Zobrazeno 1 - 10
of 393
pro vyhledávání: '"LE XUAN TRUONG"'
Autor:
Yi Zhang, Miso Park, Lucy Y. Ghoda, Dandan Zhao, Melissa Valerio, Ebtesam Nafie, Asaul Gonzalez, Kevin Ly, Bea Parcutela, Hyeran Choi, Xubo Gong, Fang Chen, Kaito Harada, Zhenhua Chen, Le Xuan Truong Nguyen, Flavia Pichiorri, Jianjun Chen, Joo Song, Stephen J. Forman, Idoroenyi Amanam, Bin Zhang, Jie Jin, John C. Williams, Guido Marcucci
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-18 (2024)
Abstract Background The interleukin-1 receptor accessory protein (IL1RAP) is highly expressed on acute myeloid leukemia (AML) bulk blasts and leukemic stem cells (LSCs), but not on normal hematopoietic stem cells (HSCs), providing an opportunity to t
Externí odkaz:
https://doaj.org/article/81c6c4a1c88f4c5d9d2eee24813cc8c0
Autor:
Bin Zhang, Dandan Zhao, Fang Chen, David Frankhouser, Huafeng Wang, Khyatiben V. Pathak, Lei Dong, Anakaren Torres, Krystine Garcia-Mansfield, Yi Zhang, Dinh Hoa Hoang, Min-Hsuan Chen, Shu Tao, Hyejin Cho, Yong Liang, Danilo Perrotti, Sergio Branciamore, Russell Rockne, Xiwei Wu, Lucy Ghoda, Ling Li, Jie Jin, Jianjun Chen, Jianhua Yu, Michael A. Caligiuri, Ya-Huei Kuo, Mark Boldin, Rui Su, Piotr Swiderski, Marcin Kortylewski, Patrick Pirrotte, Le Xuan Truong Nguyen, Guido Marcucci
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract The mechanisms underlying the transformation of chronic myeloid leukemia (CML) from chronic phase (CP) to blast crisis (BC) are not fully elucidated. Here, we show lower levels of miR-142 in CD34+CD38− blasts from BC CML patients than in t
Externí odkaz:
https://doaj.org/article/883dc5faaf3c4abe8121ce71d3dc31ce
Publikováno v:
Electronic Journal of Qualitative Theory of Differential Equations, Vol 2022, Iss 55, Pp 1-21 (2022)
This work deals with the following viscoelastic heat equations with logarithmic nonlinearity \begin{align*} u_t-\Delta u+\int_{0}^{t}g(t-s)\Delta u(s)ds=\vert u\vert^{p-2}u\ln\vert u\vert. \end{align*} In this paper, we show the effects of the visco
Externí odkaz:
https://doaj.org/article/a538831e7c0449918ec86b5912563086
Autor:
Lianjun Zhang, Le Xuan Truong Nguyen, Ying-Chieh Chen, Dijiong Wu, Guerry J. Cook, Dinh Hoa Hoang, Casey J. Brewer, Xin He, Haojie Dong, Shu Li, Man Li, Dandan Zhao, Jing Qi, Wei-Kai Hua, Qi Cai, Emily Carnahan, Wei Chen, Xiwei Wu, Piotr Swiderski, Russell C. Rockne, Marcin Kortylewski, Ling Li, Bin Zhang, Guido Marcucci, Ya-Huei Kuo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
miR-126 is highly expressed in inv(16) Acute myeloid leukemia (AML) but its role is unclear. Here, the authors show that the aberrant expression of miR-126 in inv(16) AML is directly due to the CBFB-MYH11 fusion gene and that it can promote AML devel
Externí odkaz:
https://doaj.org/article/ba8150db19cd424e95fcc1bef2ef61ff
Autor:
Bin Zhang, Le Xuan Truong Nguyen, Dandan Zhao, David E. Frankhouser, Huafeng Wang, Dinh Hoa Hoang, Junjing Qiao, Christina Abundis, Matthew Brehove, Yu-Lin Su, Yuxin Feng, Anthony Stein, Lucy Ghoda, Adrianne Dorrance, Danilo Perrotti, Zhen Chen, Anjia Han, Flavia Pichiorri, Jie Jin, Tijana Jovanovic-Talisman, Michael A. Caligiuri, Calvin J. Kuo, Akihiko Yoshimura, Ling Li, Russell C. Rockne, Marcin Kortylewski, Yi Zheng, Nadia Carlesso, Ya-Huei Kuo, Guido Marcucci
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-19 (2021)
Abstract Background During acute myeloid leukemia (AML) growth, the bone marrow (BM) niche acquires significant vascular changes that can be offset by therapeutic blast cytoreduction. The molecular mechanisms of this vascular plasticity remain to be
Externí odkaz:
https://doaj.org/article/52f9905cc5f14aa08a70fe465bcdd2b1
Autor:
Ralf Buettner, Le Xuan Truong Nguyen, Corey Morales, Min-Hsuan Chen, Xiwei Wu, Lisa S. Chen, Dinh Hoa Hoang, Servando Hernandez Vargas, Vinod Pullarkat, Varsha Gandhi, Guido Marcucci, Steven T. Rosen
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-16 (2021)
Abstract Background BCL‐2 inhibition through venetoclax (VEN) targets acute myeloid leukemia (AML) blast cells and leukemic stem cells (LSCs). Although VEN-containing regimens yield 60–70% clinical response rates, the vast majority of patients in
Externí odkaz:
https://doaj.org/article/79107741b5c5447d8ccfb700eb63b9aa
Autor:
Dinh Hoa Hoang, Ralf Buettner, Melissa Valerio, Lucy Ghoda, Bin Zhang, Ya-Huei Kuo, Steven T. Rosen, John Burnett, Guido Marcucci, Vinod Pullarkat, Le Xuan Truong Nguyen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6568 (2022)
Venetoclax (VEN) in combination with hypomethylating agents induces disease remission in patients with de novo AML, however, most patients eventually relapse. AML relapse is attributed to the persistence of drug-resistant leukemia stem cells (LSCs).
Externí odkaz:
https://doaj.org/article/92c695ef54d44e219c2297bb7f79b30e
Publikováno v:
Electronic Journal of Differential Equations, Vol 2018, Iss 187,, Pp 1-14 (2018)
The purpose of this article is to establish the molecular decomposition of the homogeneous Besov-Morrey spaces associated with the Hermite operator $\mathbb{H} = -\Delta+|x|^2$ on the Euclidean space $\mathbb{R}^n$. Particularly, we obtain some es
Externí odkaz:
https://doaj.org/article/e768a9952ad847b1b4ec08c665b2453e
Autor:
Nhan Le, Le Xuan Truong
Publikováno v:
Electronic Journal of Qualitative Theory of Differential Equations, Vol 2018, Iss 67, Pp 1-25 (2018)
In this paper, we study an initial-boundary value problem for a doubly nonlinear diffusion equation with logarithmic nonlinearity. By using the potential well method, we give some threshold results on existence or nonexistence of global weak solution
Externí odkaz:
https://doaj.org/article/b5a84d668c3c4690b3c6af4a80825721
Autor:
Le Xuan Truong, Le Cong Nhan
Publikováno v:
Electronic Journal of Differential Equations, Vol 2016, Iss 206,, Pp 1-17 (2016)
This work concerns the multi-point nonlinear Neumann boundary-value problem involving a p-Laplacian-like operator $$\displaylines{ (\phi( u'))' = f(t, u, u'),\quad t\in (0,1), \cr u'(0) = u'(\eta), \quad \phi(u'(1)) = \sum_{i=1}^m{\alpha_i \phi(u
Externí odkaz:
https://doaj.org/article/3a3bd9c1484d4c3ca63bafecc9ab0df5