Zobrazeno 1 - 10
of 2 585
pro vyhledávání: '"LIN HOU"'
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Objectives To investigate the potential mechanisms of shikonin in preventing and treating periodontitis using network pharmacology and molecular docking methods. Materials and methods The targets of shikonin were obtained in TCMSP and SEA da
Externí odkaz:
https://doaj.org/article/e72978082c3d475f8ebfd2b27ced5a93
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract TWAS have shown great promise in extending GWAS loci to a functional understanding of disease mechanisms. In an effort to fully unleash the TWAS and GWAS information, we propose MTWAS, a statistical framework that partitions and aggregates c
Externí odkaz:
https://doaj.org/article/7375bb35adf9483684114e62d5660b97
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Repair and reconstruction of the myopectineal orifice area using meshes is the mainstay of surgical treatment of inguinal hernias. However, the limitations of existing meshes are becoming increasingly evident in clinical applications; thus,
Externí odkaz:
https://doaj.org/article/a9ca39c8c9de4c279a79151deed22d85
Autor:
Huijuan Zhang, Xiangyang Xuan, Yaping Wang, Zijun Qi, Kexuan Cao, Yingmei Tian, Chaoqun Wang, Junbiao Chang, Zhenzhong Zhang, Lin Hou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 5, Pp 2317-2332 (2024)
Autophagy is an important factor in reducing the efficacy of tumor phototherapy (including PTT and PDT). Accurate regulation of autophagy in tumor cells is a new strategy to improve the anti-tumor efficiency of PTT/PDT. This project intended to const
Externí odkaz:
https://doaj.org/article/564610d60ffd4f0bae3438c7c6099f37
Autor:
Haoqi Zhang, Yuanke Li, Helong Kang, Jingping Lan, Lin Hou, Zhengbang Chen, Fan Li, Yanqin Liu, Jiliang Zhao, Na Li, Yajuan Wan, Yiping Zhu, Zhen Zhao, Hongkai Zhang, Jie Zhuang, Xinglu Huang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Modulating macrophages presents a promising avenue in tumor immunotherapy. However, tumor cells have evolved mechanisms to evade macrophage activation and phagocytosis. Herein, we introduced a bispecific antibody-based nanoengager to facilit
Externí odkaz:
https://doaj.org/article/7134f59c55224e8dbca874ef84d99cf6
Autor:
Yufei Zhang, Yang Li, Lemuge Qi, Tianyu Hang, Peng Wang, Yarong Wang, Caili Wu, Yongqin Wang, Xufen Wang, Lin Hou, Yaxing Ban, Zhidan Zhang, Weiguang Zhou
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionThe escalating occurrence of infectious disease outbreaks in humans and animals necessitates innovative, effective, and integrated research to better comprehend their transmission and dynamics. Viral infection in livestock has led to prof
Externí odkaz:
https://doaj.org/article/88bb0b58e8d84bec92b35cb165eced22
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract An increasing number of studies have indicated the crucial involvement of long non-coding RNAs (lncRNAs) in the onset and progression of malignancies. However, a complete understanding of the molecular mechanism underlying the effect of abno
Externí odkaz:
https://doaj.org/article/0d04b960e6c14ad693f971db0a57cc31
Autor:
Yan Guo, Pan Xiang, Xiaojiao Sun, Wei Liu, Jiafeng Zhou, Bin Yin, Lin Hou, Boqin Qiang, Huiliang Li, Pengcheng Shu, Xiaozhong Peng
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-18 (2024)
Abstract The appropriate and specific response of nerve cells to various external cues is essential for the establishment and maintenance of neural circuits, and this process requires the proper recruitment of adaptor molecules to selectively activat
Externí odkaz:
https://doaj.org/article/fa5fe9a0d6234403a47d361c6702a55f
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThyroid immune-related adverse events (irAEs) associated with immune checkpoint inhibitor (ICI) treatment appear to correlate with a better prognosis. We aimed to investigate clinical biomarkers associated with thyroid irAEs.MethodsWe retro
Externí odkaz:
https://doaj.org/article/fd95a66a1c3e42d5b5ce60747e8f82aa
Publikováno v:
Applied Sciences, Vol 14, Iss 17, p 7476 (2024)
The service performance of chromium-free zinc–aluminum coatings exhibits characteristics from multiple perspectives. Fully considering the physical properties, corrosion resistance, and economic viability of the coatings, this study incorporates th
Externí odkaz:
https://doaj.org/article/01f21892b06a453fa02a5a684e2f37c7