealed that the deficiency of EGF domain-specific O-linked N-acetylglucosamine transferase (EOGT) impaired regulatory T-cell differentiation in autoimmune hepatitis. Nevertheless, the prognostic value of E
Externí odkaz:
https://doaj.org/article/7fd3c8ec805e498aa97c07be7e616ebf
Autor:
Martinović Vesna I., Arambašić-Jovanović Jelena D., Bogojević Desanka B., Ivanović Anđelija S., Otašević Vesna M., Stančić Ana T., Grigorov Ilijana I.
Publikováno v:
Archives of Biological Sciences, Vol 72, Iss 4, Pp 555-565 (2020)
Haptoglobin (Hp) is a hemoglobin-binding protein that prevents free hemoglobin-induced tissue oxidative damage. In streptozotocin-induced diabetic rats, the initial elevation of Hp expression in the serum and liver tends to decrease with diabetes pro
Externí odkaz:
https://doaj.org/article/d5410168f2d94d45b10fdd23a4148865