Zobrazeno 1 - 10
of 1 097
pro vyhledávání: '"LGI1"'
Autor:
Denise Cerne, Federico Massa, Marco Mora, Silvia Morbelli, Luca Roccatagliata, Giacomo Rebella, Flavio Villani, Federica Bozzano, Antonio Uccelli, Luana Benedetti, Corrado Cabona
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39586- (2024)
Autoimmune encephalitis (AE) is an immune-mediated condition that induces brain inflammation due to several neural-specific autoantibodies. The main triggering and predisposing factors are infections, genetics, the use of immune checkpoint inhibitors
Externí odkaz:
https://doaj.org/article/94e7f347348e420fa5f05ab9f94b745c
Autor:
Qianqian Zhang, Wenping Yang, Yun Qian, Yu Zhang, Huihui Zhao, Mingzhu Shu, Qingyang Li, Yanan Li, Yu Ding, Shiyu Shi, Yaxi Liu, Xi Cheng, Qi Niu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAutoimmune encephalitis (AE) comprises a group of inflammatory brain disorders mediated by autoimmune responses. Anti–N-methyl-D-aspartate receptor (NMDAR) encephalitis, anti–leucine-rich glioma-inactivated 1 (LGI1) encephalitis, and
Externí odkaz:
https://doaj.org/article/eb33e227de1e4e28972b8d0e3ea1f25a
Publikováno v:
Annals of Movement Disorders, Vol 7, Iss 1, Pp 35-39 (2024)
Anti-leucine-rich, glioma-inactivated (LGI1) autoimmune encephalitis is one of the autoimmune encephalitides with a distinct movement abnormality – faciobrachial dystonic seizures (FBDS). FBDS, being the clinching sign towards a clinical diagnosis,
Externí odkaz:
https://doaj.org/article/f7c0f54850464a84ab68f98eb951dd11
Autor:
Soon-Tae Lee, Hesham Abboud, Sarosh R. Irani, Hideto Nakajima, Amanda L. Piquet, Sean J. Pittock, E. Ann Yeh, Jiawei Wang, Sharmila Rajan, James Overell, Jillian Smith, Jane St Lambert, Muna El-Khairi, Marina Gafarova, Jeffrey M. Gelfand
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundAutoimmune encephalitis (AIE) encompasses a spectrum of rare autoimmune-mediated neurological disorders, which are characterized by brain inflammation and dysfunction. Autoantibodies targeting the N-methyl-d-aspartic acid receptor (NMDAR) a
Externí odkaz:
https://doaj.org/article/8e934d562b244ba88ff1f00093c8fd1c
Autor:
Jorge Ramirez-Franco, Kévin Debreux, Marion Sangiardi, Maya Belghazi, Yujin Kim, Suk-Ho Lee, Christian Lévêque, Michael Seagar, Oussama El Far
Publikováno v:
Neurobiology of Disease, Vol 196, Iss , Pp 106513- (2024)
In animal models of LGI1-dependent autosomal dominant lateral temporal lobe epilepsy, Kv1 channels are downregulated, suggesting their crucial involvement in epileptogenesis. The molecular basis of Kv1 channel-downregulation in LGI1 knock-out mice ha
Externí odkaz:
https://doaj.org/article/2e7ee02f8fec4a0aa115a578527a6516
Autor:
Gökberk Metin, Özden Kamışlı
Publikováno v:
Archives of Epilepsy, Vol 30, Iss 1, Pp 36-38 (2024)
New-onset refractory status epilepticus (NORSE) is a rare, life-threatening clinical presentation in patients without a known history of epileptic seizures. Autoimmune encephalitis is the most common cause identified in adults; however, in up to 50%
Externí odkaz:
https://doaj.org/article/08a49b9e53d54b69bc99a08723e7ac99
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Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-20 (2023)
Abstract Background Aberrant DNA methylation occurs commonly during pathogenesis of neuroimmunological diseases and is of clinical value in various encephalitis subtypes. However, knowledge of the impact of DNA methylation changes on pathogenesis of
Externí odkaz:
https://doaj.org/article/13c7e6830600437f92663b7e47a692fd
Publikováno v:
Visual Computing for Industry, Biomedicine, and Art, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract This study aims to discriminate between leucine-rich glioma-inactivated 1 (LGI1) antibody encephalitis and gamma-aminobutyric acid B (GABAB) receptor antibody encephalitis using a convolutional neural network (CNN) model. A total of 81 patie
Externí odkaz:
https://doaj.org/article/b66991608cde47ceb0105dd1d2fda379
Publikováno v:
BMC Pediatrics, Vol 23, Iss 1, Pp 1-6 (2023)
Abstract Background LGI-1 antibody-associated encephalitis is a type of autoimmune encephalitis with a lower prevalence than NMDAR antibody-associated encephalitis. LGI-1 antibody-associated encephalitis is the second most prevalent of all autoimmune
Externí odkaz:
https://doaj.org/article/390d74c39f7148f2a468331dd68dbad7