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pro vyhledávání: '"LC–MS/MS, liquid chromatography tandem mass spectrometry"'
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Autor:
Andreas Zollner, Nicole Przysiecki, Sophie Macheiner, Vera Reinstadler, Barbara Jelusic, Simon J. Reider, Herbert Tilg, Christina Watschinger, Alexandra Pfister, Herbert Oberacher, Alexander R. Moschen, Bernhard Texler
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 383-404 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Objective By interfering with multiple cytokines, human Janus kinase inhibitors (JAKis) are of growing importance in the treatment of malignant and inflammatory conditions. Although tofacitinib has demonstrated efficacy as the first-in-class JAKi in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6e0dffe3ffcc5c8d849bd534a91dfc
http://www.sciencedirect.com/science/article/pii/S2352345X21001922
http://www.sciencedirect.com/science/article/pii/S2352345X21001922
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 23, Iss, Pp 44-49 (2022)
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab
Highlights • Mass spectrometry produces data which can be used to monitor instrument performance. • We describe a tool that parses and visualizes mass spectrometry data. • This toolkit can be applied to increase quality control for a complex LC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3da7bc2257c15592067041befb1804
https://doi.org/10.1016/j.jmsacl.2021.12.003
https://doi.org/10.1016/j.jmsacl.2021.12.003
Publikováno v:
Current Research in Food Science
Current Research in Food Science, Vol 5, Iss, Pp 182-190 (2022)
Current Research in Food Science, Vol 5, Iss, Pp 182-190 (2022)
Post-translational modification structure of food's proteins might be changed during processing, thereby affecting the nutritional characteristics of the food product. In this study, differences in protein N-glycosylation patterns between milk and yo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b32975f3c5eef2a006155bfcb400632
http://europepmc.org/articles/PMC8763629
http://europepmc.org/articles/PMC8763629
Autor:
Matthew James Carlo, Amanda Patrick
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 23, Iss, Pp 14-25 (2022)
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab
Graphical abstract
Infrared multiple photon dissociation (IRMPD) spectroscopy is a powerful tool used to probe the vibrational modes–and, by extension, the structure—of an ion within an ion trap mass spectrometer. Compared to traditional FTI
Infrared multiple photon dissociation (IRMPD) spectroscopy is a powerful tool used to probe the vibrational modes–and, by extension, the structure—of an ion within an ion trap mass spectrometer. Compared to traditional FTI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1896b9cca9d995eb7964b767cf209078
http://www.sciencedirect.com/science/article/pii/S2667145X2100033X
http://www.sciencedirect.com/science/article/pii/S2667145X2100033X
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 21, Iss, Pp 19-26 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab
Graphical abstract
Highlights • 3-methoxytyramine (3MT) aids diagnosis of dopamine-producing tumors and metastases. • A sensitive and specific LC-MS/MS method was developed to measure 3MT in plasma. • 3MT was elevated in 46% of samples wit
Highlights • 3-methoxytyramine (3MT) aids diagnosis of dopamine-producing tumors and metastases. • A sensitive and specific LC-MS/MS method was developed to measure 3MT in plasma. • 3MT was elevated in 46% of samples wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08c4943e1a4fd040c375868b3c78615
http://www.sciencedirect.com/science/article/pii/S2667145X21000134
http://www.sciencedirect.com/science/article/pii/S2667145X21000134
Autor:
Shengtao Yuan, Han Luwei, Dezhen Peng, Zhiqiang Wang, Hongzhi Du, Li Sun, Zhang Xian, Zhao Liwen, Danyu Du, Ligong Lu, Meixiao Zhan, Zhibo Zhang, Yong Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1526-1540 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Acute myeloid leukaemia (AML) is the most common form of acute leukaemia in adults, with increasing incidence with age and a generally poor prognosis. Almost 20% of AML patients express mutant isocitrate dehydrogenase 2 (mIDH2), which leads to the ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1989ebe7a9db18d2c8b52de1673685c1
http://www.sciencedirect.com/science/article/pii/S2211383521000769
http://www.sciencedirect.com/science/article/pii/S2211383521000769
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2486-2496 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2486-2496 (2021)
Graphical abstract
Highlights • N-glycoproteome of H. contortus discloses 291 proteins harboring 425 modification sites. • Glycoconjugates occur predominantly in the intestine and gonads of the adult parasitic worms. • Selected proteins of
Highlights • N-glycoproteome of H. contortus discloses 291 proteins harboring 425 modification sites. • Glycoconjugates occur predominantly in the intestine and gonads of the adult parasitic worms. • Selected proteins of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1048244b39688b28ad351e2dbd8c94
http://europepmc.org/articles/PMC8113779
http://europepmc.org/articles/PMC8113779
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 19, Iss, Pp 34-45 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 19, Iss, Pp 34-45 (2021)
Background Nitric oxide (NO) plays an important role in endothelial homeostasis. Asymmetric dimethyl arginine (ADMA), L-N monomethyl arginine (L-NMMA) and symmetric dimethyl arginine (SDMA), which are derivatives of methylarginine, directly or indire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2055d3fbb4930fa6ebe6940f0dd56ef
http://europepmc.org/articles/PMC8601011
http://europepmc.org/articles/PMC8601011
Autor:
Carmela D. Tan, Andrej Gabrovsek, E. Rene Rodriguez, Claudiu V. Cotta, Mazen Hanna, Lidiya Sul, Joseph P. Donnelly
Publikováno v:
JACC: CardioOncology
JACC. CardioOncology, Vol 2, Iss 1, Pp 127-130 (2020)
JACC. CardioOncology, Vol 2, Iss 1, Pp 127-130 (2020)
Two distinct types of systemic amyloidosis, light chain (AL) and transthyretin (ATTR), account for >95% of diagnosed cardiac amyloidosis (CA) ([1][1]). AL arises from a clonal population of plasma cells that produce misfolded immunoglobulin light cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b58d9f720d06d50486faa5bc72d4ea
https://doi.org/10.1016/j.jaccao.2020.01.001
https://doi.org/10.1016/j.jaccao.2020.01.001