Zobrazeno 1 - 10
of 1 080
pro vyhledávání: '"LGG"'
Autor:
Muhammad Naveed, Sarmad Mahmood, Tariq Aziz, Arooj Azeem, Zeerwah Rajpoot, Shafiq ur Rehman, Fahad Al-Asmari, Amirah S. Alahmari, Ohud Saleh, Manal Y. Sameeh, Majid Alhomrani, Abdulhakeem S. Alamri, Sahar A. Alshareef
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Brain tumors, particularly Glioblastoma Multiforme (GBM) and Low-Grade Gliomas (LGG), present significant clinical challenges due to their aggressive nature and resistance to conventional treatments. Traditional therapies such as surgery, ch
Externí odkaz:
https://doaj.org/article/ddd25fbba94d4715af1ffe41aac5430a
Autor:
Olga Kim, Zach Sergi, Guangyang Yu, Kazutoshi Yamamoto, Martha Quezado, Zied Abdullaev, Danel R. Crooks, Shun Kishimoto, Qi Li, Peng Lu, Burchelle Blackman, Thorkell Andresson, Xiaolin Wu, Bao Tran, Jun S. Wei, Wei Zhang, Meili Zhang, Hua Song, Javed Khan, Murali C. Krishna, Jeffrey R. Brender, Jing Wu
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Malignant transformation (MT) is commonly seen in IDH-mutant gliomas. There has been a growing research interest in revealing its underlying mechanisms and intervening prior to MT at the early stages of the transforming process. Here we esta
Externí odkaz:
https://doaj.org/article/4b329e13fa87456ea2628bbe4d0bfe40
Publikováno v:
Cancer Management and Research, Vol Volume 16, Pp 711-730 (2024)
Li`ao Wang,1 Zhiming Zheng,2 Jia Zheng,2 Guifeng Zhang,3 Zheng Wang4 1Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, 300203, People’s Republic of China; 2Department of Neurosurgery, Shandon
Externí odkaz:
https://doaj.org/article/03dd61dbb44e4a0f8780629331618a81
Autor:
Gu Linazi, Aierpati Maimaiti, Zulihuma Abulaiti, Hui Shi, Zexin Zhou, Mizhati Yimiti Aisa, Yali Kang, Ayguzaili Abulimiti, Xierzhati Dilimulati, Tiecheng Zhang, Patiman Wusiman, Zengliang Wang, Aimitaji Abulaiti
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36989- (2024)
Background: The investigation explores the involvement of anoikis-related genes (ARGs) in lower-grade glioma (LGG), seeking to provide fresh insights into the disease's underlying mechanisms and to identify potential targets for therapy. Methods: We
Externí odkaz:
https://doaj.org/article/81e3629be0f64220a90124fbe9cc15eb
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Low-grade glioma (LGG) is heterogeneous at biological and transcriptomic levels, and it is still controversial for the definition and typing of LGG. Therefore, there is an urgent need for specific and practical molecular signatures for accur
Externí odkaz:
https://doaj.org/article/ac8fbd837d3241458b4cea72ffe70a72
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Low-grade glioma (LGG) is a prevalent and lethal primary brain malignancy, with most patients succumbing to recurrence and progression. The signal transducer and activator of transcription (STAT) family has long been implicated in tumor initiation an
Externí odkaz:
https://doaj.org/article/1978c4131d9b4defaf32a2115aaaec14
Autor:
Peng Gao, Huaixu Li, Yang Qiao, Jianyu Nie, Sheng Cheng, Guozhang Tang, Xingliang Dai, Hongwei Cheng
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32270- (2024)
DLAT has been recognized as a cuproptosis-related gene that is crucial for cuproptosis in earlier research. The study is to look at how DLAT affects individuals with low-grade glioma's prognosis and immune infiltration. The Genotype-Tissue Expression
Externí odkaz:
https://doaj.org/article/b973f44fbdbf455e9748cc622d1c81d1
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-16 (2024)
Abstract Background The WD40 repeat (WDR) domain provides scaffolds for numerous protein–protein interactions in multiple biological processes. WDR domain 76 (WDR76) has complex functionality owing to its diversified interactions; however, its mech
Externí odkaz:
https://doaj.org/article/654eab61152d48dbb4dd1035a2b2b91f
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/ed49ed46fb5a412b9cce1878aaa4e0d7
Autor:
Sana Munquad, Asim Bikas Das
Publikováno v:
BioData Mining, Vol 16, Iss 1, Pp 1-18 (2023)
Abstract Background and objective The classification of glioma subtypes is essential for precision therapy. Due to the heterogeneity of gliomas, the subtype-specific molecular pattern can be captured by integrating and analyzing high-throughput omics
Externí odkaz:
https://doaj.org/article/1058e325ebba4e8bb3647977518a700e