Výsledky vyhledávání

Mortality hazard functions as related to neutropenia at different times after marrow transplantation

Autor: Fritz Offner, Paul J. Martin, Beverly Torok-Storb, Gary Schoch, LD Fisher

Publikováno v: Blood. 88:4058-4062

We characterized the relationship between severe neutropenia and risk of death in 2,276 patients after marrow transplantation to define objective and clinically relevant criteria that could be used to judge the timing and potential value of intervent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a97dc48a9593f3af194a042acd07fdc
https://doi.org/10.1182/blood.v88.10.4058.bloodjournal88104058

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Fungal Liver Infection in Marrow Transplant Recipients: Prevalence at Autopsy, Predisposing Factors, and Clinical Features

Autor: Joel D. Meyers, LD Fisher, George B. McDonald, W. G. Meyer, David Myerson, Raleigh A. Bowden, Howard M. Shulman, George E. Sale, H. G. Schoch, Robert C. Hackman, F. Rossetti, D. L. Brawner

Publikováno v: Clinical Infectious Diseases. 20:801-811

To determine the prevalence of fungal liver infection at autopsy in marrow transplant recipients, we reviewed autopsy results for the period 1980-1989. Cases were compared to randomly chosen autopsied controls without fungal infection. Fungal liver i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5769b95ae4c9bc8e85698f5b25d63b43
https://doi.org/10.1093/clinids/20.4.801

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Simulation as a design tool for phase I/II clinical trials: An example from bone marrow transplantation

Autor: Paul J. Martin, Ted Gooley, Mary Pettinger, LD Fisher

Publikováno v: Controlled Clinical Trials. 15:450-462

We discuss the design and analysis of a proposed phase I/II clinical trial in bone marrow transplantation whereby dose modifications that decrease the risk of one complication increase the risk of another. Trials of this type are carried out to deter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2ebc5710667bc20997c4fd48fb5e11
https://doi.org/10.1016/0197-2456(94)90003-5

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Marrow transplantation for chronic myeloid leukemia: a randomized study comparing cyclophosphamide and total body irradiation with busulfan and cyclophosphamide

Autor: William I. Bensinger, John A. Hansen, Kristine Doney, Buckner Cd, Eileen Bryant, Raleigh A. Bowden, LD Fisher, H. J. Deeg, Thomas Ed, Reginald A. Clift

Publikováno v: Blood. 84:2036-2043

A prospective randomized study was conducted comparing two conditioning regimens for the treatment of patients with chronic myeloid leukemia in chronic phase by marrow transplantation from HLA identical siblings. Sixty-nine patients received 60 mg/kg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fca4a26dfdd103260f47b76874ce46d4
https://doi.org/10.1182/blood.v84.6.2036.2036

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Retrovirus-mediated gene transduction into long-term repopulating marrow cells of dogs

Autor: K Kawahara, R To, LD Fisher, K Mullally, A D Miller, FR Appelbaum, D Stewart, Theodore C. Graham, S Goehle, Friedrich Schuening

Publikováno v: Blood. 78:2568-2576

Amphotropic helper-free retrovirus vectors containing the bacterial neomycin phosphotransferase gene (neo) and the human adenosine deaminase gene (adenosine aminohydrolase, EC 3.5.4.4; ADA) were used to transduce canine marrow cells. In one approach,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2d45389f9ecd6398943992578f2f90
https://doi.org/10.1182/blood.v78.10.2568.bloodjournal78102568

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A retrospective analysis of therapy for acute graft-versus-host disease: secondary treatment

Autor: John A. Hansen, Gary Schoch, Frederick R. Appelbaum, Paul J. Martin, George B. McDonald, Rainer Storb, LD Fisher, Vera Byers

Publikováno v: Blood. 77:1821-1828

We have reviewed results of secondary therapy in 427 patients with acute graft-versus-host disease (GVHD) who did not have a durable satisfactory response after primary treatment. At the beginning of secondary treatment, 320 patients (75%) had rash,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bcc2b7747623bc962e840e571150bda
https://doi.org/10.1182/blood.v77.8.1821.1821

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Use of a Probe to Repeat Sequence of the Y Chromosome for Detection of Host Cells in Peripheral Blood of Bone Marrow Transplant Recipients

Autor: D M Durnam, Donna Przepiorka, Thomas Ed, LD Fisher

Publikováno v: American Journal of Clinical Pathology. 95:201-206

In situ hybridization for the Y chromosome (Y-ISH) was used to identify residual host cells in the peripheral blood of 51 recipients of sex-mismatched allogeneic marrow not depleted of T cells following conditioning with high-dose cyclophosphamide an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5f0bb8f9e6cecfd089f3566f60d15c
https://doi.org/10.1093/ajcp/95.2.201

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Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens [see comments]

Autor: FR Appelbaum, Patrick G. Beatty, LD Fisher, Kristine Doney, Buckner Cd, Finn Bo Petersen, Claudio Anasetti, Scott I. Bearman, William I. Bensinger, Reginald A. Clift

Publikováno v: Blood. 76:1867-1871

A randomized trial of 12.0 Gy versus 15.75 Gy of total body irradiation (TBI) was performed in patients with acute myeloid leukemia undergoing allogeneic marrow transplantation while in first complete remission. All patients received 120 mg/kg cyclop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd2be68d14a187bee5ab649c8feb0a8
https://doi.org/10.1182/blood.v76.9.1867.bloodjournal7691867

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Value of day 100 screening studies for predicting the development of chronic graft-versus-host disease after allogeneic bone marrow transplantation

Autor: Keith M. Sullivan, Jean E. Sanders, Mark M. Schubert, George E. Sale, LD Fisher, C. Beckham, Thomas H. Morton, TP Jr Loughran, Howard M. Shulman, Robert P. Witherspoon

Publikováno v: Blood. 76:228-234

We prospectively evaluated 169 patients with a number of screening studies performed between 71 to 121 days after allogeneic marrow transplantation to detect the development of chronic graft-versus-host disease (GVHD). Group 1 patients (n = 78) were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60acb8bb9b7272f3c1c7f6d177fd772c
https://doi.org/10.1182/blood.v76.1.228.228

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Cytomegalovirus infection after autologous bone marrow transplantation: occurrence of cytomegalovirus disease and effect on engraftment

Autor: Thomas Ed, P. Reusser, Buckner Cd, LD Fisher, Joel D. Meyers

Publikováno v: Blood. 75:1888-1894

Epidemiologic and clinical characteristics of cytomegalovirus (CMV) infection and disease were analyzed retrospectively in 159 autologous marrow transplant recipients. The probability of CMV infection by day 100 after transplant was 22.5% in patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a40e2f48e0a39a6512023ceecc074a
https://doi.org/10.1182/blood.v75.9.1888.1888

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