Výsledky vyhledávání - "LARRY E. RODMAN"

Acute and Chronic Administration of Ibogaine to the Rat Results in Astrogliosis That Is Not Confined to the Cerebellar Vermise

Autor: Larry E. Rodman, John G. Page, James P. O'Callaghan, Tina S. Rogers

Publikováno v: Annals of the New York Academy of Sciences. 801:205-216

Acute administration of high doses of ibogaine (IBG) to the male rat results in degeneration of Purkinje cells and reactive gliosis in the cerebellar vermis. We examined whether acute and chronic administration of IBG to male and female rats results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4cf8193df4dcfc08eb752ad359cc3e
https://doi.org/10.1111/j.1749-6632.1996.tb17443.x

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3,3′,4,4′-Tetrabromobiphenyl sensitizes rats to the hepatotoxic effects of endotoxin by a mechanism that involves more than tumor necrosis factor

Autor: Farrel R. Robinson, Steven I. Shedlofsky, Larry W. Robertson, Alice T. Swim, Craig J. McClain, Larry E. Rodman, Niel C. Hoglen, Ron Honchel

Publikováno v: Hepatology. 14:1201-1208

To determine whether the cytokine tumor necrosis factor/cachectin might be a mediator of hepatotoxicity seen after exposure to polyhalogenated aromatic hydrocarbons, rats treated with a single dose of 3,3′,4,4′-tetrabromobiphenyl (150 μmol/kg in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f4a4e4b6568ceb503a9ebf204a98c0b
https://doi.org/10.1002/hep.1840140640

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Differential potency of atropisomers of polychlorinated biphenyls on cytochrome P450 induction and uroporphyrin accumulation in the chick embryo hepatocyte culture

Autor: Albrecht Mannschreck, Michael Püttmann, Larry E. Rodman, Alice T. Swim, Steven I. Shedlofsky, Larry W. Robertson

Publikováno v: Biochemical Pharmacology. 41:915-922

The atropisomers of 2,2',3,4,6-pentachlorobiphenyl (PeCB), 2,2',3,4,4',6-hexachlorobiphenyl (HeCB), and 2,2',3,3',4,4',6,6'-octachlorobiphenyl (OCB) were studied in the chick embryo hepatocyte culture to determine if chirality plays a role in the rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d7fee884e93db28379199c50e227fa
https://doi.org/10.1016/0006-2952(91)90196-c

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Toxicity of cordycepin in combination with the adenosine deaminase inhibitor 2'-deoxycoformycin in beagle dogs

Autor: Larry E. Rodman, Donald L. Hill, Joseph E. Tomaszewski, Daniel R. Farnell, Kimberly L.K. Duncan, John G. Page, Paula W. Allan, Adaline C. Smith, John M. Coyne

Publikováno v: Toxicology and applied pharmacology. 147(1)

For 3 consecutive days, the nucleoside cordycepin (3'-deoxyadenosine) was administered as 1-hr iv infusions (0, 1, 4, 8, 10, or 20 mg/kg/day) to dogs. These doses were given 1 hr after a bolus iv injection (0.25 mg/kg/day) of 2'-deoxycoformycin (dCF)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e28cf802295a9c3d0c589510271f29
https://pubmed.ncbi.nlm.nih.gov/9356305

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Chronic toxicity studies of 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione, a potential chemopreventive agent

Autor: James A. Crowell, Larry E. Rodman, John G. Page, Gary J. Kelloff, Edwin I. Goldenthal, James E. Heath, Leroy B. Hall

Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 35(1)

The synthetic compound Oltipraz, 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione, is related to the 1,2-dithiolthiones naturally found in cruciferous vegetables, the consumption of which has been epidemiologically associated with reduced frequency of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c9110800eb5ca4b6b31aa3a5286520
https://pubmed.ncbi.nlm.nih.gov/9024669

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Carbon-13 NMR chemical shift—Substituent effect correlations in substituted styrenes

Autor: Chung R Chang, James L Fritzsche, Larry E Rodman, John M Franceschini, John E Hamilton, Forrest C Ward, Dale W Norris, Gregory E. Stablein, John M Morris, Charles N. Robinson, Vernon I Smith, Charles C. Irving, Louise S Dewey, John S Covington, Carl D. Slater

Publikováno v: Journal of Magnetic Resonance (1969). 41:293-301

Carbon-13 chemical shifts are reported for various atoms in 12 series of substituted styrenes. The reliability of the correlations between substituent effects on such shifts and σ+ values is discussed, as is the reliability of the use of a σ+ scale

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d5c823178c9788c7d7aeb1bcbaf4d4a
https://doi.org/10.1016/0022-2364(80)90076-1

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Effects of polychlorinated biphenyls on cytochrome P450 induction in the chick embryo hepatocyte culture

Autor: Larry E. Rodman, Larry W. Robertson, Alice T. Swim, Steven I. Shedlofsky

Publikováno v: Archives of Biochemistry and Biophysics. 275:252-262

The effects of pure synthetic polychlorinated biphenyl (PCB) congeners on the induction of cytochrome P450 and associated activities were examined in cultured chick embryo hepatocytes. Dose-response effects for the induction of total cytochrome P450,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4bbaff5fa7b490ff344c65ee8fa60e
https://doi.org/10.1016/0003-9861(89)90371-8

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