Zobrazeno 1 - 10
of 323
pro vyhledávání: '"LGR4"'
Autor:
Jie Zhang, Jinhai Jiang, Hang Liu, Shiyu Wang, Kaixin Ke, Siyuan Liu, Yue Jiang, Lu Liu, Xiang Gao, Baicheng He, Yuxi Su
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 101075- (2024)
Bone defects and non-union are prevalent in clinical orthopedy, and the outcomes of current treatments are often suboptimal. Bone tissue engineering offers a promising approach to treating these conditions effectively. Bone morphogenetic protein 9 (B
Externí odkaz:
https://doaj.org/article/3b60a618d69b4890ad11935b3c1feda7
Autor:
Sara Fernández-Villabrille, Julia Martín-Vírgala, Beatriz Martín-Carro, Francisco Baena-Huerta, Nerea González-García, Helena Gil-Peña, Minerva Rodríguez-García, Jesús María Fernández-Gómez, José Luis Fernández-Martín, Cristina Alonso-Montes, Manuel Naves-Díaz, Natalia Carrillo-López, Sara Panizo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5735 (2024)
Vascular calcification has a global health impact that is closely linked to bone loss. The Receptor Activator of Nuclear Factor Kappa B (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) system, fundamental for bone metabolism, also plays an important
Externí odkaz:
https://doaj.org/article/4ba47218492a441ba9365471d5999937
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol Volume 16, Pp 619-628 (2023)
Yujing He,1 Na Wu1,2 1Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of China; 2Department of Medical Service Quality, Shengjing Hospital of China Medical University, Shenyang, People’s Re
Externí odkaz:
https://doaj.org/article/59bdc3c4649e46f8b59123526e65a5ba
Autor:
Dike Qiu, Ke Xu, Namjin Chung, Jennifer Robbins, Robert Luo, Michael Lawrence, Aiqing He, Fei Yu, Andrew Alt, Michael M. Miller, Jon Hangeland, John N. Feder, Dietmar Seiffert, Brian J. Arey
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Vascular endothelial cells are exposed to mechanical forces due to their presence at the interface between the vessel wall and flowing blood. The patterns of these mechanical forces (laminar vs. turbulent) regulate endothelial cell function and play
Externí odkaz:
https://doaj.org/article/f3f3dd00eded4a689dfaf7ecdb19176f
Publikováno v:
Genetics and Molecular Biology, Vol 45, Iss 3 (2022)
ABSTRACT MicroRNA-137 (miR-137) has recently emerged as an osteogenic regulator in several cell lines. This study aimed to identify the function of miR-137 on the crosstalk between leucine rich repeat containing G protein-coupled receptor 4 (LGR4) an
Externí odkaz:
https://doaj.org/article/18ba84983eaa4518a6829e5c73def456
Akademický článek
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Akademický článek
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Autor:
Joanna Filipowska, Nagesha G. Kondegowda, Nancy Leon-Rivera, Sangeeta Dhawan, Rupangi C. Vasavada
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4/GPR48), a member of the GPCR (G protein-coupled receptors) superfamily, subfamily B, is a common intestinal crypt stem cell marker. It binds R-spondins/Norrin as classical ligands and
Externí odkaz:
https://doaj.org/article/be94f9f3296b45a694f8968b47c9bfc6
Autor:
Linlin Yang, Jing Wang, Xiaodi Gong, Qiong Fan, Xiaoming Yang, Yunxia Cui, Xiaoyan Gao, Lijuan Li, Xiao Sun, Yuhong Li, Yudong Wang
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
The leucine-rich repeats containing G protein-coupled receptor 4 (LGR4) belonging to G protein-coupled receptors (GPCRs) family, had various regulatory roles at multiple cellular types and numerous targeting sites, and aberrant LGR4 signaling played
Externí odkaz:
https://doaj.org/article/2467ed2472984f5fa62d8e5904edd46c
Autor:
Su-qin Shi, Shan-shan Li, Xiao-ya Zhang, Zhe Wei, Wen-zhen Fu, Jin-wei He, Yun-qiu Hu, Miao Li, Li-li Zheng, Zhen-lin Zhang
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
ObjectiveThe current study was conducted to determine whether peak bone mineral density (BMD) and obesity phenotypes are associated with certain LGR4 gene polymorphisms found in Chinese nuclear families with female children.MethodsA total of 22 singl
Externí odkaz:
https://doaj.org/article/a75257226dfe4004bd70a18eb2828f98