Zobrazeno 1 - 10
of 275
pro vyhledávání: '"LAMP2A"'
Autor:
Wen Li, Mengting Zhang, Yueshuai Wang, Shijie Zhao, Pengli Xu, Zhiying Cui, Jing Chen, Pingan Xia, Yina Zhang
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Autophagy is an important biological process in host defense against viral infection. However, many viruses have evolved various strategies to disrupt the host antiviral system. Porcine reproductive and respiratory syndrome virus (PRRSV) is
Externí odkaz:
https://doaj.org/article/6175cacf23b44a0a9db729560e4dd887
Autor:
Kensuke Motomura, Erika Ueda, Alex Boateng, Masaharu Sugiura, Keiichi Kadoyama, Natsuko Hitora-Imamura, Yuki Kurauchi, Hiroshi Katsuki, Takahiro Seki
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Introduction: Aromatic (Ar)-turmerone is a bioactive component of turmeric oil obtained from Curcuma longa. We recently identified a novel analog (A2) of ar-turmerone that protects dopaminergic neurons from toxic stimuli by activating nuclear factor
Externí odkaz:
https://doaj.org/article/d9db6cc762ad412d96ad6591a73bf799
Autor:
Tetsumori Yamashima, Daria Mochly-Rosen, Soichi Wakatsuki, Eishiro Mizukoshi, Takuya Seike, Isabel Maria Larus, Che-Hong Chen, Miho Takemura, Hisashi Saito, Akihiro Ohashi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Autophagy mediates the degradation of intracellular macromolecules and organelles within lysosomes. There are three types of autophagy: macroautophagy, microautophagy, and chaperone-mediated autophagy. Heat shock protein 70.1 (Hsp70.1) exhibits dual
Externí odkaz:
https://doaj.org/article/eee398e828314d8f9bda7fabb7eb97e6
Autor:
Mirko Maglica, Nela Kelam, Ilija Perutina, Anita Racetin, Azer Rizikalo, Natalija Filipović, Ivana Kuzmić Prusac, Josip Mišković, Katarina Vukojević
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6829 (2024)
The purpose of this study was to evaluate the spatiotemporal immunoexpression pattern of microtubule-associated protein 1 light chain 3 beta (LC3B), glucose-regulated protein 78 (GRP78), heat shock protein 70 (HSP70), and lysosomal-associated membran
Externí odkaz:
https://doaj.org/article/3bd51269325e4f0fa0376f7b2730564c
Autor:
Rajeshwary Ghosh, J. Scott Pattison
Publikováno v:
Autophagy Reports, Vol 2, Iss 1 (2023)
Externí odkaz:
https://doaj.org/article/5115cff6dc28475b94ed9a65d6c0ecfd
Autor:
Azer Rizikalo, Mirko Maglica, Nela Kelam, Ilija Perutina, Marin Ogorevc, Anita Racetin, Natalija Filipović, Yu Katsuyama, Zdenka Zovko, Josip Mišković, Katarina Vukojević
Publikováno v:
Life, Vol 14, Iss 3, p 316 (2024)
The purpose of this study was to evaluate the effects of Dab1 gene silencing on the immunoexpression of light chain 3 beta (Lc3b), glucose regulating protein 78 (Grp78), heat shock cognate 71 (Hsc70), mammalian target of rapamycin (mTOR) and lysosoma
Externí odkaz:
https://doaj.org/article/493ebfa43cae483a88ea407d9434f76b
Autor:
Gianna M. Fote, Joan S. Steffan
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 29-33 (2022)
Human APOE4 (apolipoprotein E4 isoform) is a powerful genetic risk factor for late-onset Alzheimer disease (AD). Many groups have investigated the effect of APOE4 on the degradation of amyloid β (Aβ), the main component of plaques found in the brai
Externí odkaz:
https://doaj.org/article/6dfde4e7733d4991b741280568a10632
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 205-209 (2022)
Chaperone-mediated autophagy (CMA) is a unique proteolytic pathway, in which cytoplasmic proteins recognized by HSPA8/Hsc70 (heat shock protein 8) are transported into lysosomes for degradation. LAMP2A (lysosomal-associated membrane protein 2A) recru
Externí odkaz:
https://doaj.org/article/0403bdb1e17d47d1a55f0df69dd752a5
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Akademický článek
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