Zobrazeno 1 - 10
of 208
pro vyhledávání: '"LINGYAN SHI"'
Autor:
William D. Leineweber, Maya Z. Rowell, Sural K. Ranamukhaarachchi, Alyssa Walker, Yajuan Li, Jorge Villazon, Aida Mestre-Farrera, Zhimin Hu, Jing Yang, Lingyan Shi, Stephanie I. Fraley
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110661- (2024)
Summary: Contact with dense collagen I (Col1) can induce collective invasion of triple negative breast cancer (TNBC) cells and transcriptional signatures linked to poor patient prognosis. However, this response is heterogeneous and not well understoo
Externí odkaz:
https://doaj.org/article/d6077827910e4b4781e32a41c68ddb5c
Autor:
Wenxu Zhang, Yajuan Li, Anthony A. Fung, Zhi Li, Hongje Jang, Honghao Zha, Xiaoping Chen, Fangyuan Gao, Jane Y. Wu, Huaxin Sheng, Junjie Yao, Dorota Skowronska-Krawczyk, Sanjay Jain, Lingyan Shi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Lipids play crucial roles in many biological processes. Mapping spatial distributions and examining the metabolic dynamics of different lipid subtypes in cells and tissues are critical to better understanding their roles in aging and disease
Externí odkaz:
https://doaj.org/article/e4d19d2cd7ce42d29dc0d13cf5953525
Publikováno v:
Light: Science & Applications, Vol 12, Iss 1, Pp 1-3 (2023)
Abstract A new approach for early detection of multiple cancers is presented by integrating SERS spectroscopy of serum molecular fingerprints and machine learning.
Externí odkaz:
https://doaj.org/article/1e225edb40b54f69971879c88c3526b6
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 16, Iss 05 (2023)
Externí odkaz:
https://doaj.org/article/086eaeb208044dd8a571021123a93998
Publikováno v:
Pathology and Oncology Research, Vol 28 (2022)
Background: Long non-coding RNAs (lncRNAs) play a key regulatory role in tumor metabolism. Although hepatocellular carcinoma (HCC) is a metabolic disease, there have been few systematic reports on the association between lncRNA expression and metabol
Externí odkaz:
https://doaj.org/article/9ccd965a428b4c73a15d56cbf9dd9ea5
Publikováno v:
Advanced Science, Vol 9, Iss 15, Pp n/a-n/a (2022)
Abstract Understanding metabolism is of great significance to decipher various physiological and pathogenic processes. While great progress has been made to profile gene expression, how to capture organ‐, tissue‐, and cell‐type‐specific metab
Externí odkaz:
https://doaj.org/article/b245d80de26649bbb6bf39b5a29bd479
Autor:
Wenxu Zhang, Travis J.A. Craddock, Yajuan Li, Mira Swartzlander, Robert R. Alfano, Lingyan Shi
Publikováno v:
Biophysical Reports, Vol 2, Iss 1, Pp 100043- (2022)
Microtubules are self-assembling biological nanotubes made of the protein tubulin that are essential for cell motility, cell architecture, cell division, and intracellular trafficking. They demonstrate unique mechanical properties of high resilience
Externí odkaz:
https://doaj.org/article/f9a51cd833d04facbc681ec5bab65ea1
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Triple negative breast cancer (TNBC) is a particularly aggressive cancer subtype that is difficult to diagnose due to its discriminating epidemiology and obscure metabolome. For the first time, 3D spatial and chemometric analyses uncover the unique l
Externí odkaz:
https://doaj.org/article/eee496f325c14dfd844eaa0f1f3f92e5
Autor:
Yajuan Li, Pegah Bagheri, Phyllis Chang, Audrey Zeng, Jie Hao, Anthony Fung, Jane Y. Wu, Lingyan Shi
Publikováno v:
Frontiers in Aging, Vol 2 (2022)
Emerging studies have shown that lipids and proteins play versatile roles in various aspects of aging. High-resolution in situ optical imaging provides a powerful approach to study the metabolic dynamics of lipids and proteins during aging. Here, we
Externí odkaz:
https://doaj.org/article/0732eea31be54c3c9196e933f85e7c02
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Oxidative imbalance plays an essential role in the progression of many diseases that include cancer and neurodegenerative diseases. Aromatic amino acids (AAA) such as phenylalanine and tryptophan have the capability of escalating oxidative stress bec
Externí odkaz:
https://doaj.org/article/dd05cf1291064c7e98a03d362886740d