Zobrazeno 1 - 10
of 41
pro vyhledávání: '"LETICIA V. COSTA-LOTUFO"'
Autor:
Luis Carlos Chitiva, Paula Rezende-Teixeira, Tiago F. Leão, Hair Santiago Lozano-Puentes, Ximena Londoño, Lucía Ana Díaz-Ariza, Leticia V. Costa-Lotufo, Juliet A. Prieto-Rodríguez, Geison M. Costa, Ian Castro-Gamboa
Publikováno v:
ACS Omega, Vol 9, Iss 35, Pp 36939-36960 (2024)
Externí odkaz:
https://doaj.org/article/43d21f0f671848efa07dcc3bc56c8988
Autor:
Luis Carlos Chitiva, Mary Andrea Santamaría-Torres, Paula Rezende-Teixeira, Jessica Rodrigues Pereira de Oliveira Borlot, Rodrigo de Almeida Romagna, Ximena Londoño, Rodrigo Rezende Kitagawa, Leticia V. Costa-Lotufo, Juliet A. Prieto-Rodríguez, Ian Castro-Gamboa, Geison Modesti Costa
Publikováno v:
Molecules, Vol 29, Iss 13, p 2985 (2024)
Metabolic alterations are increasingly recognized as important aspects of colorectal cancer (CRC), offering potential avenues for identifying therapeutic targets. Previous studies have demonstrated the cytotoxic potential of bamboo leaf extract obtai
Externí odkaz:
https://doaj.org/article/70b45431e1544033a4bfab95055b0959
Autor:
Vanessa Franco Carvalho Dartora, Julia S. Passos, Leticia V. Costa-Lotufo, Luciana B. Lopes, Alyssa Panitch
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 231 (2024)
Despite advances in breast cancer treatment, there remains a need for local management of noninvasive, low-grade ductal carcinoma in situ (DCIS). These focal lesions are well suited for local intraductal treatment. Intraductal administration supporte
Externí odkaz:
https://doaj.org/article/d8614311b16346c0b624f3fd6b810dc3
Autor:
Rodolfo H. V. Nishimura, Thiago dos Santos, Valter E. Murie, Luciana C. Furtado, Leticia V. Costa-Lotufo, Giuliano C. Clososki
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 2968-2975 (2021)
Microwave-mediated N-arylation of 4-chloroquinazolines in THF/H2O rapidly and efficiently afforded a library of novel 6-halo-2-phenyl-substituted 4-anilinoquinazolines. The methodology was compatible with numerous ortho-, meta-, and para-substituted
Externí odkaz:
https://doaj.org/article/613ac7356a4844688198ee5ded857271
Autor:
Évila Pinheiro Damasceno, Ives Charlie-Silva, Glaucia Maria Machado-Santelli, Anali M.B. Garnique, João Agostinho Machado-Neto, Simone Aparecida Teixeira, Paula C. Jimenez, Diana Carneiro, Amadeu M.V.M. Soares, Leticia V. Costa-Lotufo, Susana Loureiro, Maria D. Pavlaki
Publikováno v:
Environmental Advances, Vol 8, Iss , Pp 100208- (2022)
Anticancer agents pose a great environmental risk due to their high toxicity. The aim of the current study is to assess the toxicity of trabectedin, a cytotoxic but atypical DNA binder, to liver cell line (ZFL) and embryo-larvae of the zebrafish Dani
Externí odkaz:
https://doaj.org/article/d18b5e5ab6c2414f92ed3d92b90d31a2
Autor:
Luqmaan Mohamed, Suparna Chakraborty, K.N. ArulJothi, Lawrence Mabasa, Kenza Sayah, Leticia V. Costa-Lotufo, Anwar Jardine, Sharon Prince
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 10, Pp 1155-1165 (2020)
Globally, breast cancer is the most common malignancy in women and the second most common cause of cancer-related death among women. There is therefore a need to identify more efficacious therapies for this neoplasm. Galenia africana (Kraalbos) is a
Externí odkaz:
https://doaj.org/article/d6fc4571746f4b6b94b6568d7f3da7b8
Autor:
Rodrigo dos A. Miguel, Amanda S. Hirata, Paula C. Jimenez, Luciana B. Lopes, Leticia V. Costa-Lotufo
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1722 (2022)
Nature is the largest pharmacy in the world. Doxorubicin (DOX) and paclitaxel (PTX) are two examples of natural-product-derived drugs employed as first-line treatment of various cancer types due to their broad mechanisms of action. These drugs are ma
Externí odkaz:
https://doaj.org/article/6ef0b5c6a7414b3486f4d79623ba8322
Autor:
Luciana C. Furtado, Anelize Bauermeister, Rafael de Felicio, Raquel Ortega, Francisco das Chagas L. Pinto, João Agostinho Machado-Neto, Daniela B. B. Trivella, Otilia D. L. Pessoa, Diego V. Wilke, Norberto P. Lopes, Paula C. Jimenez, Leticia V. Costa-Lotufo
Publikováno v:
Frontiers in Marine Science, Vol 8 (2021)
Marine natural products have emerged as an important source for drug development, notably in the field of anticancer therapy. Still, the limited effectiveness of current therapies for central nervous system tumors indicates the need to identify new t
Externí odkaz:
https://doaj.org/article/da03da7363c242db89ff2392d200158b
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 92, Iss 1 (2020)
Abstract Pharmaceuticals occur in the environment due to their excessive consumption and the inefficiency of treatment plants to degrade, inactivate or remove them. Diazepam (DZP) stands out as the most consumed benzodiazepine, and induces sedative e
Externí odkaz:
https://doaj.org/article/74a907847ba348548171ac9ad51c9957
Autor:
Bianca Del B. Sahm, Jade Peres, Paula Rezende-Teixeira, Evelyne A. Santos, Paola C. Branco, Anelize Bauermeister, Serah Kimani, Eduarda A. Moreira, Renata Bisi-Alves, Claire Bellis, Mihlali Mlaza, Paula C. Jimenez, Norberto P. Lopes, Glaucia M. Machado-Santelli, Sharon Prince, Leticia V. Costa-Lotufo
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
The TBX2 transcription factor plays critical roles during embryonic development and it is overexpressed in several cancers, where it contributes to key oncogenic processes including the promotion of proliferation and bypass of senescence. Importantly
Externí odkaz:
https://doaj.org/article/73482a0c96654764b516582950463422