Zobrazeno 1 - 10
of 29 848
pro vyhledávání: '"LI LIANG"'
Autor:
Sisi Zeng, Huiling Hu, Zhiyang Li, Qi Hu, Rong Shen, Mingzhou Li, Yunshi Liang, Zuokang Mao, Yandong Zhang, Wanqi Zhan, Qin Zhu, Feifei Wang, Jianbiao Xiao, Bohan Xu, Guanglong Liu, Yanan Wang, Bingsong Li, Shaowan Xu, Zhaowen Zhang, Ceng Zhang, Zhizhang Wang, Li Liang
Publikováno v:
Cancer Communications, Vol 44, Iss 11, Pp 1287-1310 (2024)
Abstract Background Dysfunction of CD8+ T cells in the tumor microenvironment (TME) contributes to tumor immune escape and immunotherapy tolerance. The effects of hormones such as leptin, steroid hormones, and glucocorticoids on T cell function have
Externí odkaz:
https://doaj.org/article/8f4ff07dafaf46e7bf37b3eed83a199c
Autor:
Jin Wang, Lijun Huang, Juan Li, Rui Xu, Tao Guo, Tong Huang, Yanping Wu, Yang Yang, Jiale Zhang, Feng Jiang, Huan Liu, Li Liang, Lei Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Hypertrophic scars arise from aberrant wound healing and can lead to functional and aesthetic impairments. One of the common interventions for treating hypertrophic scars is fractional carbon dioxide (CO2) laser, which employs narrow laser b
Externí odkaz:
https://doaj.org/article/e48844769ba84506b48d3091e07ecb60
Autor:
Hairong Xu, Yong Zhou, Li Liang, Jingnan Shen, Wangjun Yan, Jin Wang, Jianmin Li, Xiaojing Zhang, Gang Huang, Wenzhi Bi, Zheng Guo, Yanbin Xiao, Jianhua Lin, Weitao Yao, Zhichao Tong, Wenxian Zhou, Guochuan Zhang, Zhaoming Ye, Dong Wang, Jilong Yang, Zhengfu Fan, Caigang Liu, Guofan Qu, Qing Zhang, Feng Wei, Weifeng Liu, Chongqi Tu, Hong Li, Jing Yuan, Xiaohui Niu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract This was a multicenter, single-arm, open-label, phase Ib/II study (NCT04255576), aimed to evaluate the efficacy and safety of JMT103 in patients with unresectable or surgically-challenging giant cell tumor of bone (GCTB). JMT103 (2 mg/kg) wa
Externí odkaz:
https://doaj.org/article/55d90559901a45d7b87e4d04f7225e5a
Autor:
Jing Wu, Shilong Zhang, Shan Yu, Guo An, Yi Wang, Yiyi Yu, Li Liang, Yan Wang, Xiaojing Xu, YanShi Xiong, Di Shao, Zhun Shi, Nannan Li, Jingyuan Wang, Dawei Jin, Tianshu Liu, Yuehong Cui
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Vascular endothelial growth factor inhibitors, including tyrosine kinase inhibitors (TKIs), possess immunomodulatory properties and have shown promising outcomes when combined with anti-PD-1 antibodies. The OASIS phase II trial (NCT04503967)
Externí odkaz:
https://doaj.org/article/02bedb12c5e649a694ae55e114afd924
Publikováno v:
BMC Medical Imaging, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Objective To evaluate value of Nomogram prediction model based on CTA imaging features for selecting treatment methods for isolated superior mesenteric artery dissection (ISMAD). Methods Symptomatic ISMAD patients were randomly divided into
Externí odkaz:
https://doaj.org/article/bc4ea1101dcb4d01809d654abdb7a231
Publikováno v:
Liang you shipin ke-ji, Vol 32, Iss 5, Pp 26-34 (2024)
The use of weak passwords is a significant vulnerability in computer information system security, and this issue is also present in the digital applications of grain storage information systems. Simple hashing algorithms have obvious limitations when
Externí odkaz:
https://doaj.org/article/647128a05bac48f0a83808de1c42de8d
Autor:
Nana Geng, Mengtian Fan, Biao Kuang, Fengmei Zhang, Menglin Xian, Lin Deng, Cheng Chen, Yiming Pan, Jianqiang Chen, Naibo Feng, Li Liang, Yuanlan Ye, Kaiwen Liu, Xiaoli Li, Yu Du, Fengjin Guo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Osteoarthritis is a degenerative joint disease with joint pain as the main symptom, caused by fibrosis and loss of articular cartilage. Due to the complexity and heterogeneity of osteoarthritis, there is a lack of effective individualized di
Externí odkaz:
https://doaj.org/article/bba95520904141e3b43de147af0e85d8
Autor:
Xiaojing Xu, Luoyan Ai, Keshu Hu, Li Liang, Minzhi Lv, Yan Wang, Yuehong Cui, Wei Li, Qian Li, Shan Yu, Yi Feng, Qing Liu, Ying Yang, Jiao Zhang, Fei Xu, Yiyi Yu, Tianshu Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Immunotherapy confers little to no benefit in the treatment of microsatellite stable (MSS) metastatic colorectal cancer (mCRC). Mechanistic insights suggested that epidermal growth factor receptor (EGFR) antibody plus irinotecan might augmen
Externí odkaz:
https://doaj.org/article/c52ef4cf4de347268916103efecfb9a4
Autor:
Jie Wang, Zilong Zhang, Yan Zhuo, Zhuan Zhang, Rongrong Chen, Li Liang, Xiaohe Jiang, Di Nie, Chang Liu, Zhiwen Zou, Xiang Li, Jiaxin Li, Bingqi Wang, Rui Wang, Yong Gan, Miaorong Yu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3643-3660 (2024)
The prospect of employing chemoimmunotherapy targeted towards the endoplasmic reticulum (ER) presents an opportunity to amplify the synergistic effects of chemotherapy and immunotherapy. In this study, we initially validated celastrol (CEL) as an ind
Externí odkaz:
https://doaj.org/article/8cd666c37ea84775a898da7c02d10cf7
Autor:
Qing Chen, Tao Huang, Liping Zou, Xianzhen Tang, Zhengyu Shi, Xinwei Wang, Huaige Wu, Jiying Sun, Xiaoli Lu, Li Liang, Liangshuang Jiang, Dafeng Liu, Shenjie Tang, Guihui Wu, Wei He
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The treatment of multidrug-resistant tracheobronchial tuberculosis poses challenges, and research investigating the efficacy of bedaquiline or delamanid as treatment for this condition is limited. This retrospective cohort study was conducte
Externí odkaz:
https://doaj.org/article/f7a75edc530442f6ac18415b847fa6f1