Zobrazeno 1 - 10
of 7 436
pro vyhledávání: '"LINKED GLYCOSYLATION"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract During tumorigenesis and progression, the immune checkpoint programmed death-1 (PD-1) and its ligand programmed death ligand-1 (PD-L1) play critical roles in suppressing T cell-mediated anticancer immune responses, leading to T-cell exhausti
Externí odkaz:
https://doaj.org/article/a4124b8f64a04271bfd53a346b54dbba
Autor:
Luisa N. Pimentel-Vera, Alexander Rodríguez-López, Angela J. Espejo-Mojica, Aura María Ramírez, Carolina Cardona, Luis H. Reyes, Shunji Tomatsu, Thapakorn Jaroentomeechai, Matthew P. DeLisa, Oscar F. Sánchez, Carlos J. Alméciga-Díaz
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32555- (2024)
Mucopolysaccharidosis IVA (MPS IVA) is a lysosomal storage disease caused by mutations in the gene encoding the lysosomal enzyme N-acetylgalactosamine-6-sulfate sulfatase (GALNS), resulting in the accumulation of keratan sulfate (KS) and chondroitin-
Externí odkaz:
https://doaj.org/article/c416a701f4074f4abb9006fd40dbe25c
Autor:
Amélie Ducloy, Marianne Azzopardi, Caroline Ivsic, Gwendal Cueff, Delphine Sourdeval, Delphine Charif, Jean-Luc Cacas
Publikováno v:
Data in Brief, Vol 53, Iss , Pp 110243- (2024)
The Unfolded Protein Response (UPR) is a retrograde, ER-to-nucleus, signalling pathway which is conserved across kingdoms. In plants, it contributes to development, reproduction, immunity and tolerance to abiotic stress. This RNA sequencing (RNA-seq)
Externí odkaz:
https://doaj.org/article/ad3df57fe627413aad79430be7d69f5b
Publikováno v:
Journal of Hepatocellular Carcinoma, Vol Volume 10, Pp 1749-1765 (2023)
Shusheng Lin,1,2,* Yi Cao,3,* Ke Zhu,1,2,4,* Caini Yang,1,2 Xiangping Zhu,2 Honghua Zhang,1,2 Rui Zhang1,2 1Department of Biliary-Pancreatic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of
Externí odkaz:
https://doaj.org/article/a61e1849a53549ee8df5f4dc2713d004
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PRKCSH, also known as Glucosidase II beta subunit (GluIIβ), is a crucial component of the endoplasmic reticulum (ER) quality control system for N-linked glycosylation, essential for identifying and eliminating misfolded proteins. Glucosidase II cons
Externí odkaz:
https://doaj.org/article/719eb1555e144c7e9cb32393775cc4fc
Autor:
Chutima Talabnin, Thanawat Trasaktaweesakul, Pitchanun Jaturutthaweechot, Pundit Asavaritikrai, Dusit Kongnawakun, Atit Silsirivanit, Norie Araki, Krajang Talabnin
Publikováno v:
PeerJ, Vol 12, p e16785 (2024)
Background Changes in protein glycosylation have been reported in various diseases, including cancer; however, the consequences of altered glycosylation in meningiomas remains undefined. We established two benign meningioma cell lines—SUT-MG12 and
Externí odkaz:
https://doaj.org/article/04c3782afa0e479da4bd90f7264dc89e
Autor:
Yanan Cui, Jun Li, Pengpeng Zhang, Dandan Yin, Ziyu Wang, Jiali Dai, Wei Wang, Erbao Zhang, Renhua Guo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Invasive adenocarcinoma (IAC), which is typically preceded by minimally invasive adenocarcinoma (MIA), is the dominant pathological subtype of early-stage lung adenocarcinoma (LUAD). Identifying the molecular events underlying the
Externí odkaz:
https://doaj.org/article/133c4e9c7813470bb20e45ec9117b7f7
Akademický článek
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Autor:
Jing Huang, Yan Guo, Shujuan Yu, Dongshu Wang, Shulei Li, Jun Wu, Peng Sun, Li Zhu, Hengliang Wang, Chao Pan
Publikováno v:
Virulence, Vol 14, Iss 1 (2023)
ABSTRACTBrucellosis, caused by Brucella, is a severe zoonosis, and the current Brucella live attenuated vaccine cannot be used in humans due to major safety risks. Although polysaccharide antigens can be used to prepare the Brucella vaccine, their lo
Externí odkaz:
https://doaj.org/article/1780f6d87441432dbf35c1153ea122a9
Autor:
Hanqing Chen, Yang Zhang, Yu Shen, Liang Jiang, Guangbo Zhang, Xueguang Zhang, Yang Xu, Fengqing Fu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
B7-H6 is a novel immune checkpoint molecule that triggers NK cell cytotoxicity, but the role of N-glycosylation in B7-H6 is poorly understood. We here identified the existence of N-glycosylation of B7-H6 in different cell lines and exogenous expressi
Externí odkaz:
https://doaj.org/article/4b80a1b428784846b22e679710c7b183