Sphingosine-1-phosphate (S1P) receptor type 1 signaling in macrophages reduces atherosclerosis in LDL receptor-deficient mice.

Autor: Potì F; Department of Medicine and Surgery - Unit of Neurosciences, University of Parma, Parma, Italy., Scalera E; Department of Food and Drug, University of Parma, Parma, Italy., Feuerborn R; Central Laboratory Facility, University Hospital Münster, Münster, Germany., Fischer J; Institute of Molecular Tumor Biology, University of Münster, Münster, Germany., Arndt L; Institute for Laboratory Medicine, Clinical Chemistry and Molecular Diagnos, University of Leipzig, Leipzig, Germany., Varga G; Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Münster, Germany., Pardali E; Department of Cardiology, University Hospital Münster, Münster, Germany., Seidl MD; Institute of Pharmacology and Toxicology, University of Münster, Münster, Germany., Fobker M; Central Laboratory Facility, University Hospital Münster, Münster, Germany., Liebisch G; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany., Hesse B; Department of Medicine D, Division of General Internal Medicine, Nephrology, University Hospital Münster, Münster, Germany., Lukasz AH; Department of Medicine D, Division of General Internal Medicine, Nephrology, University Hospital Münster, Münster, Germany., Rossaint J; Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Kehrel BE; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Rosenbauer F; Institute of Molecular Tumor Biology, University of Münster, Münster, Germany., Renné T; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Christoffersen C; Department of Clinical Biochemistry, Rigshospitalet, and Department of Biom, University of Copenhagen, Copenhagen, Denmark., Simoni M; Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Scien, University of Modena and Reggio Emilia, Modena, Italy., Burkhardt R; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany., Nofer JR; Central Laboratory Facility, University of Münster, Münster, Germany.

Publikováno v: JCI insight [JCI Insight] 2024 Nov 12. Date of Electronic Publication: 2024 Nov 12.

Natto consumption suppresses atherosclerotic plaque progression in LDL receptor-deficient mice transplanted with iRFP-expressing hematopoietic cells

Autor: Takeshi Kawamata, Arata Wakimoto, Takanobu Nishikawa, Masaya Ikezawa, Michito Hamada, Yuri Inoue, Kaushalya Kulathunga, Filiani Natalia Salim, Maho Kanai, Teppei Nishino, Kyle Gentleman, Chang Liu, Bryan J. Mathis, Nozomu Obana, Shinji Fukuda, Satoru Takahashi, Yuki Taya, Satoshi Sakai, Yuji Hiramatsu

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Abstract Natto, known for its high vitamin K content, has been demonstrated to suppress atherosclerosis in large-scale clinical trials through a yet-unknown mechanism. In this study, we used a previously reported mouse model, transplanting the bone m

Externí odkaz: https://doaj.org/article/5cbb993c5bf84659bf857e0120cff215

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Sex-Specific Effects of the Nlrp3 Inflammasome on Atherogenesis in LDL Receptor-Deficient Mice

Autor: Chen, Shuang, Markman, Janet L., Shimada, Kenichi, Crother, Timothy R., Lane, Malcolm, Abolhesn, Amanda, Shah, Prediman K., Arditi, Moshe

Publikováno v: In JACC: Basic to Translational Science June 2020 5(6):582-598

Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R^-/^-) Mice.

Autor: Li, Wanjing¹ (AUTHOR), Zhang, Hujin² (AUTHOR), Zhang, Lei¹ (AUTHOR), Zhang, Taipeng³ (AUTHOR), Ding, Hui¹ (AUTHOR)

Publikováno v: BioMed Research International. 7/6/2022, p1-12. 12p.