Zobrazeno 1 - 10
of 52
pro vyhledávání: '"LAMBERT, C. M."'
Autor:
Michael L. Gross, Lambert C. M. Ngoka
Publikováno v:
Journal of Mass Spectrometry. 35:265-276
We previously showed by using mass spectrometry that endothelin A selective receptor antagonists BQ123 and JKC301 form novel coordination compounds with sodium ions. This property may underlie the ability of an ETA antagonist to induce net tubular so
Autor:
Michael L. Gross, Lambert C. M. Ngoka
Publikováno v:
International Journal of Mass Spectrometry. 194:247-259
Evidence from collisionally activated decomposition (CAD) of electrospray-produced ions in an ion trap shows that lithium ion binds to the backbone ester oxygen atoms of valinomycin to open the cyclodepsipeptide ring at the D-α-hydroxyvaleric acid a
Autor:
Michael L. Gross, Lambert C. M. Ngoka
Publikováno v:
Journal of the American Society for Mass Spectrometry. 10:360-363
A nomenclature system for labeling fragment ions of cyclic peptides is proposed. A fragment ion is labeled with a four-part descriptor of the general formula xnJZ, where x is the designation for the ion (e.g., lower case a or b, as are used for pepti
Publikováno v:
International Journal of Mass Spectrometry. :289-298
A strategy is presented for the determination of amino-acid sequences of cyclodepsipeptide antibiotics. A highly specific sodium-ion interaction with the backbone lactone opens the depsipeptide ring to form a linear acylium ion or isomeric equivalent
Autor:
Lambert C. M. Ngoka
Publikováno v:
Proteome Science, Vol 6, Iss 1, p 29 (2008)
Proteome Science
Proteome Science
Background Oxidoreductases are enzymes that catalyze many redox reactions in normal and neoplastic cells. Their actions include catalysis of the transformation of free, neutral oxygen gas into oxygen free radicals, superoxide, hydroperoxide, singlet
Publikováno v:
Biomedical chromatography : BMC. 20(8)
The formation of multiple molecular ions, especially due to sodium adduct ion formation, is commonly observed in electrospray mass spectrometry and may make reproducible and sensitive quantitation difficult. The objective of this work was to investig
Autor:
Michael L. Gross, Lambert C. M. Ngoka
Publikováno v:
Journal of the American Society for Mass Spectrometry. 10(8)
Collisionally activated decomposition (CAD) of a protonated cyclic peptide produces a superposition spectrum consisting of fragments produced following random ring opening of the cyclic peptide to give a set of acylium ions (or isomeric equivalents)
Autor:
Michael L. Gross, Lambert C. M. Ngoka
Publikováno v:
Biochemical and biophysical research communications. 254(3)
Electrospray ionization and fast atom bombardment mass spectrometric methods reveal novel interactions of endothelin A selective receptor antagonists, cyclo(D-Trp-D-Asp-Pro-D-Val-Leu), cyclo(D-Trp-D-Glu-Ala-D-allo-Ile-Leu) and cyclo(D-Trp-D-Asp-Pro-D
Publikováno v:
SPIE Proceedings.
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), because of its high sensitivity and relatively straightforward requirements for sample preparation, is contributing to the solution of structural problems in