Zobrazeno 1 - 10
of 582
pro vyhledávání: '"LC3-associated phagocytosis"'
Autor:
Laura Seldeslachts, Frederik Staels, Marina Gkountzinopoulou, Cato Jacobs, Birger Tielemans, Eliane Vanhoffelen, Agustin Reséndiz-Sharpe, Lander De Herdt, Jeason Haughton, Teresa Prezzemolo, Oliver Burton, Simon Feys, Frank L. van de Veerdonk, Agostinho Carvalho, Lieve Naesens, Patrick Matthys, Katrien Lagrou, Erik Verbeken, Georgios Chamilos, Joost Wauters, Stephanie Humblet-Baron, Greetje Vande Velde
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105347- (2024)
Summary: Background: Influenza-associated pulmonary aspergillosis (IAPA) is a severe fungal superinfection in critically ill influenza patients that is of incompletely understood pathogenesis. Despite the use of contemporary therapies with antifungal
Externí odkaz:
https://doaj.org/article/f1c0a658976b449e99040d50fd414abc
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveIn the defense against microorganisms like Candida albicans, macrophages recruit LC3(Microtubule-associated protein 1A/1B-light chain 3) to the periplasm, engaging in the elimination process through the formation of a single-membrane phagoso
Externí odkaz:
https://doaj.org/article/c855046bd8894b10b115612ee474d8a1
Autor:
Xiang-Xin Chen, Tao Tao, Xun-Zhi Liu, Wei Wu, Jin-Wei Wang, Ting-Ting Yue, Xiao-Jian Li, Yan Zhou, Sen Gao, Bin Sheng, Zheng Peng, Hua-Jie Xu, Peng-Fei Ding, Ling-Yun Wu, Ding-Ding Zhang, Yue Lu, Chun-Hua Hang, Wei Li
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background The phagocytosis and homeostasis of microglia play an important role in promoting blood clearance and improving prognosis after subarachnoid hemorrhage (SAH). LC3-assocaited phagocytosis (LAP) contributes to the microglial phagocy
Externí odkaz:
https://doaj.org/article/42993ade0bfa4573bdf4410daa1e121d
Autor:
Samrah Masud, Jiajun Xie, Bart J.M. Grijmans, Sander van der Kooij, Rui Zhang, Tomasz K. Prajsnar, Annemarie H. Meijer
Publikováno v:
Autophagy Reports, Vol 2, Iss 1 (2023)
DRAM1 is an infection inducible autophagy modulator, previously shown to promote autophagic and lysosomal defense responses against the intracellular pathogen Mycobacterium marinum. However, its possible role in other anti-bacterial autophagic mechan
Externí odkaz:
https://doaj.org/article/b5e9550099de47c6a55374bec8032b0b
Publikováno v:
Медицинская иммунология, Vol 25, Iss 2, Pp 233-252 (2023)
Previously, autophagy was termed as a mechanism used by the cells with a lack of essential nutrients supporting homeostasis. Over the decade of studies, autophagy proved to be a more complex, ambiguous mechanism. Its activation depends on the nature
Externí odkaz:
https://doaj.org/article/6ebc15f299624ae9a19d5922ea42cbb0
Akademický článek
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Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 25-28 (2022)
The process of LC3-associated phagocytosis (LAP) combines elements of phagocytosis and autophagy. LAP is involved in clearance of pathogens and cell debris, antigen presentation, and immune signaling. However, the mechanistic role of LAP is incomplet
Externí odkaz:
https://doaj.org/article/6fff0ad2ce764bdf9af1541af47baaff
Akademický článek
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Autor:
Sarit Cohen-Kedar, Efrat Shaham Barda, Keren Masha Rabinowitz, Danielle Keizer, Hanan Abu-Taha, Shoshana Schwartz, Kawsar Kaboub, Liran Baram, Eran Sadot, Ian White, Nir Wasserberg, Meirav Wolff-Bar, Adva Levy-Barda, Iris Dotan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundIntestinal epithelial cells (IECs) are the first to encounter luminal microorganisms and actively participate in intestinal immunity. We reported that IECs express the β-glucan receptor Dectin-1, and respond to commensal fungi and β-gluca
Externí odkaz:
https://doaj.org/article/a633c5860ae44b019e1bafed518042e9