Zobrazeno 1 - 10
of 993
pro vyhledávání: '"LC3B"'
Autor:
Bin Tian, Yanming Tian, Xuetong Wang, Dongjie Cai, Liping Wu, Mingshu Wang, Renyong Jia, Shun Chen, Dekang Zhu, Mafeng Liu, Qiao Yang, Ying Wu, Xinxin Zhao, Shaqiu Zhang, Di Sun, Juan Huang, Xumin Ou, Zhen Wu, Anchun Cheng
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-15 (2024)
Abstract Migratory birds are important vectors for virus transmission, how migratory birds recognize viruses and viruses are sustained in birds is still enigmatic. As an animal model for waterfowl among migratory birds, studying and dissecting the an
Externí odkaz:
https://doaj.org/article/cb341ab00cd2424298a739c84b4bf1ac
Autor:
Aysam M. Fayed, M.A. Abdelzaher, Neamah Hassoni Mahdi, Dina M.R. AlKhafaf, Mohamed AbdElRahman, Ahmed Khalid Aldhalmi, Zahraa Haleem Al-Qaim, Rania Abd Elmohsen Abo El nour, Heba G. Abdelzaher, Alaa Muqbil Alsirhani, Salwa El. Saied Morsi
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 22, Iss 3, Pp 100395- (2024)
Prostate cancer (PCa) is a prevalent form of malignancy in males and is a significant contributor to cancer-related mortality worldwide. Because of this, studying the molecular processes of PCa cell growth and death is crucial. Hence, it is imperativ
Externí odkaz:
https://doaj.org/article/5965fddd5be64699a310f3da361c5518
Autor:
K. V. Nikulnikov, V. A. Bogdanova, L. V. Spirina, S. Yu. Chizhevskaya, I. V. Kondakova, E. L. Choynzonov, V. I. Chernov
Publikováno v:
Успехи молекулярной онкологии, Vol 11, Iss 1, Pp 46-54 (2024)
Introduction. Melanoma is the most dangerous neoplasm of the skin, characterized by a malignant and aggressive course. Transcriptional and growth factors, components of the AKT/mTOR signaling pathway, receptors and ligands of programmed cell death ar
Externí odkaz:
https://doaj.org/article/6b95f20c2dfc4abd81e7719a76815f51
Autor:
Xiaohui Hua, Daimin Xiang, Jiheng Xu, Shouyue Zhang, Shuai Wu, Zhongxian Tian, Junlan Zhu, Chuanshu Huang
Publikováno v:
Translational Oncology, Vol 51, Iss , Pp 102178- (2025)
Isorhapontigenin (ISO), an active compound isolated from the Chinese herb Gnetum Cleistostachyum, exhibited strong preventive and therapeutic effects on bladder cancer (BC) both in vitro and in vivo. Our previous studies revealed that ISO-induced aut
Externí odkaz:
https://doaj.org/article/a3d43bd726ba47678b8a1f6ddd91bd90
Autor:
Isaac Tamargo-Gómez, Manuel Fernández-Sanjurjo, Helena Codina-Martínez, Cristina Tomás-Zapico, Eduardo Iglesias-Gutiérrez, Benjamín Fernández-García, Álvaro F. Fernández
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 10, p 348 (2024)
Background: Autophagy is a conserved catabolic process that promotes cellular homeostasis and health. Although exercise is a well-established inducer of this pathway, little is known about the effects of different types of training protocols on the a
Externí odkaz:
https://doaj.org/article/5c3cc669ace34d33b4f18fef2d5b1464
Autor:
Ivan Brdar, Anita Racetin, Ivo Jeličić, Katarina Vukojević, Ljiljana Vučković, Dragan Ljutić, Mirna Saraga-Babić, Natalija Filipović
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9152 (2024)
Autophagy is the primary intracellular degradation system, and it plays an important role in many biological and pathological processes. Studies of autophagy involvement in developmental processes are important for understanding various processes. Am
Externí odkaz:
https://doaj.org/article/c761fc7138e047c5974f3a00c82639ee
Autor:
Mirko Maglica, Nela Kelam, Ilija Perutina, Anita Racetin, Azer Rizikalo, Natalija Filipović, Ivana Kuzmić Prusac, Josip Mišković, Katarina Vukojević
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6829 (2024)
The purpose of this study was to evaluate the spatiotemporal immunoexpression pattern of microtubule-associated protein 1 light chain 3 beta (LC3B), glucose-regulated protein 78 (GRP78), heat shock protein 70 (HSP70), and lysosomal-associated membran
Externí odkaz:
https://doaj.org/article/3bd51269325e4f0fa0376f7b2730564c
Autor:
Yuko Shirono, Vladimir Bilim, Tsutomu Anraku, Hiroo Kuroki, Akira Kazama, Masaki Murata, Kaede Hiruma, Yoshihiko Tomita
Publikováno v:
Current Oncology, Vol 30, Iss 6, Pp 5350-5365 (2023)
Advanced bladder cancer (BC) (local invasive and/or metastatic) is not curable even with cytotoxic chemotherapy, immune checkpoint inhibitors, and targeted treatment. Targeting GSK-3β is a promising novel approach in advanced BC. The induction of au
Externí odkaz:
https://doaj.org/article/928668710b4b4b77a11f83773094fb54
Autor:
Marco Albani, Enrico Mario Alessandro Fassi, Roberta Manuela Moretti, Mariangela Garofalo, Marina Montagnani Marelli, Gabriella Roda, Jacopo Sgrignani, Andrea Cavalli, Giovanni Grazioso
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4622 (2024)
(1) Autophagy plays a significant role in development and cell proliferation. This process is mainly accomplished by the LC3 protein, which, after maturation, builds the nascent autophagosomes. The inhibition of LC3 maturation results in the interfer
Externí odkaz:
https://doaj.org/article/58732233297a4e25b1dad2b9454abd9b
Autor:
Cédric Garcia, Baptiste Compagnon, Agnès Ribes, Sophie Voisin, Fanny Vardon-Bounes, Bernard Payrastre
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn November 2021, the SARS-CoV-2 Omicron variant of concern has emerged and is currently dominating the COVID-19 pandemic over the world. Omicron displays a number of mutations, particularly in the spike protein, leading to specific chara
Externí odkaz:
https://doaj.org/article/a0b1b7e716284a9faa601e982ef3efc2