Klinisches Ansprechen auf Ustekinumab beeinflusst bei Patienten mit Morbus Crohn dosisabhängig die Anzahl und Funktion von follikulären T Helferzellen

Autor: Robert Thimme, AM Globig, T Böttler, Maike Hofmann, Peter Hasselblatt, Anne K. Thomann, LA Schulte, W Reindl, Katharina Wild, Christoph M. Schempp, R Schreiner, J Klaus, N P Sommer

Publikováno v: Zeitschrift für Gastroenterologie.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a0abf6e20934a7019797fcc04fe49b8
https://doi.org/10.1055/s-0039-1695137

A US perspective on closing the carbon cycle to defossilize difficult-to-electrify segments of our economy.

Autor: Shaw WJ; Pacific Northwest National Laboratory, Richland, WA, USA. Wendy.shaw@pnnl.gov., Kidder MK; Oak Ridge National Laboratory, Oak Ridge, TN, USA. kidderm@ornl.gov., Bare SR; SLAC National Accelerator Laboratory, Menlo Park, CA, USA. srbare@slac.stanford.edu., Delferro M; Argonne National Laboratory, Lemont, IL, USA. delferro@anl.gov., Morris JR; Ames National Laboratory, Ames, IA, USA. morrisj@ameslab.gov., Toma FM; Lawrence Berkeley National Laboratory, Berkeley, CA, USA. fmtoma@lbl.gov.; Institute of Functional Materials for Sustainability, Helmholtz Zentrum Hereon, Teltow, Brandenburg, Germany. fmtoma@lbl.gov., Senanayake SD; Brookhaven National Laboratory, Upton, NY, USA. ssenanay@bnl.gov., Autrey T; Pacific Northwest National Laboratory, Richland, WA, USA., Biddinger EJ; Department of Chemical Engineering, The City College of New York, New York, NY, USA., Boettcher S; Lawrence Berkeley National Laboratory, Berkeley, CA, USA.; Department of Chemical & Biomolecular Engineering and Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA., Bowden ME; Pacific Northwest National Laboratory, Richland, WA, USA., Britt PF; Oak Ridge National Laboratory, Oak Ridge, TN, USA., Brown RC; Department of Mechanical Engineering, Iowa State University, Ames, IA, USA., Bullock RM; Pacific Northwest National Laboratory, Richland, WA, USA., Chen JG; Brookhaven National Laboratory, Upton, NY, USA.; Department of Chemical Engineering, Columbia University, New York, NY, USA., Daniel C; Argonne National Laboratory, Lemont, IL, USA., Dorhout PK; Vice President for Research, Iowa State University, Ames, IA, USA., Efroymson RA; Oak Ridge National Laboratory, Oak Ridge, TN, USA., Gaffney KJ; SLAC National Accelerator Laboratory, Menlo Park, CA, USA., Gagliardi L; Department of Chemistry, The University of Chicago, Chicago, IL, USA., Harper AS; Pacific Northwest National Laboratory, Richland, WA, USA., Heldebrant DJ; Pacific Northwest National Laboratory, Richland, WA, USA.; Chemical Engineering and Bioengineering, Washington State University, Pullman, WA, USA., Luca OR; Department of Chemistry, University of Colorado Boulder, Boulder, CO, USA., Lyubovsky M; Booz Allen Hamilton, Washington DC, USA., Male JL; Pacific Northwest National Laboratory, Richland, WA, USA.; Biological Systems Engineering Department, Washington State University, Pullman, WA, USA., Miller DJ; Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Prozorov T; Ames National Laboratory, Ames, IA, USA., Rallo R; Pacific Northwest National Laboratory, Richland, WA, USA., Rana R; Department of Chemical Engineering, University of California, Davis, CA, USA., Rioux RM; Department of Chemical Engineering, The Pennsylvania State University, University Park, PA, USA., Sadow AD; Ames National Laboratory, Ames, IA, USA.; Department of Chemistry, Iowa State University, Ames, IA, USA., Schaidle JA; National Renewable Energy Laboratory, Golden, CO, USA., Schulte LA; Department of Natural Resource Ecology and Management, Iowa State University, Ames, IA, USA., Tarpeh WA; Department of Chemical Engineering, Stanford University, Stanford, CA, USA., Vlachos DG; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, USA., Vogt BD; Department of Chemical Engineering, The Pennsylvania State University, University Park, PA, USA., Weber RS; Pacific Northwest National Laboratory, Richland, WA, USA., Yang JY; Department of Chemistry, University of California Irvine, Irvine, CA, USA., Arenholz E; Pacific Northwest National Laboratory, Richland, WA, USA., Helms BA; Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Huang W; Ames National Laboratory, Ames, IA, USA.; Department of Chemistry, Iowa State University, Ames, IA, USA., Jordahl JL; Department of Natural Resource Ecology and Management, Iowa State University, Ames, IA, USA., Karakaya C; Oak Ridge National Laboratory, Oak Ridge, TN, USA., Kian KC; Independent consultant, Washington DC, USA.; Department of Chemical Engineering, Worcester Polytechnic Institute, Worcester, MA, USA., Kothandaraman J; Pacific Northwest National Laboratory, Richland, WA, USA., Lercher J; Pacific Northwest National Laboratory, Richland, WA, USA.; Department of Chemistry, Technical University of Munich, Munich, Germany., Liu P; Brookhaven National Laboratory, Upton, NY, USA., Malhotra D; Pacific Northwest National Laboratory, Richland, WA, USA., Mueller KT; Pacific Northwest National Laboratory, Richland, WA, USA., O'Brien CP; Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN, USA., Palomino RM; BASF Corporation, Iselin, NJ, USA., Qi L; Ames National Laboratory, Ames, IA, USA., Rodriguez JA; Brookhaven National Laboratory, Upton, NY, USA., Rousseau R; Oak Ridge National Laboratory, Oak Ridge, TN, USA., Russell JC; Advanced Research Projects Agency - Energy, Department of Energy, Washington DC, USA., Sarazen ML; Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ, USA., Sholl DS; Oak Ridge National Laboratory, Oak Ridge, TN, USA., Smith EA; Ames National Laboratory, Ames, IA, USA.; Department of Chemistry, Iowa State University, Ames, IA, USA., Stevens MB; SLAC National Accelerator Laboratory, Menlo Park, CA, USA., Surendranath Y; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Tassone CJ; SLAC National Accelerator Laboratory, Menlo Park, CA, USA., Tran B; Pacific Northwest National Laboratory, Richland, WA, USA., Tumas W; National Renewable Energy Laboratory, Golden, CO, USA., Walton KS; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA.

Publikováno v: Nature reviews. Chemistry [Nat Rev Chem] 2024 May; Vol. 8 (5), pp. 376-400. Date of Electronic Publication: 2024 May 01.

Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells.

Autor: Walter K; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Rodriguez-Aznar E; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Ferreira MSV; Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, University Hospital of the RWTH Aachen, 52062 Aachen, Germany., Frappart PO; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany.; Institute of Toxicology, University Medical Centre of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Dittrich T; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Tiwary K; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Meessen S; Department of Urology, Ulm University, 89081 Ulm, Germany., Lerma L; Department of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid (UAM), 28049 Madrid, Spain., Daiss N; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Schulte LA; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Najafova Z; Department of Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany., Arnold F; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Usachov V; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Azoitei N; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Erkan M; Department of Surgery, Koç University School of Medicine, Istanbul 34450, Turkey.; Research Center for Translational Medicine, Koç University, Istanbul 34450, Turkey., Lechel A; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Brümmendorf TH; Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, University Hospital of the RWTH Aachen, 52062 Aachen, Germany., Seufferlein T; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Kleger A; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany., Tabarés E; Department of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid (UAM), 28049 Madrid, Spain., Günes C; Department of Urology, Ulm University, 89081 Ulm, Germany., Johnsen SA; Gene Regulatory Mechanisms and Molecular Epigenetics Lab, Gastroenterology Research, Mayo Clinic, Rochester, MN 55905, USA., Beier F; Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, University Hospital of the RWTH Aachen, 52062 Aachen, Germany., Sainz B Jr; Department of Biochemistry, Universidad Autónoma de Madrid (UAM), 28049 Madrid, Spain.; Department of Cancer Biology, Instituto de Investigaciones Biomédicas 'Alberto Sols' (IIBM), CSIC-UAM, 28049 Madrid, Spain.; Chronic Diseases and Cancer, Area 3-Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28049 Madrid, Spain., Hermann PC; Department of Internal Medicine I, University Medical Centre Ulm, 89081 Ulm, Germany.

Publikováno v: Cancers [Cancers (Basel)] 2021 Jun 23; Vol. 13 (13). Date of Electronic Publication: 2021 Jun 23.

Ustekinumab Inhibits T Follicular Helper Cell Differentiation in Patients With Crohn's Disease.

Autor: Globig AM; Department of Medicine II, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Berta-Ottenstein-Programme, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Sommer NP; Department of Medicine II, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Wild K; Department of Medicine II, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schardey J; Department of Medicine II, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Zoldan K; Department of Medicine II, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Thomann AK; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Schulte LA; Department of Medicine I, University Hospital Ulm, Ulm, Germany., Schreiner R; Medical Care Center Dr. Limbach and Colleagues, Heidelberg, Germany., Reindl W; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Klaus J; Department of Medicine I, University Hospital Ulm, Ulm, Germany., Schempp CM; Department of Dermatology and Venerology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Hofmann M; Department of Medicine II, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Thimme R; Department of Medicine II, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Boettler T; Department of Medicine II, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Hasselblatt P; Department of Medicine II, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address: peter.hasselblatt@uniklinik-freiburg.de.

Publikováno v: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2021; Vol. 11 (1), pp. 1-12. Date of Electronic Publication: 2020 Jul 15.

Ustekinumab serum concentrations are associated with clinical outcomes in Crohn's disease - a regional multi-center pilot study.

Autor: Thomann AK; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Schulte LA; Department of Medicine I, University Hospital Ulm, Ulm, Germany., Globig AM; Department of Medicine II, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany., Hoffmann P; Department of Gastroenterology and Hepatology, University Hospital Heidelberg, Heidelberg, Germany., Klag T; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany., Itzel T; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Teufel A; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Schreiner R; Medical Care Center Dr. Limbach and Colleagues, Heidelberg, Germany., Scheffe N; Medical Care Center Dr. Limbach and Colleagues, Heidelberg, Germany., Ebert MP; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Wehkamp J; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany., Gauss A; Department of Gastroenterology and Hepatology, University Hospital Heidelberg, Heidelberg, Germany., Hasselblatt P; Department of Medicine II, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany., Klaus J; Department of Medicine I, University Hospital Ulm, Ulm, Germany., Reindl W; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Publikováno v: Zeitschrift fur Gastroenterologie [Z Gastroenterol] 2020 May; Vol. 58 (5), pp. 439-444. Date of Electronic Publication: 2020 Feb 11.