Zobrazeno 1 - 10
of 140
pro vyhledávání: '"LEON I. GOLDBERG"'
Publikováno v:
Journal of Cardiothoracic and Vascular Anesthesia. 5:29-32
The authors compared the systemic hemodynamic and renal vascular effects of hypotension induced by fenoldopam with those produced by the most commonly used hypotensive agent, sodium nitroprusside, in 10 dogs. Mean arterial pressure decreased 26% +/-
Publikováno v:
European Journal of Pharmacology. 187:87-95
Effects of fluorine (F) substitution on the 2- and 6-positions of the catechol ring of epinephrine (Epi) on its alpha- and beta-adrenoceptor agonist activities were studied in anesthetized dogs. Increments in heart rate and contractile force were use
Publikováno v:
Canadian Journal of Anaesthesia. 37:380-384
The introduction of drugs that could induce hypotension with different pharmacological actions would be advantageous because side effects unique to a specific drug could be minimized by selecting appropriate therapy. Specific dopamine-1, (DA1) and do
Publikováno v:
Cancer chemotherapy and pharmacology. 42(4)
Purpose: Morphine can have either an emetic or an antiemetic effect. The emetic effect of morphine can be blocked by methylnaltrexone (MNTX), a quaternary opioid antagonist with peripheral action. In this study, we tested the hypothesis that administ
Publikováno v:
Progress in Cardiovascular Diseases. 19:327-340
T HE pharmacology and clinical uses of dopamine were reviewed in this journal in 1969.’ At that time, only a few therapeutic investigations had been completed, and the clinical literature was sparse. Since dopamine has now been administered to larg
Autor:
Alan S. Bass, Leon I. Goldberg
Publikováno v:
The American Journal of Cardiology. 62:37C-40C
Studies in our laboratory have confirmed that dopexamine hydrochloride is a potent beta 2-adrenoceptor and DA1-dopamine receptor agonist. We examined the effects of dopexamine hydrochloride on both cardiac contractile force, determined by use of a Wa
Autor:
Leon I. Goldberg
Publikováno v:
New England Journal of Medicine. 291:707-710
THE third endogenous catecholamine, dopamine, has been extensively investigated in recent years. Dopamine, the immediate precursor of norepinephrine, is found in high concentrations in sympathetic ...
Publikováno v:
Journal of Cardiovascular Pharmacology. 11:123-126
Relative DA1-dopamine-receptor agonist and alpha-adrenoceptor antagonist activities of fenoldopam were determined in pentobarbital anesthetized dogs. The renal vasodilating effect of intravenous infusions of fenoldopam was used as an index of its DA1
Autor:
Leon I. Goldberg
Publikováno v:
Proceedings of the Royal Society of Medicine. 70:7-15
Autor:
Leon I. Goldberg
Publikováno v:
Journal of Clinical Anesthesia. 1:66-74
Division of dopamine (DA) receptors and alpha- and beta-adrenoceptors into two subtypes provides a pharmacological basis for the clinical use of DA and new DA receptor agonists in anesthesia and critical care medicine. First, differential receptor ac