Zobrazeno 1 - 10
of 53
pro vyhledávání: '"LESLIE SH"'
Autor:
Rosemary J. Jackson, Alexandra Melloni, Dustin P. Fykstra, Alberto Serrano-Pozo, Leslie Shinobu, Bradley T. Hyman
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract Progressive supranuclear palsy (PSP) is a neurodegenerative disease characterized by 4R tau deposition in neurons as well as in astrocytes and oligodendrocytes. While astrocytic tau deposits are rarely observed in normal aging (so-called agi
Externí odkaz:
https://doaj.org/article/7ddead6245bf458baa493a99e4bcebbf
Autor:
David A. Johnson, Amisha M. Parikh-Das, Evren Atillasoy, Hayk Davtyan, Leslie Shur, Andrea S. Blevins-Primeau, Nathaniel F. Watson
Publikováno v:
Exploration of Medicine, Vol 4, Iss 6, Pp 1014-1025 (2023)
Nocturnal heartburn (NHB) is a symptom that affects up to 25% of the general population and has been shown to cause sleep disruption that adversely affects quality of life and psychomotor performance. Few studies have evaluated the association betwee
Externí odkaz:
https://doaj.org/article/426a0b29abbf496598c47ad00581918e
Autor:
Lin Li, Esther Gupta, John Spaeth, Leslie Shing, Rafael Jaimes, Emily Engelhart, Randolph Lopez, Rajmonda S. Caceres, Tristan Bepler, Matthew E. Walsh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Therapeutic antibodies are an important and rapidly growing drug modality. However, the design and discovery of early-stage antibody therapeutics remain a time and cost-intensive endeavor. Here we present an end-to-end Bayesian, language mod
Externí odkaz:
https://doaj.org/article/4b310d77320b4b48bba9cd5498b95743
Autor:
Leslie Shelton, Aubree Hughart-Thomas
Publikováno v:
Journal of College Orientation, Transition, and Retention, Vol 30, Iss 2 (2023)
The research questions that guided this study were: What are undocumented college students’ experiences with orientation, transition, and retention (OTR) efforts on campus? How do undocumented students perceive their OTR experiences relate to their
Externí odkaz:
https://doaj.org/article/d1ad9ec04acd4fe6ba77c4c9395683b2
Autor:
Emily Engelhart, Ryan Emerson, Leslie Shing, Chelsea Lennartz, Daniel Guion, Mary Kelley, Charles Lin, Randolph Lopez, David Younger, Matthew E. Walsh
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-8 (2022)
Measurement(s) Antibody Binding Technology Type(s) AlphaSeq Factor Type(s) Antibody sequence Sample Characteristic - Organism Homo sapiens
Externí odkaz:
https://doaj.org/article/7ed73458fda2470ca8688623100f439b
Autor:
Ellen T. Weber, Carla P. Catterall, John Locke, Liz S. Ota, Bruce Prideaux, Leslie Shirreffs, Leah Talbot, Iain J. Gordon
Publikováno v:
Earth, Vol 2, Iss 2, Pp 248-271 (2021)
World Heritage is the pinnacle of the recognition of the natural, aesthetic, and cultural value of a place on the planet. Since its inception in 1972, over 1100 sites have received World Heritage status. Many of these places are being challenged by t
Externí odkaz:
https://doaj.org/article/91aa3a7dc0534663b8b2223deaea2c2a
Publikováno v:
Palliative Medicine Reports, Vol 1, Iss 1, Pp 264-269 (2020)
Background: Individuals experiencing homelessness face marginalization, dehumanization, and barriers to accessing quality palliative care. Inspired by the 3 Wishes Project, the Good Wishes Project (GWP) facilitates granting wishes to individuals expe
Externí odkaz:
https://doaj.org/article/bc9a5ecabf91435abb9102ead2bdd7e6
Autor:
Nicolai Franzmeier, M. Suárez-Calvet, Lukas Frontzkowski, Annah Moore, Timothy J. Hohman, Estrella Morenas-Rodriguez, Brigitte Nuscher, Leslie Shaw, John Q. Trojanowski, Martin Dichgans, Gernot Kleinberger, Christian Haass, Michael Ewers, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Background The Apolipoprotein E ε4 allele (i.e. ApoE4) is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD). TREM2 (i.e. Triggering receptor expressed on myeloid cells 2) is a microglial transmembrane protein brain t
Externí odkaz:
https://doaj.org/article/e39dd285d82e4f3297682ed1c4da700a
Autor:
Michael Ewers, Gloria Biechele, Marc Suárez‐Calvet, Christian Sacher, Tanja Blume, Estrella Morenas‐Rodriguez, Yuetiva Deming, Laura Piccio, Carlos Cruchaga, Gernot Kleinberger, Leslie Shaw, John Q Trojanowski, Jochen Herms, Martin Dichgans, the Alzheimer's Disease Neuroimaging Initiative (ADNI), Matthias Brendel, Christian Haass, Nicolai Franzmeier
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 9, Pp 1-14 (2020)
Abstract Microglia activation is the brain's major immune response to amyloid plaques in Alzheimer's disease (AD). Both cerebrospinal fluid (CSF) levels of soluble TREM2 (sTREM2), a biomarker of microglia activation, and microglia PET are increased i
Externí odkaz:
https://doaj.org/article/9500415c117547ba868021c5c4d1ca2c
Autor:
Lina Franco, Ana de Matos, Mario Abrantes, Zachary Tacner, Leslie Sharp, Wazir Abdullahi, Christopher Fraser, Heather Hrach, Nicole Grigaitis
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/eaa35adeb8734a3086dae3731a2c5082