Zobrazeno 1 - 10
of 57
pro vyhledávání: '"LGIC"'
Autor:
Stevens, Alexander
Structural biology has become an important part of researching various diseases and drug development. In this thesis, I provide details on how I worked with approaches to structural characterization of a heteromeric GABA(A)R. These pentameric ligand
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-323235
Akademický článek
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Akademický článek
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Publikováno v:
Channels
β-Phenylethylamine (βPEA) is a trace amine present in the CNS of all animals tested to date. However, its function is still not fully understood. βPEA has been suggested to function as a neurotransmitter and/or to mimic the effect of amphetamine (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6559c0928ebd4fcd95193f24a9d94634
https://doi.org/10.1523/jneurosci.3100-13.2014
https://doi.org/10.1523/jneurosci.3100-13.2014
Autor:
Linda Silvestri, Rogier A. Smits, Sarah C. R. Lummis, Andrew J. Thompson, Rob Leurs, Jacqueline E. van Muijlwijk-Koezen, Saskia Hulscher, Chris de Graaf, Obbe P. Zuiderveld, Gerdien E. de Kloe, Henry F. Vischer, Mark H.P. Verheij, Saskia Nijmeijer, Iwan J. P. de Esch
Publikováno v:
Bioorganic & Medicinal Chemistry Letters
Graphical abstract
A fragment library was screened against the G protein-coupled histamine H4 receptor (H4R) and the ligand-gated ion channel serotonin 5-HT3A (5-HT3AR). Interestingly, significant overlap was found between H4R and 5-HT3AR hit se
A fragment library was screened against the G protein-coupled histamine H4 receptor (H4R) and the ligand-gated ion channel serotonin 5-HT3A (5-HT3AR). Interestingly, significant overlap was found between H4R and 5-HT3AR hit se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52e42d222c6c62125893e7bac70bb4a
https://doi.org/10.1016/j.bmcl.2011.06.123
https://doi.org/10.1016/j.bmcl.2011.06.123
Akademický článek
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Autor:
Todorovic, Jelena, 1981
Glycine receptors (GlyRs) are ligand-gated ion channels (LGICs) that, along with other members of the cys-loop superfamily of receptors, mediate a considerable portion of fast neurotransmission in the central nervous system (CNS). GlyRs are pentameri
Externí odkaz:
http://hdl.handle.net/2152/ETD-UT-2010-12-2140
Publikováno v:
Neuroscience 2008, Washington D.C., 2008
info:cnr-pdr/source/autori:M. P. MASCIA, D. FABBRI, M. DETTORI, C. COSSU, M. SERRA, S. CARTA, G. DELOGU, G. BIGGIO/congresso_nome:Neuroscience 2008/congresso_luogo:Washington D.C./congresso_data:2008/anno:2008/pagina_da:/pagina_a:/intervallo_pagine
info:cnr-pdr/source/autori:M. P. MASCIA, D. FABBRI, M. DETTORI, C. COSSU, M. SERRA, S. CARTA, G. DELOGU, G. BIGGIO/congresso_nome:Neuroscience 2008/congresso_luogo:Washington D.C./congresso_data:2008/anno:2008/pagina_da:/pagina_a:/intervallo_pagine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=cnr_________::bbcee85106e3355ac284fc1517710e6e
http://www.cnr.it/prodotto/i/104543
http://www.cnr.it/prodotto/i/104543
Autor:
Xiu, Xinan Joanne
Nicotinic acetylcholine receptors (nAChR) are an important family of ligand gated ion channels found throughout the CNS and the PNS. They have been indicated in a series of physiological functions and pathological states. nAChRs have received extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75fac3a4d8b1434eda2ff64781c6ca24
Publikováno v:
136 (2003): 329–342.
info:cnr-pdr/source/autori:Kass-Simon G.1, Pannaccione A.2, Pierobon P.3/titolo:GABA and glutamate receptors are involved in modulating pacemaker activity in hydra/doi:/rivista:/anno:2003/pagina_da:329/pagina_a:342/intervallo_pagine:329–342/volume:136
info:cnr-pdr/source/autori:Kass-Simon G.1, Pannaccione A.2, Pierobon P.3/titolo:GABA and glutamate receptors are involved in modulating pacemaker activity in hydra/doi:/rivista:/anno:2003/pagina_da:329/pagina_a:342/intervallo_pagine:329–342/volume:136
The effects of gamma-amino butyric acid (GABA) and glutamate, their ionotropic agonists and antagonists on hydra’s ectodermal and endodermal pacemaker systems were studied. GABA decreased ectodermal body contraction bursts (CBs) and the number of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891e17f1ed3505cbb336c8f43223a526
https://pubmed.ncbi.nlm.nih.gov/14511752
https://pubmed.ncbi.nlm.nih.gov/14511752