Výsledky vyhledávání - "LILIAN MABUNDO"

Akademický článek

The effects of prebiotics on gastrointestinal side effects of metformin in youth: A pilot randomized control trial in youth-onset type 2 diabetes

Autor: Sydney A. Dixon, Sidharth Mishra, Katrina B. Dietsche, Shalini Jain, Lilian Mabundo, Michael Stagliano, Andrea Krenek, Amber Courville, Shanna Yang, Sara A. Turner, Abby G. Meyers, Doris E. Estrada, Hariom Yadav, Stephanie T. Chung

Publikováno v: Frontiers in Endocrinology, Vol 14 (2023)

Disclosure summaryDr. Yadav is Chief Scientific Officer and Co-Founder of Postbiotics Inc and has no conflict of interest with this work. All other authors have no conflicts of interest to disclose.BackgroundMetformin is the only approved first-line

Externí odkaz: https://doaj.org/article/4fc9277ae95241e49eb69f63c95e1038

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Abstract P560: Pilot Study Reveals Excellent Agreement in the Diagnosis of Diabetes Between the Newly Developed Pastry Sugar Tolerance Test and the OGTT: Africans in America Study

Autor: Blayne R Schenk, Jamaiica Hurston, Jean de Dieu Gatete, Christopher W DuBose, Lilian Mabundo, Shanna Yang, Charlita Worthy, Ram Jagannathan, Amber B Courville, Anne E Sumner

Publikováno v: Circulation. 147

Introduction: Sub-Saharan Africa has the highest percentage of people in the world living with diabetes who are undiagnosed. To avoid end-organ damage, identification of undiagnosed diabetes needs prioritization. Glucola (75g glucose) used for the or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54ef405521a6e3cf8c01c7a4e10a5d17
https://doi.org/10.1161/circ.147.suppl_1.p560

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989-P: Impaired Coronary Arterial Dilation in Youth-Onset Type 2 Diabetes

Autor: ALFREDO VILLALOBOS-PEREZ, JENNA FEELEY, KHALED Z. ABD-ELMONIEM, KATRINA B. DIETSCHE, SYDNEY A. DIXON, JATIN R. MATTA, MICHAEL S. STAGLIANO, LILIAN MABUNDO, EILEEN L. SHOUPPE, AHMED M. GHARIB, MARY WALTER, STEPHANIE T. CHUNG

Publikováno v: Diabetes. 71

Young adults with type 2 diabetes (T2D-Y) have increased risk of subclinical atherosclerotic cardiovascular disease (ASCVD) . Cardiac magnetic resonance imaging (MRI) may guide risk stratification by noninvasively quantifying coronary wall thickness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fd02729ed0a9248811d568de0433871
https://doi.org/10.2337/db22-989-p

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1232-P: Beta-Cell Function and Type 2 Diabetes in Africans and Asian Indians

Autor: LISA R. STAIMEZ, ROHAN SHAH, MOHAN DEEPA, TANDI E. MATSHA, RANJIT MOHAN ANJANA, RAJIV T. ERASMUS, VISWANATHAN MOHAN, LILIAN MABUNDO, CHRISTOPHER DUBOSE, K.M. VENKAT NARAYAN, SAMUEL DAGOGO-JACK, ANDRE PASCAL KENGNE, ANNE E. SUMNER

Publikováno v: Diabetes. 71

The role of β cell dysfunction in the development of type 2 diabetes (DM) is not understood across populations with different levels of insulin resistance. We examined β-cell function in two cohorts of Africans and compared them to Asian Indians. A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb7577f3b4626a2ccdd98738ddec7597
https://doi.org/10.2337/db22-1232-p

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1120-P: Pilot Study Comparison of Newly Developed Pastry Sugar Tolerance Test with the OGTT: Africans in America Study

Autor: M GRACE DUHUZE-KARERA, SHANNA YANG, BLAYNE R. SCHENK, ANNEMARIE WENTZEL, ARIELLE PATTERSON, ZOE C. WALDMAN, CHRISTOPHER DUBOSE, LILIAN MABUNDO, RAM JAGANNATHAN, AMBER B. COURVILLE, ANNE E. SUMNER

Publikováno v: Diabetes. 71

As undiagnosed diabetes (DM) rises in Africa and A1C performs suboptimally, attention turns to the OGTT. Obtaining Glucola (75g glucose) for the OGTT is difficult. Analyzing Africans in America data, we previously found that duplicate OGTT were highl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17e765b944551d4bf489161752dccbc6
https://doi.org/10.2337/db22-1120-p

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991-P: Metformin Plasma Concentration as a Biomarker of Treatment Responsiveness in Youth-Onset Type 2 Diabetes

Autor: KATRINA B. DIETSCHE, ANNA ZENNO, ALFREDO VILLALOBOS-PEREZ, SYDNEY A. DIXON, MICHAEL S. STAGLIANO, LILIAN MABUNDO, EILEEN L. SHOUPPE, DORIS E. ESTRADA, ABBY MEYERS, FRAN R. COGEN, MARY WALTER, PETER WALTER, STEPHANIE T. CHUNG

Publikováno v: Diabetes. 71

Metformin is the first-line therapy for youth-onset type 2 diabetes mellitus (Y-T2D) but is suboptimal in up to 50% of youth. The reasons for increased failure rates are unknown. Metformin plasma concentration reflects total body distribution and kin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79b9398a20b3bd3b8bb3ec423dbde8f2
https://doi.org/10.2337/db22-991-p

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1108-P: Noninvasive Diabetes Risk Scores Identify Diabetes due to Insulin Resistance but Not ß-Cell Failure: The Africans in America Study

Autor: ANNEMARIE WENTZEL, ARIELLE PATTERSON, M GRACE DUHUZE-KARERA, ZOE C. WALDMAN, BLAYNE R. SCHENK, LILIAN MABUNDO, CHRISTOPHER DUBOSE, ANNE E. SUMNER, MARGRETHE F. HORLYCK-ROMANOVSKY

Publikováno v: Diabetes. 71

In low and middle-income countries in Africa, β-cell-failure in the absence of obesity is increasingly recognized as a frequent cause of type 2 diabetes (DM) . DM risk scores assume that insulin resistance (IR) is the primary cause of DM. Therefore,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1db00291d6cd7dfa1f0524c0e828535b
https://doi.org/10.2337/db22-1108-p

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990-P: Prebiotics and Metformin: A Pilot Randomized Controlled Trial in Youth-Onset Type 2 Diabetes

Autor: SYDNEY A. DIXON, ABBY MEYERS, KUNANI TUTTLE, LILIAN MABUNDO, MICHAEL S. STAGLIANO, ALFREDO VILLALOBOS-PEREZ, KATRINA B. DIETSCHE, AMBER B. COURVILLE, DORIS E. ESTRADA, STEPHANIE T. CHUNG

Publikováno v: Diabetes. 71

Metformin is the only first-line oral agent for youth with type 2 diabetes mellitus (Y-T2D) , but efficacy and adherence is complicated by gastrointestinal (GI) side effects. Prebiotic microbiome modulators (MM) may reduce side effects by shifting th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80ec31369c5a1c2f312b8a2992c75e68
https://doi.org/10.2337/db22-990-p

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Improved Detection of Abnormal Glucose Tolerance in Africans: The Value of Combining Hemoglobin A1c With Glycated Albumin

Autor: Stephanie T. Chung, Thomas Hormenu, Elyssa M. Shoup, Joon Ha, David B. Sacks, Anne E. Sumner, Nana H. Osei-Tutu, Arsene F. Hobabagabo, Christopher Dubose, Arthur Sherman, Lilian Mabundo

Publikováno v: Diabetes Care. 43:2607-2613

OBJECTIVE In African-born Blacks living in America, we determined by BMI category 1) prevalence of abnormal glucose tolerance (Abnl-GT) and 2) diagnostic value and reproducibility of hemoglobin A1c (HbA1c), fructosamine, and glycated albumin (GA). RE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cadd02facbcd3d9e95dc420711e2f7
https://doi.org/10.2337/dc20-1119

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Beta-cell failure rather than insulin resistance is the major cause of abnormal glucose tolerance in Africans: insight from the Africans in America study

Autor: Elyssa M. Shoup, M. C. Sage Ishimwe, Joon Ha, Lilian Mabundo, Arielle C Patterson, Annemarie Wentzel, Hadi Bagheri, Thomas Hormenu, Arthur Sherman, Anne E. Sumner, Christopher Dubose, Nana H. Osei-Tutu

Publikováno v: BMJ Open Diabetes Research & Care
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)

IntroductionUncertainties exist on whether the main determinant of abnormal glucose tolerance (Abnl-GT) in Africans is β-cell failure or insulin resistance (IR). Therefore, we determined the prevalence, phenotype and characteristics of Abnl-GT due t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a65254465b247ac8d6e704c8a3724f
https://pubmed.ncbi.nlm.nih.gov/34531244

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