Zobrazeno 1 - 10
of 23
pro vyhledávání: '"LAWTON, Geoffrey"'
Autor:
D. Bradshaw, Elliott Lh, Davis Peter David, T. A. Griffiths, John S. Nixon, Hill Christopher Huw, S. E. Wilkinson, Lawton Geoffrey, J. Wadsworth, D. Westmacott, A. D. Sedgwick, M. J. Mulqueen, H. Kumar
Publikováno v:
Agents and Actions. 37:85-89
The protein kinase C family of enzymes is thought to be important in mediating signal transduction. Ro 31-8830 is a novel, potent inhibitor of protein kinase C, derived from the non-selective protein kinase inhibitor staurosporine. In this paper we d
Autor:
A. D’Arcy, John S. Nixon, D. Bradshaw, E. J. Murray, Neera Borkakoti, Hill Christopher Huw, David Williams, F. K. Winkler, Paul Anthony Brown, Michael J. Broadhurst, Lawton Geoffrey, K. M. K. Bottomley, William Henry Johnson, E. J. Lewis
Publikováno v:
Structure-Based Drug Design ISBN: 9789048150786
Collagenase belongs to a family of zinc and calcium dependent enzymes, the matrix metalloproteinases (MMPs), which are synthesised as zymogens in connective tissue (1, 2). The MMPs, also called matrixins, represent viable targets for drug design sinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c4e716336a981a0f2f6e815c2654a04
https://doi.org/10.1007/978-94-015-9028-0_7
https://doi.org/10.1007/978-94-015-9028-0_7
Autor:
Breda M. Twomey, Davis Peter David, John S. Nixon, Hill Christopher Huw, Lawton Geoffrey, Lucy H. Elliott, Hari Kumar, M.Maureen Dale, R.E. Muid, J. Wadsworth, S. E. Wilkinson
Publikováno v:
FEBS letters. 293(1-2)
A novel, bis-indolylmaleimide, Ro 31-8425, bearing a conformationally restricted side chain, inhibits protein kinase C isolated from rat brain and human neutrophils with a high degree of selectivity over cAMP-dependent kinase and Ca2−/calmodulin-de
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1 (0300922X); 1987, p877-884, 8p
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1 (0300922X); 1987, p885-897, 13p
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1 (0300922X); 1987, p899-902, 4p
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1 (0300922X); 1986, p1011-1019, 9p
Autor:
Muid, Robert E., Dale, M.Maureen, Davis, Peter D., Elliott, Lucy H., Hill, Christopher H., Kumar, Hari, Lawton, Geoffrey, Twomey, Breda M., Wadsworth, Julie, Wilkinson, Sandra E., Nixon, John S.
Publikováno v:
FEBS Letters; January 1991, Vol. 293 Issue: 1 p169-172, 4p
Autor:
Attwood, Michael R., Francis, R.John, Hassall, Cedric H., Kröhn, Antonin, Lawton, Geoffrey, Natoff, Ian L., Nixon, John S., Redshaw, Sally, Thomas, W.Anthony
Publikováno v:
FEBS Letters; January 1984, Vol. 165 Issue: 2 p201-206, 6p
Autor:
BOTTOMLEY, Kevin M., BORKAKOTI, Neera, BRADSHAW, David, BROWN, Paul A., BROADHURST, Michael J., BUDD, John M., ELLIOTT, Lucy, EYERS, Pat, HALLAM, Trevor J., HANDA, Balraj K., HILL, Christopher H., JAMES, Maisie, LAHM, Hans-Werner, LAWTON, Geoffrey, MERRITT, Janet E., NIXON, John S., RÖTHLISBERGER, Urs, WHITTLE, Amanda, JOHNSON, William H.
Publikováno v:
Biochemical Journal; April 1997, Vol. 323 Issue: 2 p483-488, 6p