Zobrazeno 1 - 10
of 30
pro vyhledávání: '"LD50, lethal dose"'
Autor:
Mohammad Hossein Nazem Shirazi, Hosein Nourani, Amir Afkhami Goli, Nasrin Ramezani, Asieh Karimani, Amir Moghaddam Jafari
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 1280-1288 (2021)
Toxicology Reports, Vol 8, Iss, Pp 1280-1288 (2021)
Graphical abstract
Highlights • Diazinon perturbs CNS function via multiple mechanisms. • Oxidative stress is one of the main causes of diazinon-induced neurodegeneration. • Gene expression may be affected by diazinon exposure. • Diazino
Highlights • Diazinon perturbs CNS function via multiple mechanisms. • Oxidative stress is one of the main causes of diazinon-induced neurodegeneration. • Gene expression may be affected by diazinon exposure. • Diazino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5f8f7a99d29c62d9c0c016a1930aaf
http://europepmc.org/articles/PMC8261896
http://europepmc.org/articles/PMC8261896
Autor:
Raj Vuppalanchi, Mary F. Paine, Robin J. Marles, Steven J. Casper, Leonard B. Seeff, Bill J. Gurley, Hellen A. Oketch-Rabah, Tieraona Low Dog, Amy L. Roe, Jawad Ahmad, Scott A. Jordan, Gabriel I. Giancaspro, Andrew Stolz, Cynthia V. Rider, Christopher Koh, Richard Ko, Averell H. Sherker, Kan He, Jose Serrano, Robert J. Fontana, Herbert L. Bonkovsky, Víctor M. Navarro, Joseph M. Betz, Theertham P. Rao, Simona Rossi, Mahendra P. Kapoor
Publikováno v:
Toxicology Reports, Vol 7, Iss, Pp 386-402 (2020)
Toxicology Reports
Toxicology Reports
As part of the United States Pharmacopeia’s ongoing review of dietary supplement safety data, a new comprehensive systematic review on green tea extracts (GTE) has been completed. GTEs may contain hepatotoxic solvent residues, pesticide residues, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0d82c68321543dfc2fccf506f4b9cc
http://www.sciencedirect.com/science/article/pii/S2214750019306596
http://www.sciencedirect.com/science/article/pii/S2214750019306596
Autor:
Stephanie V. Kaszuba, Hui Ye
Publikováno v:
IBRO Reports, Vol 7, Iss, Pp 26-33 (2019)
IBRO Reports
IBRO Reports
Highlights • Electrode-generated currents exhibit several limitations when used to suppress seizure in clinical practice. • Magnetic stimulation provides enhanced biocompatibility, efficiency, and consistency over implanted electrode. • Clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff76e5c48cc4d86a016260b9128c4ca
http://www.sciencedirect.com/science/article/pii/S2451830119300524
http://www.sciencedirect.com/science/article/pii/S2451830119300524
Publikováno v:
Journal of Traditional and Complementary Medicine
Journal of Traditional and Complementary Medicine, Vol 11, Iss 2, Pp 82-89 (2021)
Journal of Traditional and Complementary Medicine, Vol 11, Iss 2, Pp 82-89 (2021)
Background and aim Decoctions and infusions from the aerial parts of Portulaca oleracea Linn., especially the leaves and stems, are used by traditional medicine practitioners in Nigeria to enhance fertility in humans. The scarcity of literature on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d3805bfecc6fea2882291cb69fd022
http://europepmc.org/articles/PMC7936097
http://europepmc.org/articles/PMC7936097
Autor:
Charles Oluwaseun Adetunji, Folasade M. Adeyemi, Alfredo Juárez-Saldivar, Gildardo Rivera, Olatomide A. Fadare, J.M. Agbedahunsi, Omotayo O. Oyedara
Publikováno v:
Phytomedicine Plus
Phytomedicine Plus, Vol 1, Iss 4, Pp 100135-(2021)
Phytomedicine Plus, Vol 1, Iss 4, Pp 100135-(2021)
Background SARS-CoV-2 infection or COVID-19 is a major global public health issue that requires urgent attention in terms of drug development. Transmembrane Protease Serine 2 (TMPRSS2) is a good drug target against SARS-CoV-2 because of the role it p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db5ca092376d21bfcb8f593c09fd427
https://pubmed.ncbi.nlm.nih.gov/35403085
https://pubmed.ncbi.nlm.nih.gov/35403085
Publikováno v:
Pharmacological Research
Graphical abstract Molecular targets modulated by artemisinins in respiratory diseases.
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184b9b3d7b7767e97cb84ac3227c7da4
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 5, Iss, Pp 108-112 (2018)
Toxicology Reports, Vol 5, Iss, Pp 108-112 (2018)
Graphical abstract Schematic representation of compounds isolated from Ajuga bracteosa and their antimutagenic activity.
Highlights • Four compounds 1) 14, 15-dihydroajugapitin and 2) 8-o-acetylharpagide were isolated from Ajuga bracteosa. •
Highlights • Four compounds 1) 14, 15-dihydroajugapitin and 2) 8-o-acetylharpagide were isolated from Ajuga bracteosa. •
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8943a21f06419121d08b0ca7cc109592
http://europepmc.org/articles/PMC5977163
http://europepmc.org/articles/PMC5977163
Publikováno v:
Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 282-286 (2017)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
The C. elegans NB327 mutant strain is characterized for the knockdown of the dic-1 gene. The dic-1 gene is homologous to the dice-1 gene in humans, encoding the protein DICE-1 as a tumor suppressor. Absence or under-regulation of the dice-1 gene can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722361e1f073a00ae751901b21c179c7
http://www.sciencedirect.com/science/article/pii/S2405580816302710
http://www.sciencedirect.com/science/article/pii/S2405580816302710
Publikováno v:
Toxicology Reports
Graphical abstract
Highlights • In the present paper, the histopathological changes of liver and kidney tissues associated with Vipera russelli envenomation and systemic venom neutralization potential of aqueous Alstonia scholaris Linn bark ex
Highlights • In the present paper, the histopathological changes of liver and kidney tissues associated with Vipera russelli envenomation and systemic venom neutralization potential of aqueous Alstonia scholaris Linn bark ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa8d68ff6ee245dc451682d907aa0c09
https://pubmed.ncbi.nlm.nih.gov/30319940
https://pubmed.ncbi.nlm.nih.gov/30319940
Autor:
Aparamita Pandey, Medhamurthy Rudraiah
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 2, Iss C, Pp 1075-1085 (2015)
Toxicology Reports, Vol 2, Iss C, Pp 1075-1085 (2015)
The effect of Roundup® on adrenal gland steroidogenesis and signaling pathway associated with steroid production was investigated. Doses of 10, 50, 100 and 250mg/kg bw/d Roundup® were administered for two weeks to adult male rats. The 10mg/kg bw/d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dff91e1f01212dc80ac3f1a472c9637