Circulating KRAS G12D but not G12V is associated with survival in metastatic pancreatic ductal adenocarcinoma

Autor: Jacob E. Till, Lee McDaniel, Changgee Chang, Qi Long, Shannon M. Pfeiffer, Jaclyn P. Lyman, Lacey J. Padrón, Deena M. Maurer, Jia Xin Yu, Christine N. Spencer, Pier Federico Gherardini, Diane M. Da Silva, Theresa M. LaVallee, Charles Abbott, Richard O. Chen, Sean M. Boyle, Neha Bhagwat, Samuele Cannas, Hersh Sagreiya, Wenrui Li, Stephanie S. Yee, Aseel Abdalla, Zhuoyang Wang, Melinda Yin, Dominique Ballinger, Paul Wissel, Jennifer Eads, Thomas Karasic, Charles Schneider, Peter O’Dwyer, Ursina Teitelbaum, Kim A. Reiss, Osama E. Rahma, George A. Fisher, Andrew H. Ko, Zev A. Wainberg, Robert A. Wolff, Eileen M. O’Reilly, Mark H. O’Hara, Christopher R. Cabanski, Robert H. Vonderheide, Erica L. Carpenter

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)

Abstract While high circulating tumor DNA (ctDNA) levels are associated with poor survival for multiple cancers, variant-specific differences in the association of ctDNA levels and survival have not been examined. Here we investigate KRAS ctDNA (ctKR

Externí odkaz: https://doaj.org/article/4f9cd688d606493b979047418e6f71a0

Mammary Myofibroblastoma: A mimicker of benign and low-grade malignant tumors with multipotent mesenchymal differentiation

Autor: Anthony S. Larson, Amy Song, Lacey J. Schrader, Mark Wickre, Grzegorz T Gurda

Publikováno v: Current Problems in Cancer: Case Reports, Vol 15, Iss , Pp 100310- (2024)

Mammary myofibroblastoma (MFB) is a rare benign spindle cell neoplasm of the breast that can exhibit both epithelial and mesenchymal elements. The histomorphologic features of MFB mimic other potentially more aggressive neoplasms of the breast that m

Externí odkaz: https://doaj.org/article/569c78e8a18d45fe935c1bcdc34feb1e

Clinical pharmacist intervention to ensure safe stimulant prescribing practices at a Veterans Affairs facility

Autor: Bailey B. Bass, PharmD, BCPS, Lacey J. Vann, PharmD, BCPP

Publikováno v: Mental Health Clinician, Vol 14, Iss 1, Pp 17-22 (2024)

Introduction The Psychotropic Drug Safety Initiative (PDSI) is a national Veterans Affairs program that recommends obtaining cardiovascular vital signs semiannually and urine toxicology screening annually for veterans prescribed stimulants. The PDSI

Externí odkaz: https://doaj.org/article/38acf962d58247a6a6b88124facc314e

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On the interconnected nature of risk and responsibility in the research and development of new and emerging technologies.

Autor: Malakar Y; Responsible Innovation Future Science Platform, Commonwealth Scientific and Industrial Research Organisation, Brisbane, Queensland, Australia., Lacey J; Responsible Innovation Future Science Platform, Commonwealth Scientific and Industrial Research Organisation, Brisbane, Queensland, Australia.

Publikováno v: Risk analysis : an official publication of the Society for Risk Analysis [Risk Anal] 2024 Jun; Vol. 44 (6), pp. 1325-1338. Date of Electronic Publication: 2023 Sep 25.