High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model

Autor: Francesca Fumagalli, Giuseppe Ristagno, Luca Ronda, Esra'a Alomari, Davide Olivari, Gianluca Paredi, Roberto Latini, Chris E. Cooper, Stefano Bettati, Marialaura Marchetti, Deborah Novelli, Andrea Mozzarelli, Brandon J. Reeder, Stefano Bruno

Publikováno v: Free Radical Biology & Medicine
Free radical biology & medicine 124 (2018): 299–310. doi:10.1016/j.freeradbiomed.2018.06.018
info:cnr-pdr/source/autori:Alomari E, Ronda L, Bruno S, Paredi G, Marchetti ML, Bettati S, Olivari D, Fumagalli F, Novelli D, Ristagno G, Latini R, Cooper CE, Reeder BJ, Mozzarelli A/titolo:High-and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model/doi:10.1016%2Fj.freeradbiomed.2018.06.018/rivista:Free radical biology & medicine/anno:2018/pagina_da:299/pagina_a:310/intervallo_pagine:299–310/volume:124

Hemoglobin-based oxygen carriers (HBOCs) are an investigational replacement for blood transfusions and are known to cause oxidative damage to tissues. To investigate the correlation between their oxygen binding properties and these detrimental effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9239f8501b395e8185e06c719d030dd9
http://europepmc.org/articles/PMC6191936