Epigenetic and 3D genome reprogramming during the aging of human hippocampus.

Autor: Zemke NR; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA.; Center for Epigenomics, University of California, San Diego School of Medicine; La Jolla, CA, USA., Lee S; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA., Mamde S; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA., Yang B; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA.; Center for Epigenomics, University of California, San Diego School of Medicine; La Jolla, CA, USA., Berchtold N; Department of Anatomy and Neurobiology, University of California, Irvine School of Medicine; Irvine, CA, USA.; Immunis Inc, 18301 Von Karman Ave; Irvine, CA, USA., Maximiliano Garduño B; Department of Anatomy and Neurobiology, University of California, Irvine School of Medicine; Irvine, CA, USA., Indralingam HS; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA.; Center for Epigenomics, University of California, San Diego School of Medicine; La Jolla, CA, USA., Bartosik WM; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA.; Center for Epigenomics, University of California, San Diego School of Medicine; La Jolla, CA, USA., Lau PK; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA.; Center for Epigenomics, University of California, San Diego School of Medicine; La Jolla, CA, USA., Dong K; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA.; Center for Epigenomics, University of California, San Diego School of Medicine; La Jolla, CA, USA., Yang A; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA., Tani Y; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA., Chen C; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA., Zeng Q; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA., Ajith V; Department of Anatomy and Neurobiology, University of California, Irvine School of Medicine; Irvine, CA, USA., Tong L; Department of Anatomy and Neurobiology, University of California, Irvine School of Medicine; Irvine, CA, USA., Seng C; Department of Genetics, The Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine; St. Louis, MO, USA., Li D; Department of Genetics, The Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine; St. Louis, MO, USA., Wang T; Department of Genetics, The Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine; St. Louis, MO, USA.; McDonnell Genome Institute, Washington University School of Medicine; St. Louis, MO, USA., Xu X; Department of Anatomy and Neurobiology, University of California, Irvine School of Medicine; Irvine, CA, USA.; The Center for Neural Circuit Mapping, University of California; Irvine, CA, USA., Ren B; Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine; La Jolla, CA, USA.; Center for Epigenomics, University of California, San Diego School of Medicine; La Jolla, CA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 17. Date of Electronic Publication: 2024 Oct 17.

Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer.

Autor: Hoon SN; Medical Oncology Department, St John of God Midland, Perth, Australia.; Medical Oncology Department, Sir Charles Gairdner Hospital, Perth, Australia., Lau PK; Medical Oncology Department, Sir Charles Gairdner Hospital, Perth, Australia.; Medical Oncology Department, Peter MacCallum Cancer Centre, Melbourne, Australia., White AM; Murdoch Community Hospice, St John of God Hospital Murdoch, Perth, Australia.; Palliative Care Department, Royal Perth Hospital, Perth, Australia., Bulsara MK; Institute for Health Research, University of Notre Dame Australia, Fremantle, Australia.; School of Population and Global Health, The University of Western Australia, Perth, Australia.; Division of Surgery and Interventional Science, University College London, London, UK., Banks PD; Medical Oncology Department, Peter MacCallum Cancer Centre, Melbourne, Australia.; Medical Oncology Department, University Hospital Geelong, Geelong, Australia., Redfern AD; School of Medicine, University of Western Australia, Perth, Australia.; Medical Oncology Department, Fiona Stanley Hospital, Perth, Australia.

Publikováno v: The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2021 May 26; Vol. 5. Cochrane AN: CD011220. Date of Electronic Publication: 2021 May 26.

Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction.

Autor: Chan RWY; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Serpas L; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Ni M; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Volpi S; Clinica Pediatrica e Reumatologia, Centro per le malattie Autoinfiammatorie e Immunodeficienze, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Giannina Gaslini, Via G. Gaslini 5, 16147 Genova, Italy; Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DINOGMI), Università degli Studi di Genova, 16132 Genova, Italy., Hiraki LT; Division of Rheumatology, The Hospital for Sick Children, Toronto, ON M5G 1X5, Canada., Tam LS; Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Rashidfarrokhi A; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Wong PCH; Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Tam LHP; Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Wang Y; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Jiang P; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Cheng ASH; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Peng W; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Han DSC; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Tse PPP; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Lau PK; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Lee WS; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Magnasco A; Division of Nephrology, Dialysis and Transplantation, Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Giannina Gaslini, 16147 Genova, Italy., Buti E; Nefrologia e Dialisi, Azienda Ospedaliero Universitaria Meyer, 50139 Firenze, Italy., Sisirak V; CNRS-UMR 5164, ImmunoConcEpt, Université de Bordeaux, 33076 Bordeaux, France., AlMutairi N; Sabah Hospital, Jaber Al Ahmad Al Jaber Al Sabah Hospital, Kuwait., Chan KCA; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Chiu RWK; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China., Reizis B; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA. Electronic address: boris.reizis@nyulangone.org., Lo YMD; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China. Electronic address: loym@cuhk.edu.hk.

Publikováno v: American journal of human genetics [Am J Hum Genet] 2020 Nov 05; Vol. 107 (5), pp. 882-894. Date of Electronic Publication: 2020 Oct 05.

The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking.

Autor: Mao Y; PKU-THU Joint Center for Life Sciences, College of Life Sciences, School of Medical Sciences, Tsinghua University, Beijing 100084, China., Tu R; Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA., Huang Y; Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China., Mao D; PKU-THU Joint Center for Life Sciences, College of Life Sciences, School of Medical Sciences, Tsinghua University, Beijing 100084, China., Yang Z; PKU-THU Joint Center for Life Sciences, College of Life Sciences, School of Medical Sciences, Tsinghua University, Beijing 100084, China., Lau PK; Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China., Wang J; Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China., Ni J; PKU-THU Joint Center for Life Sciences, College of Life Sciences, School of Medical Sciences, Tsinghua University, Beijing 100084, China nijq@mail.tsinghua.edu.cn guoyusong@ust.hk tgx@stowers.org., Guo Y; Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China nijq@mail.tsinghua.edu.cn guoyusong@ust.hk tgx@stowers.org., Xie T; Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA nijq@mail.tsinghua.edu.cn guoyusong@ust.hk tgx@stowers.org.

Publikováno v: Development (Cambridge, England) [Development] 2019 Jun 28; Vol. 146 (13). Date of Electronic Publication: 2019 Jun 28.

A mechanism for differential sorting of the planar cell polarity proteins Frizzled6 and Vangl2 at the trans -Golgi network.

Autor: Ma T; From the Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China., Li B; the Centre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Wang R; the Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, and., Lau PK; From the Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China., Huang Y; From the Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China., Jiang L; the Centre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Schekman R; the Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, and., Guo Y; From the Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China, guoyusong@ust.hk.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2018 Jun 01; Vol. 293 (22), pp. 8410-8427. Date of Electronic Publication: 2018 Apr 17.