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Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARγ−/−, PPARδ−/−, PPARγδ−/−, or LXRαβ−/− bone marrow

Autor: Chaitra Marathe, Michelle N. Bradley, Cynthia Hong, Lily Chao, Damien Wilpitz, Jon Salazar, Peter Tontonoz

Publikováno v: Journal of Lipid Research, Vol 50, Iss 2, Pp 214-224 (2009)

Macrophage lipid metabolism and inflammatory responses are both regulated by the nuclear receptors PPAR and LXR. Emerging links between inflammation and metabolic disease progression suggest that PPAR and LXR signaling may alter macrophage function a

Externí odkaz: https://doaj.org/article/ec602b12fd2547218612a0d78e6d9bcb

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Diabetes Distress in Young Adults With Youth-Onset Type 2 Diabetes: TODAY2 Study Results

Autor: Paula M. Trief, Diane Uschner, Melinda Tung, Marsha D. Marcus, Maria Rayas, Sarah MacLeish, Ryan Farrell, Joyce Keady, Lily Chao, Ruth S. Weinstock

Publikováno v: Diabetes Care

OBJECTIVETo assess the prevalence of high diabetes distress and associated factors in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY2) study cohort of young adults with youth-onset type 2 diabetes.RESEARCH DESIGN AND METHOD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f55e8701afaf1f3237a48ed126bdee
https://doi.org/10.2337/dc21-1689

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144-LB: Pediatric Type 2 Diabetes Prevalence from Real-World Data in the United States

Autor: LILY CHAO, ALAINA VIDMAR, JUAN ESPINOZA

Publikováno v: Diabetes. 71

Background: The SEARCH for Diabetes in Youth Study has provided critical insights into the epidemiology of pediatric T2D. The 2021 report estimated an annual percent change (APC) in prevalence of 4.8% between 2009 to 2017. Multi-center longitudinal c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41fb8b37b96e639c8c178f9863140b87
https://doi.org/10.2337/db22-144-lb

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5-LB: Dulaglutide in Youth with Type 2 Diabetes (T2D) —Results of the AWARD-PEDS Randomized, Placebo-Controlled Trial

Autor: SILVA A. ARSLANIAN, JANG IK CHO, TAMARA S. HANNON, PHILIP ZEITLER, LILY CHAO, MARGARITA BARRIENTOS, CLAUDIA C. BOUCHER-BERRY, ELISE BISMUTH, SERGIO A. DIB, DAVID COX

Publikováno v: Diabetes. 71

AWARD-PEDS was a Phase 3 trial to assess the efficacy and safety of dulaglutide (DU) , a once-weekly GLP-1 receptor agonist, in youth (10 to In conclusion, in youth with inadequately controlled T2D treated with or without metformin and/or basal insul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a94ad1624552c27b63c2e0263683e66a
https://doi.org/10.2337/db22-5-lb

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980-P: Continuous Glucose Monitor Improves Glycemic Control in Youth-Onset Type 2 Diabetes

Autor: NANCY T. CHANG, JOSEPHINE ANDREA SMITH, LILY CHAO

Publikováno v: Diabetes. 71

Background: Youth with type 2 diabetes (T2D) develop early treatment failure. Most patients do not self-monitor blood glucose (SMBG) levels at recommended frequency. Continuous glucose monitor (CGM) has been shown to improve glycemic control in pedia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a937c02cbc7b983aa981b827158e9956
https://doi.org/10.2337/db22-980-p

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979-P: Risk Factors for Hyperosmolar Hyperglycemic State in Youth-Onset Type 2 Diabetes

Autor: ESTELLE M. EVERETT, LAUREN E. WISK, LILY CHAO

Publikováno v: Diabetes. 71

Background: The prevalence of youth-onset type 2 diabetes (T2D) has been rising. There is a paucity of data on the risk factors for hyperosmolar hyperglycemic state (HHS) compared to diabetic ketoacidosis (DKA) in this population. Methods: We used th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e72129c2f24204587974f7ce30c32aa6
https://doi.org/10.2337/db22-979-p

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Diabetes Distress in Young Adults with Youth-onset Type 2 Diabetes: TODAY2 Study Results

Autor: the TODAY Study Group, Ruth S. Weinstock, Lily Chao, Joyce Keady, Ryan Farrell, Sarah MacLeish, Maria Rayas, Marsha D. Marcus, Melinda Tung, Diane Uschner, Paula M. Trief

Objectives: To assess prevalence of high diabetes distress and associated factors in the Treatment Options for type 2 Diabetes in Adolescents and Youth (TODAY2) cohort of young adults with youth-onset type 2 diabetes. Methods: Participants completed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a7e0a089caadf1dc1f7eef6be27fef
https://doi.org/10.2337/figshare.17136365

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554-P: Diabetes Distress in Young Adults with Youth-Onset Type 2 Diabetes: TODAY Study Results

Autor: Joyce Keady, Marsha D. Marcus, Melinda Tung, Paula M. Trief, Ryan M. Farrell, Ruth S. Weinstock, Maria S. Rayas, Diane Uschner, Sarah A. Macleish, Lily Chao

Publikováno v: Diabetes. 70

Aims: Diabetes distress (DD) is associated with poor health outcomes. Little is known about level of DD in young adults (YAs) with youth-onset type 2 diabetes (T2D) or individual factors associated with DD. Aims were to assess level of DD, and factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02849dc3db951ac4dc551d99108ad4bf
https://doi.org/10.2337/db21-554-p

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