THE HUMAN KERATINOCYTE 2-DIMENSIONAL PROTEIN DATABASE (UPDATE-1994) - TOWARDS AN INTEGRATED APPROACH TO THE STUDY OF CELL-PROLIFERATION, DIFFERENTIATION AND SKIN-DISEASES

Autor: LEFFERS, H, DEJGAARD, K, GROMOV, P, VORUM, H, VASSILEV, A, LIU, XD, CELIS, A, BASSE, B, LAURIDSEN, JB, RATZ, GP, ANDERSEN, AH, WALBUM, E, KJAERGAARD, I, ANDERSEN, I, PUYPE, M, VANDAMME, J, VANDEKERCKHOVE, J, BASKIN, YASEMİN, MADSEN, P, HONORE, B, CELIS, JE, OLSEN, E, RASMUSSEN, HH

The master two-dimensional (2-D) gel database of human keratinocytes currently lists 3087 cellular proteins (2168 isoelectric focusing, IEF; and 919 nonequilibrium pH gradient electrophoresis, NEPHGE), many of which correspond to posttranslational mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2605::109f2a7a1fece945c2ad81a7fa199004
https://avesis.deu.edu.tr/publication/details/e7d9c446-392d-4302-b4c8-3ba6a62a97a6/oai

Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: a study in male mice.

Autor: Didriksen M; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Fejgin K; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Nilsson SR; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Birknow MR; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Grayton HM; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Larsen PH; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Lauridsen JB; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Nielsen V; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Celada P; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Santana N; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Kallunki P; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Christensen KV; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Werge TM; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Stensbøl TB; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Egebjerg J; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Gastambide F; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Artigas F; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Bastlund JF; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge)., Nielsen J; From H. Lundbeck A/S, Research DK, Valby, Denmark (Didriksen Fejgin, Birknow, Larsen, Lauridsen, Nielsen, Kallunki, Christensen, Stensbøl, Egebjerg, Nielsen); the Department of Psychology, University of Cambridge, Cambridge, UK (Nilsson); the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK (Nilsson); the Lilly Centre for Cognitive Neuroscience, Lilly Research Laboratories, Windlesham, UK (Grayton, Gastambide); the Institut d'Investigacions Biomèdiques de Barcelona, Barcelona, Spain (Celada, Artigas); the Centro de Investigación Biomédica en Red de Salud Mental, Spain (Santana, Artigas); the Institute of Biological Psychiatry, MHC Sct. Hans, Copenhagen Mental Health Services; and the Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen; iPSYCH - The Lundbeck Foundation's Initiative for Integrative Psychiatric Research, Roskilde, Denmark (Werge).

Publikováno v: Journal of psychiatry & neuroscience : JPN [J Psychiatry Neurosci] 2017 Jan; Vol. 42 (1), pp. 48-58.

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A mouse model that recapitulates cardinal features of the 15q13.3 microdeletion syndrome including schizophrenia- and epilepsy-related alterations.

Autor: Fejgin K; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark., Nielsen J; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark., Birknow MR; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark., Bastlund JF; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark., Nielsen V; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark., Lauridsen JB; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark., Stefansson H; deCODE Genetics, Reykjavik, Iceland., Steinberg S; deCODE Genetics, Reykjavik, Iceland., Sorensen HB; Department of Electrical Engineering, Technical University of Denmark, Kongens Lyngby., Mortensen TE; Department of Electrical Engineering, Technical University of Denmark, Kongens Lyngby., Larsen PH; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark., Klewe IV; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark., Rasmussen SV; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark., Stefansson K; deCODE Genetics, Reykjavik, Iceland., Werge TM; Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Copenhagen University Hospital, Roskilde, Denmark., Kallunki P; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark., Christensen KV; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark., Didriksen M; Neuroscience Research DK, H. Lundbeck A/S, Valby, Denmark. Electronic address: MDI@lundbeck.com.

Publikováno v: Biological psychiatry [Biol Psychiatry] 2014 Jul 15; Vol. 76 (2), pp. 128-37. Date of Electronic Publication: 2013 Oct 03.