Zobrazeno 1 - 10
of 106
pro vyhledávání: '"LAURENT GATTO"'
Autor:
Olivier G. Pollé, Sébastien Pyr dit Ruys, Julie Lemmer, Camille Hubinon, Manon Martin, Gaetan Herinckx, Laurent Gatto, Didier Vertommen, Philippe A. Lysy
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Partial remission (PR) occurs in only half of people with new-onset type 1 diabetes (T1D) and corresponds to a transient period characterized by low daily insulin needs, low glycemic fluctuations and increased endogenous insulin secretion. W
Externí odkaz:
https://doaj.org/article/037a3c78bbd347d1a334f096a3b84a6c
Autor:
Sophie Pirenne, Fátima Manzano-Núñez, Axelle Loriot, Sabine Cordi, Lieven Desmet, Selda Aydin, Catherine Hubert, Sébastien Toffoli, Nisha Limaye, Christine Sempoux, Mina Komuta, Laurent Gatto, Frédéric P. Lemaigre
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Most studies on tumour progression from precursor lesion toward gallbladder adenocarcinoma investigate lesions sampled from distinct patients, providing an overarching view of pathogenic cascades. Whether this reflects the tumouri
Externí odkaz:
https://doaj.org/article/888ee42661c44f70b730f4a7d0dccaca
Autor:
Philippe Hauchamps, Babak Bayat, Simon Delandre, Mehdi Hamrouni, Marie Toussaint, Stephane Temmerman, Dan Lin, Laurent Gatto
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-22 (2024)
Abstract Background With the increase of the dimensionality in flow cytometry data over the past years, there is a growing need to replace or complement traditional manual analysis (i.e. iterative 2D gating) with automated data analysis pipelines. A
Externí odkaz:
https://doaj.org/article/698efd71688143ae9a7b07d814f29150
Gut microbiome modulates tacrolimus pharmacokinetics through the transcriptional regulation of ABCB1
Autor:
Alexandra L. Degraeve, Vincent Haufroid, Axelle Loriot, Laurent Gatto, Vanessa Andries, Lars Vereecke, Laure Elens, Laure B. Bindels
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Background Following solid organ transplantation, tacrolimus (TAC) is an essential drug in the immunosuppressive strategy. Its use constitutes a challenge due to its narrow therapeutic index and its high inter- and intra-pharmacokinetic (PK)
Externí odkaz:
https://doaj.org/article/43607ac124fa45699da65154bbfffbf5
Autor:
Oliver M. Crook, Colin T. R. Davies, Lisa M. Breckels, Josie A. Christopher, Laurent Gatto, Paul D. W. Kirk, Kathryn S. Lilley
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Changes in protein subcellular localization can be determined using mass spectrometry. Here, the authors present a statistical approach to determine relocalising proteins from spatial proteomics experiments.
Externí odkaz:
https://doaj.org/article/2ab3daf7eb8d40e0ab4ad9e1fbd4cdd3
Autor:
Kelly B Eckenrode, Dario Righelli, Marcel Ramos, Ricard Argelaguet, Christophe Vanderaa, Ludwig Geistlinger, Aedin C Culhane, Laurent Gatto, Vincent Carey, Martin Morgan, Davide Risso, Levi Waldron
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1011324 (2023)
BackgroundThe majority of high-throughput single-cell molecular profiling methods quantify RNA expression; however, recent multimodal profiling methods add simultaneous measurement of genomic, proteomic, epigenetic, and/or spatial information on the
Externí odkaz:
https://doaj.org/article/5aceb3092f5d4538ae21806c28726846
Autor:
Manon Moulis, Steve Vincent Maurice Runser, Laura Glorieux, Nicolas Dauguet, Christophe Vanderaa, Laurent Gatto, Donatienne Tyteca, Patrick Henriet, Francesca M. Spagnoli, Dagmar Iber, Christophe E. Pierreux
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Development of the pancreas is driven by an intrinsic program coordinated with signals from other cell types in the epithelial environment. These intercellular communications have been so far challenging to study because of the low concentra
Externí odkaz:
https://doaj.org/article/3635ecf0825b4dbab51e89b71438d34e
Autor:
Joseph P. Dewulf, Manon Martin, Sandrine Marie, Fabie Oguz, Leila Belkhir, Julien De Greef, Jean Cyr Yombi, Xavier Wittebole, Pierre-François Laterre, Michel Jadoul, Laurent Gatto, Guido T. Bommer, Johann Morelle
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract SARS-CoV-2 causes major disturbances in serum metabolite levels, associated with severity of the immune response. Despite the numerous advantages of urine for biomarker discovery, the potential association between urine metabolites and disea
Externí odkaz:
https://doaj.org/article/d2faae9dc89846cf98d443222291a0d8
Autor:
Justine Dontaine, Asma Bouali, Frederic Daussin, Laurent Bultot, Didier Vertommen, Manon Martin, Raahulan Rathagirishnan, Alexanne Cuillerier, Sandrine Horman, Christophe Beauloye, Laurent Gatto, Benjamin Lauzier, Luc Bertrand, Yan Burelle
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
An in vitro assay in isolated heart mitochondria reveals that O-GlcNAcase inhibitor NButGT rapidly increases protein O-GlcNAcylation leading to increased respiratory capacity and complex I activity and decreased ROS release.
Externí odkaz:
https://doaj.org/article/82461742574a45b882dff02102e4af48
Autor:
Antoine A Harvengt, Olivier G Polle, Manon Martin, Aline van Maanen, Laurent Gatto, Philippe A Lysy
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294982 (2023)
AimsTo evaluate whether parameters of post-hypoglycemic hyperglycemia (PHH) correlated with glucose homeostasis during the first year after type 1 diabetes onset and helped to distinguish pediatric patients undergoing partial remission or not.Methods
Externí odkaz:
https://doaj.org/article/f5578409012f4d429a062e0011fde2c5