Zobrazeno 1 - 10
of 21 719
pro vyhledávání: '"LESLIE J"'
Autor:
Rinki Kumar, Rebecca Kaddis Maldonado, Neil D. Christensen, Maria C. Bewley, John M. Flanagan, Nicholas J. Buchkovich, Leslie J. Parent
Publikováno v:
COVID, Vol 4, Iss 9, Pp 1338-1354 (2024)
Human coronavirus 229E (HCoV-229E) is an alpha coronavirus that infects humans and bats. In common with all positive-strand RNA viruses, 229E infection causes rearrangements of the host’s intracellular membranes to form replication organelles, a hi
Externí odkaz:
https://doaj.org/article/dd85e27d05c04e1b820da13dff73191c
Autor:
Gregory S. Lambert, Breanna L. Rice, Rebecca J. Kaddis Maldonado, Jordan Chang, Leslie J. Parent
Publikováno v:
Retrovirology, Vol 21, Iss 1, Pp 1-31 (2024)
Abstract Retroviruses exploit host proteins to assemble and release virions from infected cells. Previously, most studies focused on interacting partners of retroviral Gag proteins that localize to the cytoplasm or plasma membrane. Given that several
Externí odkaz:
https://doaj.org/article/23eb809c631e4abfbaa5a37679f9d439
Autor:
Lisa K. Randolph, Michaela M. Pauers, José C. Martínez, Leslie J. Sibener, Michael A. Zrzavy, Nyle A. Sharif, Tatiana M. Gonzalez, Kapil V. Ramachandran, Daniel Dominguez, Ulrich Hengst
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114747- (2024)
Summary: The formation, stabilization, and elimination of synapses are tightly regulated during neural development and into adulthood. Pumilio RNA-binding proteins regulate the translation and localization of many synaptic mRNAs and are developmental
Externí odkaz:
https://doaj.org/article/8f996393a99b4a039d1d35ce57eed479
Autor:
Jonathan P. Bradfeld, Rachel L. Kember, Anna Ulrich, Zhanna Balkhiyarova, Akram Alyass, Izzuddin M. Aris, Joshua A. Bell, K. Alaine Broadaway, Zhanghua Chen, Jin-Fang Chai, Neil M. Davies, Dietmar Fernandez-Orth, Mariona Bustamante, Ruby Fore, Amitavo Ganguli, Anni Heiskala, Jouke-Jan Hottenga, Carmen Íñiguez, Sayuko Kobes, Jaakko Leinonen, Estelle Lowry, Leo-Pekka Lyytikainen, Anubha Mahajan, Niina Pitkänen, Theresia M. Schnurr, Christian Theil Have, David P. Strachan, Elisabeth Thiering, Suzanne Vogelezang, Kaitlin H. Wade, Carol A. Wang, Andrew Wong, Louise Aas Holm, Alessandra Chesi, Catherine Choong, Miguel Cruz, Paul Elliott, Steve Franks, Christine Frithiof-Bøjsøe, W. James Gauderman, Joseph T. Glessner, Vicente Gilsanz, Kendra Griesman, Robert L. Hanson, Marika Kaakinen, Heidi Kalkwarf, Andrea Kelly, Joseph Kindler, Mika Kähönen, Carla Lanca, Joan Lappe, Nanette R. Lee, Shana McCormack, Frank D. Mentch, Jonathan A. Mitchell, Nina Mononen, Harri Niinikoski, Emily Oken, Katja Pahkala, Xueling Sim, Yik-Ying Teo, Leslie J. Baier, Toos van Beijsterveldt, Linda S. Adair, Dorret I. Boomsma, Eco de Geus, Mònica Guxens, Johan G. Eriksson, Janine F. Felix, Frank D. Gilliland, Penn Medicine Biobank, Torben Hansen, Rebecca Hardy, Marie-France Hivert, Jens-Christian Holm, Vincent W. V. Jaddoe, Marjo-Riitta Järvelin, Terho Lehtimäki, David A. Mackey, David Meyre, Karen L. Mohlke, Juha Mykkänen, Sharon Oberfeld, Craig E. Pennell, John R. B. Perry, Olli Raitakari, Fernando Rivadeneira, Seang-Mei Saw, Sylvain Sebert, John A. Shepherd, Marie Standl, Thorkild I. A. Sørensen, Nicholas J. Timpson, Maties Torrent, Gonneke Willemsen, Elina Hypponen, Chris Power, The Early Growth Genetics Consortium, Mark I. McCarthy, Rachel M. Freathy, Elisabeth Widén, Hakon Hakonarson, Inga Prokopenko, Benjamin F. Voight, Babette S. Zemel, Struan F. A. Grant, Diana L. Cousminer
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/e9448135c0a94a80bb3b73a022f181ed
Autor:
Sam Mostafa, Reza Rafizadeh, Thomas M. Polasek, Chad A. Bousman, Amin Rostami‐Hodjegan, Robert Stowe, Prescilla Carrion, Leslie J. Sheffield, Carl M. J. Kirkpatrick
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 3, Pp 424-436 (2024)
Abstract Model‐informed precision dosing using virtual twins (MIPD‐VTs) is an emerging strategy to predict target drug concentrations in clinical practice. Using a high virtualization MIPD‐VT approach (Simcyp version 21), we predicted the stead
Externí odkaz:
https://doaj.org/article/7d8f3b86d1004aa6a7d17a743b344511
Autor:
Tatiana C. Coverdell, Maureen Sampson, Rafael Zubirán, Anna Wolska, Leslie J. Donato, Jeff W. Meeusen, Allan S. Jaffe, Alan T. Remaley
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background The accurate measurement of Low-density lipoprotein cholesterol (LDL-C) is critical in the decision to utilize the new lipid-lowering therapies like PCSK9-inhibitors (PCSK9i) for high-risk cardiovascular disease patients that do n
Externí odkaz:
https://doaj.org/article/7403eba74a3b4bc1aba9f686e7990b06
Autor:
Haotian Yang, Haolu Wang, Yaowu He, Yang Yang, Erik W. Thompson, Di Xia, Leslie J. Burke, Lu Cao, John D. Hooper, Michael S. Roberts, Darrell H.G. Crawford, Xiaowen Liang
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114512- (2024)
Summary: Tumor self-seeding is a process whereby circulating tumor cells (CTCs) recolonize the primary tumor, which promotes tumor growth, angiogenesis, and invasion. However, the detailed nature and functions of tumor self-seeded cells (TSCs) have n
Externí odkaz:
https://doaj.org/article/fa23ece730fa40808441c6485d490966
A machine learning approach feature to forecast the future performance of the universities in Canada
Publikováno v:
Machine Learning with Applications, Vol 16, Iss , Pp 100548- (2024)
University ranking is a technique of measuring the performance of Higher Education Institutions (HEIs) by evaluating them on various criteria like student satisfaction, expenditure, research and teaching quality, citation count, grants, and enrolment
Externí odkaz:
https://doaj.org/article/32ebed613d4348aabcdd5fab70bc7e86
Publikováno v:
HTS Teologiese Studies/Theological Studies, Vol 80, Iss 1, Pp e1-e10 (2024)
Two conceptual strands of research within the field of cathedral studies have theorised the capacity of Anglican cathedrals to engage more successfully than parish churches with the wider non-churchgoing community. One strand has explored mobilising
Externí odkaz:
https://doaj.org/article/2b8bde5c79f44687b9bf63a15c3bf947
Autor:
Jonathan P. Bradfield, Rachel L. Kember, Anna Ulrich, Zhanna Balkhiyarova, Akram Alyass, Izzuddin M. Aris, Joshua A. Bell, K. Alaine Broadaway, Zhanghua Chen, Jin-Fang Chai, Neil M. Davies, Dietmar Fernandez-Orth, Mariona Bustamante, Ruby Fore, Amitavo Ganguli, Anni Heiskala, Jouke-Jan Hottenga, Carmen Íñiguez, Sayuko Kobes, Jaakko Leinonen, Estelle Lowry, Leo-Pekka Lyytikainen, Anubha Mahajan, Niina Pitkänen, Theresia M. Schnurr, Christian Theil Have, David P. Strachan, Elisabeth Thiering, Suzanne Vogelezang, Kaitlin H. Wade, Carol A. Wang, Andrew Wong, Louise Aas Holm, Alessandra Chesi, Catherine Choong, Miguel Cruz, Paul Elliott, Steve Franks, Christine Frithioff-Bøjsøe, W. James Gauderman, Joseph T. Glessner, Vicente Gilsanz, Kendra Griesman, Robert L. Hanson, Marika Kaakinen, Heidi Kalkwarf, Andrea Kelly, Joseph Kindler, Mika Kähönen, Carla Lanca, Joan Lappe, Nanette R. Lee, Shana McCormack, Frank D. Mentch, Jonathan A. Mitchell, Nina Mononen, Harri Niinikoski, Emily Oken, Katja Pahkala, Xueling Sim, Yik-Ying Teo, Leslie J. Baier, Toos van Beijsterveldt, Linda S. Adair, Dorret I. Boomsma, Eco de Geus, Mònica Guxens, Johan G. Eriksson, Janine F. Felix, Frank D. Gilliland, Penn Medicine Biobank, Torben Hansen, Rebecca Hardy, Marie-France Hivert, Jens-Christian Holm, Vincent W. V. Jaddoe, Marjo-Riitta Järvelin, Terho Lehtimäki, David A. Mackey, David Meyre, Karen L. Mohlke, Juha Mykkänen, Sharon Oberfield, Craig E. Pennell, John R. B. Perry, Olli Raitakari, Fernando Rivadeneira, Seang-Mei Saw, Sylvain Sebert, John A. Shepherd, Marie Standl, Thorkild I. A. Sørensen, Nicholas J. Timpson, Maties Torrent, Gonneke Willemsen, Elina Hypponen, Chris Power, The Early Growth Genetics Consortium, Mark I. McCarthy, Rachel M. Freathy, Elisabeth Widén, Hakon Hakonarson, Inga Prokopenko, Benjamin F. Voight, Babette S. Zemel, Struan F. A. Grant, Diana L. Cousminer
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Pubertal growth patterns correlate with future health outcomes. However, the genetic mechanisms mediating growth trajectories remain largely unknown. Here, we modeled longitudinal height growth with Super-Imposition by Translation
Externí odkaz:
https://doaj.org/article/01f378c433c944aea3f99eb2232d6404