Zobrazeno 1 - 10
of 1 349
pro vyhledávání: '"LACEY, E."'
Autor:
Awasthi, Sharad 1, 17, ∗, Dobrolecki, Lacey E. 2, Sallas, Christina 2, Zhang, Xudong 3, Li, Yang 1, Khazaei, Sima 1, Ghosh, Sumanta 1, Jeter, Collene R. 1, Liu, Jinsong 3, Mills, Gordon B. 4, Westin, Shannon N. 5, Lewis, Michael T. 2, Peng, Weiyi 6, Sood, Anil K. 5, Yap, Timothy A. 7, Yi, S. Stephen 8, 9, 10, 11, McGrail, Daniel J. 12, 13, 16, ∗∗, Sahni, Nidhi 1, 14, 15, 16
Publikováno v:
In Cell Reports Medicine 17 December 2024 5(12)
Autor:
Xu, Longyong, Peng, Fanglue, Luo, Qin, Ding, Yao, Yuan, Fei, Zheng, Liting, He, Wei, Zhang, Sophie S., Fu, Xin, Liu, Jin, Mutlu, Ayse Sena, Wang, Shuyue, Nehring, Ralf Bernd, Li, Xingyu, Tang, Qianzi, Li, Catherine, Lv, Xiangdong, Dobrolecki, Lacey E., Zhang, Weijie, Han, Dong, Zhao, Na, Jaehnig, Eric, Wang, Jingyi, Wu, Weiche, Graham, Davis A., Li, Yumei, Chen, Rui, Peng, Weiyi, Chen, Yiwen, Catic, Andre, Zhang, Zhibin, Zhang, Bing, Mustoe, Anthony M., Koong, Albert C., Miles, George, Lewis, Michael T., Wang, Meng C., Rosenberg, Susan M., O’Malley, Bert W., Westbrook, Thomas F., Xu, Han, Zhang, Xiang H.-F., Osborne, C. Kent, Li, Jin Billy, Ellis, Matthew J., Rimawi, Mothaffar F., Rosen, Jeffrey M., Chen, Xi
Publikováno v:
In Cell 12 December 2024 187(25):7248-7266
Autor:
Lim, Bora, Seth, Sahil, Yam, Clinton, Huo, Lei, Fujii, Takeo, Lee, Jangsoon, Bassett, Roland, Nasser, Sara, Ravenberg, Lisa, White, Jason, Clayborn, Alyson, Guerra, Gil, Litton, Jennifer K., Damodaran, Senthil, Layman, Rachel, Valero, Vicente, Tripathy, Debasish, Lewis, Michael, Dobrolecki, Lacey E., Lei, Jonathan, Candelaria, Rosalind, Arun, Banu, Rauch, Gaiane, Zhao, Li, Zhang, Jianhua, Ding, Qingqing, Symmans, W. Fraser, Chang, Jeffrey T., Thompson, Alastair M., Moulder, Stacy L., Ueno, Naoto T.
Publikováno v:
In Cell Reports Medicine 18 June 2024 5(6)
Autor:
Espinoza, Andres F., Patel, Roma H., Patel, Kalyani R., Badachhape, Andrew A., Whitlock, Richard, Srivastava, Rohit K., Govindu, Saiabhiroop R., Duong, Ashley, Kona, Abhishek, Kureti, Pavan, Armbruster, Bryan, Kats, Dina, Srinivasan, Ramakrishnan R., Dobrolecki, Lacey E., Yu, Xinjian, Najaf Panah, Mohammad J., Zorman, Barry, Sarabia, Stephen F., Urbicain, Martin, Major, Angela, Bissig, Karl-Dimiter, Keller, Charles, Lewis, Michael T., Heczey, Andras, Sumazin, Pavel, López-Terrada, Dolores H., Woodfield, Sarah E., Vasudevan, Sanjeev A.
Publikováno v:
In Journal of Hepatology April 2024 80(4):610-621
Autor:
Emel Alkim, Heidi Dowst, Julie DiCarlo, Lacey E. Dobrolecki, Anadulce Hernández-Herrera, David A. Hormuth, Yuxing Liao, Apollo McOwiti, Robia Pautler, Mothaffar Rimawi, Ashley Roark, Ramakrishnan Rajaram Srinivasan, Jack Virostko, Bing Zhang, Fei Zheng, Daniel L. Rubin, Thomas E. Yankeelov, Michael T. Lewis
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 810-828 (2023)
Co-clinical trials are the concurrent or sequential evaluation of therapeutics in both patients clinically and patient-derived xenografts (PDX) pre-clinically, in a manner designed to match the pharmacokinetics and pharmacodynamics of the agent(s) us
Externí odkaz:
https://doaj.org/article/e0d87f8b7a8e4f92951123a867d724ef
Autor:
Donna M. Peehl, Cristian T. Badea, Thomas L. Chenevert, Heike E. Daldrup-Link, Li Ding, Lacey E. Dobrolecki, A. McGarry Houghton, Paul E. Kinahan, John Kurhanewicz, Michael T. Lewis, Shunqiang Li, Gary D. Luker, Cynthia X. Ma, H. Charles Manning, Yvonne M. Mowery, Peter J. O'Dwyer, Robia G. Pautler, Mark A. Rosen, Raheleh Roudi, Brian D. Ross, Kooresh I. Shoghi, Renuka Sriram, Moshe Talpaz, Richard L. Wahl, Rong Zhou
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 657-680 (2023)
The availability of high-fidelity animal models for oncology research has grown enormously in recent years, enabling preclinical studies relevant to prevention, diagnosis, and treatment of cancer to be undertaken. This has led to increased opportunit
Externí odkaz:
https://doaj.org/article/315dd791b13b4c40966ef7abc8d61d4c
RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer
Autor:
Marina Ciscar, Eva M Trinidad, Gema Perez‐Chacon, Mansour Alsaleem, Maria Jimenez, Maria J Jimenez‐Santos, Hector Perez‐Montoyo, Adrian Sanz‐Moreno, Andrea Vethencourt, Michael Toss, Anna Petit, Maria T Soler‐Monso, Victor Lopez, Jorge Gomez‐Miragaya, Clara Gomez‐Aleza, Lacey E Dobrolecki, Michael T Lewis, Alejandra Bruna, Silvana Mouron, Miguel Quintela‐Fandino, Fatima Al‐Shahrour, Antonio Martinez‐Aranda, Angels Sierra, Andrew R Green, Emad Rakha, Eva Gonzalez‐Suarez
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 4, Pp 1-12 (2023)
Abstract Despite strong preclinical data, the therapeutic benefit of the RANKL inhibitor, denosumab, in breast cancer patients, beyond the bone, is unclear. Aiming to select patients who may benefit from denosumab, we hereby analyzed RANK and RANKL p
Externí odkaz:
https://doaj.org/article/1a7e932a6a184ce6a384d4a58e43a0be
Autor:
Oscar D Murillo, Varduhi Petrosyan, Emily L LaPlante, Lacey E Dobrolecki, Michael T Lewis, Aleksandar Milosavljevic
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1011365 (2023)
Proper characterization of cancer cell states within the tumor microenvironment is a key to accurately identifying matching experimental models and the development of precision therapies. To reconstruct this information from bulk RNA-seq profiles, we
Externí odkaz:
https://doaj.org/article/006f994a827e452db20048595c03626a
Autor:
Petrosyan, Varduhi, Dobrolecki, Lacey E., Thistlethwaite, Lillian, Lewis, Alaina N., Sallas, Christina, Srinivasan, Ramakrishnan R., Lei, Jonathan T., Kovacevic, Vladimir, Obradovic, Predrag, Ellis, Matthew J., Osborne, C. Kent, Rimawi, Mothaffar F., Pavlick, Anne, Shafaee, Maryam Nemati, Dowst, Heidi, Jain, Antrix, Saltzman, Alexander B., Malovannaya, Anna, Marangoni, Elisabetta, Welm, Alana L., Welm, Bryan E., Li, Shunqiang, Wulf, Gerburg M., Sonzogni, Olmo, Huang, Chen, Vasaikar, Suhas, Hilsenbeck, Susan G., Zhang, Bing, Milosavljevic, Aleksandar, Lewis, Michael T.
Publikováno v:
In iScience 20 January 2023 26(1)
Autor:
Varduhi Petrosyan, Lacey E. Dobrolecki, Emily L. LaPlante, Ramakrishnan Rajaram Srinivasan, Matthew H. Bailey, Alana L. Welm, Bryan E. Welm, Michael T. Lewis, Aleksandar Milosavljevic
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-5 (2022)
Abstract TNBC is a heterogeneous subtype of breast cancer, and only a subset of TNBC can be established as PDXs. Here, we show that there is an engraftment bias toward TNBC with low levels of immune cell infiltration. Additionally, TNBC that failed t
Externí odkaz:
https://doaj.org/article/df1189d5619f478396baf68cd383f8f1