Zobrazeno 1 - 10
of 50
pro vyhledávání: '"LILA M. OYAMA"'
Autor:
Ionel Sandovici, Denise S. Fernandez-Twinn, Niamh Campbell, Wendy N. Cooper, Yoichi Sekita, Ilona Zvetkova, David Ferland-McCollough, Haydn M. Prosser, Lila M. Oyama, Lucas C. Pantaleão, Danilo Cimadomo, Karina Barbosa de Queiroz, Cecilia S.K. Cheuk, Nicola M. Smith, Richard G. Kay, Robin Antrobus, Katharina Hoelle, Marcella K.L. Ma, Noel H. Smith, Stefan H. Geyer, Lukas F. Reissig, Wolfgang J. Weninger, Kenneth Siddle, Anne E. Willis, Brian Y.H. Lam, Martin Bushell, Susan E. Ozanne, Miguel Constância
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114750- (2024)
Summary: Mir483 is a conserved and highly expressed microRNA in placental mammals, embedded within the Igf2 gene. Its expression is dysregulated in a number of human diseases, including metabolic disorders and certain cancers. Here, we investigate th
Externí odkaz:
https://doaj.org/article/abbc32c9c19d41bf953422abe96dc435
Autor:
Gislene B. Lima, Nayra Figueiredo, Fabiana M. Kattah, Emilly S. Oliveira, Maria A. Horst, Ana R. Dâmaso, Lila M. Oyama, Renata G. M. Whitton, Gabriel I. M. H. de Souza, Glaucia C. Lima, João F. Mota, Raquel M. S. Campos, Flávia C. Corgosinho
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2248 (2024)
Background: Inflammation plays a central role in many chronic diseases that characterize modern society. Leptin/adiponectin and adiponectin/leptin ratios have been recognized as notable markers of dysfunctional adipose tissue and, consequently, an in
Externí odkaz:
https://doaj.org/article/9512ec62120d4a8fb94cc8cc8e9d4abe
Autor:
Thaís Alves-Silva, Talita G.R. Húngaro, Leandro C. Freitas-Lima, Gabriel de Melo Arthur, Adriano C. Arruda, Raisa B. Santos, Lila M. Oyama, Marcelo A.S. Mori, Michael Bader, Ronaldo C. Araujo
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108409- (2023)
Summary: Given the importance of the kinin B1 receptor in insulin and leptin hormonal regulation, which in turn is crucial in maternal adaptations to ensure nutrient supply to the fetus, we investigated the role of this receptor in maternal metabolis
Externí odkaz:
https://doaj.org/article/b0fd0e8a5a0047ef83ca5610a3479922
Autor:
ADRIANA P. DE SOUZA, LORENZA OLIVEIRA T. CARVALHO, AMANDA PAULA PEDROSO, AMANDA DE SANTOS MORAES, MARCOS ALBERTO TADDEO CIPULLO, ANA RAIMUNDA DÂMASO, MÔNICA M. TELLES, LILA M. OYAMA, ALEXANDRE K. TASHIMA, DANIELLE A. CARANTI, ELIANE B. RIBEIRO
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 95, Iss suppl 2 (2023)
Abstract Obesity and depression, disorders associated with inflammation, have high incidences in women. Understanding the derangements present in the initial phase of obesity may point to factors that could help avoiding disease aggravation. The pres
Externí odkaz:
https://doaj.org/article/ebc295c58dd543508c2eeacdf9df719e
Autor:
Bruna K.S. Hirata, Alexandre H. Aono, Meira M.F. Machado, Ellen C. Joyce, Allain A. Bueno, Reginaldo M. Kuroshu, Lila M. Oyama, Eliane B. Ribeiro, Cristina V. Niero, Monica M. Telles
Publikováno v:
Phytomedicine Plus, Vol 3, Iss 3, Pp 100467- (2023)
Background: Gut microbiota (GM) modulation has been considered a nutritional approach to manage obesity. Reduced Firmicutes/Bacteroidetes ratio (F/B) is associated with reduced energy harvesting capacity from the diet, ameliorates endotoxemia and inf
Externí odkaz:
https://doaj.org/article/3f815c338ec94392bfaf233a14cddc3e
Autor:
Jessica M. V. Pino, Vitória F. Silva, Marcos Mônico-Neto, Danielle C. Seva, Melissa Y. Kato, July N. Alves, Gabriela C. Pereira, Hanna Karen M. Antunes, Thales D. Galvao, Lia R. A. Bitterncourt, Sergio Tufik, Lysien I. Zambrano, Ana R. Dâmaso, Lila M. Oyama, David Thivel, Raquel M. S. Campos, Kil S. Lee
Publikováno v:
International Journal of Endocrinology, Vol 2023 (2023)
Objective. Obesity is one of the modifiable risk factors for dementia. Insulin resistance, the abundance of advanced glycated end-products, and inflammation are some of the mechanisms associated with the lower cognitive performance observed in obesit
Externí odkaz:
https://doaj.org/article/8ea9601f33c84fb9b31a38ae3ef5b1c3
Autor:
Gustavo B. Lamy, Eduardo M. Cafarchio, Bárbara do Vale, Bruno B. Antonio, Daniel P. Venancio, Janaina S. de Souza, Rui M. Maciel, Gisele Giannocco, Artur F. Silva Neto, Lila M. Oyama, Patrik Aronsson, Monica A. Sato
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Angiotensin-(1–7) is a peptide produced by different pathways, and regardless of the route, the angiotensin-converting enzyme 2 (ACE-2) is involved in one of the steps of its synthesis. Angiotensin-(1–7) binds to Mas receptors localized in differ
Externí odkaz:
https://doaj.org/article/d8d901adb3aa481bb61e0857bdf17598
Autor:
Bruna K.S. Hirata, Amanda P. Pedroso, Meira M.F. Machado, Nelson I.P. Neto, Bruna O. Perestrelo, Roberta D.C.C. de Sá, Maria Isabel C. Alonso-Vale, Fernando N. Nogueira, Lila M. Oyama, Eliane B. Ribeiro, Alexandre K. Tashima, Monica M. Telles
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The rapid increase in the number of individuals with obesity, over the past four decades, is triggered by a number of complex interactions among factors. Despite the plethora of treatments available, side effects are commonly observed and, in this co
Externí odkaz:
https://doaj.org/article/61b7884d2361434794b018ba1f267b15
Autor:
Ana P. S. Dornellas, Valter T. Boldarine, Amanda P. Pedroso, Lorenza O. T. Carvalho, Iracema S. de Andrade, Tânia M. Vulcani-Freitas, Carla C. C. dos Santos, Cláudia M. da Penha Oller do Nascimento, Lila M. Oyama, Eliane B. Ribeiro
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Externí odkaz:
https://doaj.org/article/0c05fe336a7c4b74aa13ecb1608fba1b
Autor:
Ana P. S. Dornellas, Valter T. Boldarine, Amanda P. Pedroso, Lorenza O. T. Carvalho, Iracema S. de Andrade, Tânia M. Vulcani-Freitas, Carla C. C. dos Santos, Cláudia M. da Penha Oller do Nascimento, Lila M. Oyama, Eliane B. Ribeiro
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Menopause-induced changes may include increased incidence of both depression/anxiety and obesity. We hypothesized that behavioral changes that may develop after ovarian failure could be related to neurochemical and metabolic aspects affected by this
Externí odkaz:
https://doaj.org/article/efc67fad7c2042d29107018903cb9009