Zobrazeno 1 - 10
of 52
pro vyhledávání: '"LAURA MENOTTI"'
Autor:
Guglielmo Faggioli, Laura Menotti, Stefano Marchesin, Adriano Chió, Arianna Dagliati, Mamede de Carvalho, Marta Gromicho, Umberto Manera, Eleonora Tavazzi, Giorgio Maria Di Nunzio, Gianmaria Silvello, Nicola Ferro
Publikováno v:
Journal of Biomedical Semantics, Vol 15, Iss 1, Pp 1-28 (2024)
Abstract Automatic disease progression prediction models require large amounts of training data, which are seldom available, especially when it comes to rare diseases. A possible solution is to integrate data from different medical centres. Neverthel
Externí odkaz:
https://doaj.org/article/011335de1b1f4ba89b746177d99a618b
Autor:
Laura Menotti, Gianmaria Silvello, Manfredo Atzori, Svetla Boytcheva, Francesco Ciompi, Giorgio Maria Di Nunzio, Filippo Fraggetta, Fabio Giachelle, Ornella Irrera, Stefano Marchesin, Niccolò Marini, Henning Müller, Todor Primov
Publikováno v:
Journal of Pathology Informatics, Vol 14, Iss , Pp 100332- (2023)
Computational pathology can significantly benefit from ontologies to standardize the employed nomenclature and help with knowledge extraction processes for high-quality annotated image datasets. The end goal is to reach a shared model for digital pat
Externí odkaz:
https://doaj.org/article/81eb50cf871b4bf3a039110465600863
Autor:
Irene Appolloni, Francesco Alessandrini, Laura Menotti, Elisa Avitabile, Daniela Marubbi, Noemi Piga, Davide Ceresa, Francesca Piaggio, Gabriella Campadelli-Fiume, Paolo Malatesta
Publikováno v:
Viruses, Vol 13, Iss 9, p 1677 (2021)
Glioblastoma is a lethal primary brain tumor lacking effective therapy. The secluded onset site, combined with the infiltrative properties of this tumor, require novel targeted therapies. In this scenario, the use of oncolytic viruses retargeted to g
Externí odkaz:
https://doaj.org/article/b7dd1094c00f4911a95be6a185347435
HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses
Autor:
Laura Menotti, Elisa Avitabile, Valentina Gatta, Paolo Malatesta, Biljana Petrovic, Gabriella Campadelli-Fiume
Publikováno v:
Viruses, Vol 10, Iss 7, p 352 (2018)
Previously, we engineered oncolytic herpes simplex viruses (o-HSVs) retargeted to the HER2 (epidermal growth factor receptor 2) tumor cell specific receptor by the insertion of a single chain antibody (scFv) to HER2 in gD, gH, or gB. Here, the insert
Externí odkaz:
https://doaj.org/article/ec7d766dfd494b459dc59a0ebec1d49d
Publikováno v:
Emerging Infectious Diseases, Vol 5, Iss 3, Pp 353-366 (1999)
Infections with human herpesvirus 6 (HHV-6), a ß-herpesvirus of which two variant groups (A and B) are recognized, is very common, approaching 100% in seroprevalence. Primary infection with HHV-6B causes roseola infantum or exanthem subitum, a commo
Externí odkaz:
https://doaj.org/article/418e2f0c79894fc2ae76635b3484e166
Autor:
Patrizia Nanni, Valentina Gatta, Laura Menotti, Carla De Giovanni, Marianna Ianzano, Arianna Palladini, Valentina Grosso, Massimiliano Dall'ora, Stefania Croci, Giordano Nicoletti, Lorena Landuzzi, Manuela Iezzi, Gabriella Campadelli-Fiume, Pier-Luigi Lollini
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003155 (2013)
Oncolytic viruses aim to specifically kill tumor cells. A major challenge is the effective targeting of disseminated tumors in vivo. We retargeted herpes simplex virus (HSV) tropism to HER-2 oncoprotein p185, overexpressed in ovary and breast cancers
Externí odkaz:
https://doaj.org/article/45fe9d4027634cfe86e1eaff9514f27a
Autor:
Gabriella Campadelli-Fiume, Noemi Piga, Irene Appolloni, Francesca Piaggio, Elisa Avitabile, Paolo Malatesta, Francesco Alessandrini, Davide Ceresa, Daniela Marubbi, Laura Menotti
Publikováno v:
Viruses
Viruses, Vol 13, Iss 1677, p 1677 (2021)
Volume 13
Issue 9
Viruses, Vol 13, Iss 1677, p 1677 (2021)
Volume 13
Issue 9
Glioblastoma is a lethal primary brain tumor lacking effective therapy. The secluded onset site, combined with the infiltrative properties of this tumor, require novel targeted therapies. In this scenario, the use of oncolytic viruses retargeted to g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe2fdf6d231662f687ae3626c77f47b
http://europepmc.org/articles/PMC8473268
http://europepmc.org/articles/PMC8473268
Autor:
Tatiana Gianni, Laura Menotti, Valentina Gatta, Simona Pepe, Biljana Petrovic, Gabriella Campadelli-Fiume, Andrea Vannini, Valerio Leoni
Publikováno v:
Methods in Molecular Biology ISBN: 9781493998135
In the previous chapter, we describe the engineering of a HSV-BAC genome by galK recombineering. Here we describe the procedures to reconstitute, or regenerate, the replicating recombinant virus, and the methods to purify it and characterize it for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fc8e13548fa6064db08eefb311282c
https://doi.org/10.1007/978-1-4939-9814-2_8
https://doi.org/10.1007/978-1-4939-9814-2_8
Autor:
Andrea Vannini, Tatiana Gianni, Laura Menotti, Valerio Leoni, Biljana Petrovic, Simona Pepe, Gabriella Campadelli-Fiume, Valentina Gatta
Publikováno v:
Methods in Molecular Biology ISBN: 9781493998135
Since the cloning of the herpes simplex virus (HSV) genome as BAC (bacterial artificial chromosome), the genetic engineering of the viral genome has become readily feasible. The advantage is that the modification of the animal virus genome is carried
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf368905510505cc9eb349fe747cd8e9
https://doi.org/10.1007/978-1-4939-9814-2_7
https://doi.org/10.1007/978-1-4939-9814-2_7
Autor:
Laura Menotti, Elisa Avitabile
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8310, p 8310 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Oncolytic viruses are smart therapeutics against cancer due to their potential to replicate and produce the needed therapeutic dose in the tumor, and to their ability to self-exhaust upon tumor clearance. Oncolytic virotherapy strategies based on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cea620bad6f77d99f7a90c3222a966
https://www.mdpi.com/1422-0067/21/21/8310
https://www.mdpi.com/1422-0067/21/21/8310