Výsledky vyhledávání - "LATRONICO MV"

Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure

Autor: Francesco Borgia, Philip Jones, Raffaele De Francesco, Pasquale Gallo, Michael V.G. Latronico, Christian Steinkühler, Paola Gallinari, Paolo Gallo, Serena Grimaldi, Matilde Todaro, Giovanni Esposito, Gianluigi Condorelli, Gennaro Ciliberto

Publikováno v: Cardiovascular Research. 80:416-424

AIMS: Recent studies have demonstrated the importance of chromatin remodelling via histone acetylation/deacetylation for the control of cardiac gene expression. Specific histone deacetylases (HDACs) can, in fact, play a positive or negative role in d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc9e731c63f7da9da11b20596038354
https://doi.org/10.1093/cvr/cvn215

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Circulating miR-29a, Among Other Up-Regulated MicroRNAs, Is the Only Biomarker for Both Hypertrophy and Fibrosis in Patients With Hypertrophic Cardiomyopathy

Autor: Giovanni Esposito, Laura Papa, Laura Galastri, Massimo Imbriaco, Carla Contaldi, Gianluigi Condorelli, Michael V.G. Latronico, Roberta Roncarati, Gloria Saccani Jotti, Paula A. da Costa Martins, Maria Angela Losi, Sandro Betocchi, Chiara Viviani Anselmi, Elena Cavarretta, Leon J. De Windt, Anna Franzone

Publikováno v: Journal of the American College of Cardiology
Journal of the American College of Cardiology, 63(9), 920-927. Elsevier Science

Objectives The purpose of this paper was to determine whether microRNAs (miRNAs) involved in myocardial remodeling were differentially expressed in the blood of hypertrophic cardiomyopathy (HCM) patients, and whether circulating miRNAs correlated wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51987ca0a6644ec85b7e49d195880e77
https://doi.org/10.1016/j.jacc.2013.09.041

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Th1 and Th2 cytokines exert regulatory effects upon islet microvascular areas in the NOD mouse

Autor: Michael V.G. Latronico, Francesco Aurelio Pisanti, Rosita Di Montefiano, Gianpaolo Papaccio, Antonio Graziano

Publikováno v: Journal of Cellular Biochemistry. 86:651-664

In this study, we show that intra- and peri-islet microvascular areas undergo different changes during the islet inflammation in the nonobese diabetes-prone female mice. Actually, although the islet vascular area (IVA) considerably decreases while th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d505f4d574408554354d97ff91b310e
https://doi.org/10.1002/jcb.10250

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'Unexpectedly Low Mutation Rates in beta-Myosin Heavy Chain and Cardiac Myosin Binding Protein Genes in Italian Patients with Hypertrophic Cardiomyopathy.'

Autor: Roberta Roncarati, 1, 2 Michael VG Latronico, 2 Beatrice Musumeci, 3 Stefania Aurino, 4 Annalaura Torella, 5 Marie-Louise Bang, 2, 6 Gloria Saccani Jotti, 7 Annibale A Puca, 2 Massimo Volpe, 3 Vincenzo Nigro, 4, 5 Camillo Autore, 3, Gianluigi Condorelli2, 8

Publikováno v: Journal of cellular physiology (Online) 226 (2011): 2894–2900. doi:10.1002/jcp.22636
info:cnr-pdr/source/autori:Roberta Roncarati,1,2 Michael VG Latronico,2 Beatrice Musumeci,3 Stefania Aurino,4 Annalaura Torella,5 Marie-Louise Bang,2,6 Gloria Saccani Jotti,7 Annibale A Puca,1,2 Massimo Volpe,3 Vincenzo Nigro,4,5 Camillo Autore,3 and Gianluigi Condorelli2,8,*/titolo:"Unexpectedly Low Mutation Rates in beta-Myosin Heavy Chain and Cardiac Myosin Binding Protein Genes in Italian Patients with Hypertrophic Cardiomyopathy."/doi:10.1002%2Fjcp.22636/rivista:Journal of cellular physiology (Online)/anno:2011/pagina_da:2894/pagina_a:2900/intervallo_pagine:2894–2900/volume:226
Journal of Cellular Physiology

Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease. Fourteen sarcomeric and sarcomere-related genes have been implicated in HCM etiology, those encoding β-myosin heavy chain (MYH7) and cardiac myosin binding protein C (MYBP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da39037ec5600fd0f350e871dbc74c6e

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Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

Autor: Junichi Sadoshima, Yusu Gu, Michael V.G. Latronico, Roberta Roncarati, Giorgio Stassi, John Ross, Clarence Chung, Carlo M. Croce, Alessandra Drusco, Matteo Antonio Russo, Gianluigi Condorelli, Claudio Napoli, Alfonso Bellacosa, Nancy D. Dalton, Guido Iaccarino

The serine-threonine kinase Akt seems to be central in mediating stimuli from different classes of receptors. In fact, both IGF-1 and IL6-like cytokines induce hypertrophic and antiapoptotic signals in cardiomyocytes through PI3K-dependent Akt activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca55ece65f091c05076c360f25fbade
https://europepmc.org/articles/PMC129445/

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Adhesion molecules and microvascular changes in the nonobese diabetic (NOD) mouse pancreas. An NO-inhibitor (L-NAME) is unable to block adhesion inflammation-induced activation

Autor: Francesco Aurelio Pisanti, Konrad Federlin, Gianpaolo Papaccio, Thomas Linn, Michael V.G. Latronico

Publikováno v: Scopus-Elsevier

The aim of the present study was to investigate the immunoreactivity of pancreatic microvasculature with emphasis on the adhesion molecule expression in NOD mice at a very early stage and after the start of infiltration, before the onset of the diabe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817ec7bffffd5af293f12cb7f7713738
http://hdl.handle.net/11591/190786

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