Zobrazeno 1 - 10
of 313
pro vyhledávání: '"LA Harker"'
Publikováno v:
Blood. 77:1006-1012
To determine the role of thrombin in high blood flow, platelet- dependent thrombotic and hemostatic processes we measured the relative antithrombotic and antihemostatic effects in baboons of hirudin, a highly potent and specific antithrombin, and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e64916bbbd7b37271961c60e4a980aa8
https://doi.org/10.1182/blood.v77.5.1006.bloodjournal7751006
https://doi.org/10.1182/blood.v77.5.1006.bloodjournal7751006
Publikováno v:
Blood. 87(5)
The primary physiologic regulator of platelet production, Mpl ligand, has recently been cloned and characterized. To define the regulatory role of Mpl ligand on platelet production and function we measured the effects of a recombinant truncated human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6ee99877a6eb1f34f74107698a55db
https://pubmed.ncbi.nlm.nih.gov/8634430
https://pubmed.ncbi.nlm.nih.gov/8634430
Publikováno v:
Blood. 83(11)
The relative antithrombotic effectiveness of targeting glycoprotein (GP) Ib-dependent versus GPIIb-IIIa-dependent platelet interactions has been determined in baboons by measuring thrombus formation after infusing comparable antihemostatic doses of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72d55ecd0b1cdc9d7dfd1a09db0d142
https://pubmed.ncbi.nlm.nih.gov/8193356
https://pubmed.ncbi.nlm.nih.gov/8193356
Publikováno v:
Blood. 77(8)
In vivo complex formation of activated protein C with protein C inhibitor (APC-PCI) and with alpha 1-antitrypsin (APC-alpha 1AT) following infusion of 0.25 or 1.0 mg APC/kg in 1 hour into baboons was studied using immunoblotting and sandwich enzyme-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76525b180489a446b8705d978973ca54
https://pubmed.ncbi.nlm.nih.gov/1849759
https://pubmed.ncbi.nlm.nih.gov/1849759
Publikováno v:
British Journal of Clinical Pharmacology. 15:57S-60S
1 The thromboxane A2 synthetase inhibitor dazoxiben (UK 37248) was given orally to normal male baboons to determine its effect on platelet function in forming haemostatic plugs, and its capacity to prevent arteriovenous shunt and vascular graft throm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ab820cbe6621ff9aeacb6f1abb56b8
https://doi.org/10.1111/j.1365-2125.1983.tb02108.x
https://doi.org/10.1111/j.1365-2125.1983.tb02108.x
Autor:
LA Harker
Publikováno v:
American Journal of Physiology-Legacy Content. 218:1376-1380
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96579d525d397e6f6490f82adb202abf
https://doi.org/10.1152/ajplegacy.1970.218.5.1376
https://doi.org/10.1152/ajplegacy.1970.218.5.1376
Publikováno v:
Blood. 54(1)
Characteristics of murine megakaryocytic colonies and their progenitor cells (CFU-m) were studied in vitro in agar gel. Colony growth required the presence of poke-weed-mitogen-stimulated spleen-conditioned medium. The number of colonies formed was l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2349375a3e408e0cb3296b186c8aded1
https://pubmed.ncbi.nlm.nih.gov/444664
https://pubmed.ncbi.nlm.nih.gov/444664
Publikováno v:
Blood. 73(3)
The in vivo antithrombotic properties of human plasma activated protein C (APC), a natural anticoagulant enzyme, were investigated in a baboon model of thrombus formation on prosthetic vascular grafts. Infusion of 0.25 to 1.1 mg/kg/h purified, human,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba5b70f52f153ee68ef233a9099e2f1
https://pubmed.ncbi.nlm.nih.gov/2917194
https://pubmed.ncbi.nlm.nih.gov/2917194
Publikováno v:
Blood. 71(5)
Megakaryocytes from normal routine human bone marrow aspirates were analyzed by flow cytometry for size, fine cell structure and granularity, membrane expression of glycoprotein (GP) IIb/IIIa and ploidy. Marrow cells were initially enriched for megak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7f48c77373b748bd5002feb327574b
https://pubmed.ncbi.nlm.nih.gov/3359043
https://pubmed.ncbi.nlm.nih.gov/3359043
Publikováno v:
Blood. 73(6)
Fibrinolytic activity was found to be associated with sonicated platelet membranes after separation from cytosol by differential centrifugation. This fibrinolytic activity was attributed to the presence of a plasminogen activator, which was immunoche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f9ae227e14568951e8cda5b95c5e34
https://pubmed.ncbi.nlm.nih.gov/2653456
https://pubmed.ncbi.nlm.nih.gov/2653456