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pro vyhledávání: '"LENZILUMAB"'
Akademický článek
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Autor:
Dana M. Harris, Jose Valery, Launia J. White, Mohamed Omer, Claudia R. Libertin, Fernando F. Stancampiano, Michael G. Heckman
Publikováno v:
Southern Medical Journal
Multiple systemic abnormalities have been described in patients with coronavirus disease 2019, including various degrees of cardiovascular involvement ranging from mild myocarditis to severe pulmonary hypertension, ventricular dysfunction, and arrhyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de936fc96d85bc638c9bd8b07fb8a5a4
http://europepmc.org/articles/PMC8231014
http://europepmc.org/articles/PMC8231014
Publikováno v:
Leukemia. 35:2739-2751
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping features of myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN). Median overall survival of this aggressive myeloid malignancy is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a65a167c938268672f2ee628c927558c
https://doi.org/10.1038/s41375-021-01330-1
https://doi.org/10.1038/s41375-021-01330-1
Autor:
Andrew D. Badley, Dale Chappell, Colleen F. Kelley, Gabrielle Chappell, Jason V. Baker, Victoria Catterson, Robert Orenstein, Omar J. Ahmed, Claudia R. Libertin, Vincent C. Marconi, Cameron Durrant, Charles D. Burger, Zelalem Temesgen, William Aronstein, Christopher Polk
Publikováno v:
Chest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c6ebea9e73c522cd67198b4ac24bdc
https://doi.org/10.1016/j.chest.2021.08.029
https://doi.org/10.1016/j.chest.2021.08.029
Publikováno v:
Mayo Clinic Proceedings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c270f470fecd2de70bd4329fd8c73b5
http://hdl.handle.net/10281/308134
http://hdl.handle.net/10281/308134
Publikováno v:
Mayo Clinic Proceedings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1503a2e51cf5c4304d4f53e0ec2b1153
https://pubmed.ncbi.nlm.nih.gov/33673929
https://pubmed.ncbi.nlm.nih.gov/33673929
Autor:
Michael Smerina, Pramod Guru, Joshua Propst, Julio C. Mendez, Megan Melody, Jared Nelson, Jacquelyn Hastings
Publikováno v:
Immunotherapy
Background: Coronavirus disease 2019 (COVID-19) is a novel disease associated with a cytokine-mediated, severe, acute respiratory syndrome. Tocilizumab and lenzilumab are recombinant monoclonal antibodies against IL-6 and granulocyte macrophage colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47a45540f68f6db88655a00c6a70945
https://pubmed.ncbi.nlm.nih.gov/32546029
https://pubmed.ncbi.nlm.nih.gov/32546029
Autor:
Reona Sakemura, Bharath Raj Palraj, Mariam Assi, Cameron Durrant, Charles D. Burger, Brian Pickering, Hugo E. Vargas, Robert Orenstein, Zelalem Temesgen, Claudia R. Libertin, Saad S. Kenderian, Ala S. Dababneh, Raymund R. Razonable, Gabrielle Chappell, Dale Chappell, Philippe R. Bauer, Paschalis Vergidis, Omar J. Ahmed, Stacey A. Rizza, Andrew D. Badley
BackgroundIn COVID-19, high levels of granulocyte macrophage-colony stimulating factor (GM-CSF) and inflammatory myeloid cells correlate with disease severity, cytokine storm, and respiratory failure. With this rationale, we used lenzilumab, an anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b11d3316aba1669d71bf00958b18fcf
https://doi.org/10.1101/2020.06.08.20125369
https://doi.org/10.1101/2020.06.08.20125369
Autor:
Traci Kruer, Naseema Gangat, Darci Zblewski, Moritz Binder, Ayalew Tefferi, Rami S. Komrokji, Aref Al-Kali, Hannah Newman, Mrinal M. Patnaik, Cameron Durrant, Abhishek A. Mangaonkar, David A. Sallman, Christopher Letson, Eric Padron, Alan F. List, Maria E. Balasis, Ted Shih, Rachel Heuer, Jeffery Hirvela, Adrian Lo
Publikováno v:
Blood
In this phase 1 trial, inhibition of granulocyte-macrophage colony-stimulating factor (GM-CSF) was associated with clinically meaningful responses in 5 of 15 patients with relapsed or refractory chronic myelomonocytic leukemia (CMML). Preliminary dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ac9dae8cdc999bbf122a368a3a4e8d
https://pubmed.ncbi.nlm.nih.gov/32294158
https://pubmed.ncbi.nlm.nih.gov/32294158
Publikováno v:
Blood. 138:1758-1758
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive sub-type of non-Hodgkin's lymphoma(Liu, et al. Am J Hematol 2019). All three approved CD19-directed CAR-T therapies (axicabtagene ciloleucel, tisagenlecleucel, lisocabtag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcad0a3fc4c119af8b3563ce0dfe0311
https://doi.org/10.1182/blood-2021-153987
https://doi.org/10.1182/blood-2021-153987