Zobrazeno 1 - 10
of 342
pro vyhledávání: '"L.Y. Dirix"'
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 2 (2010)
Vast preclinical and clinical evidence has made angiogenesis one of the hallmarks of cancer. In many human tumours, vascular endothelial growth factor (VEGF) has been identified as the crucial mediator of this process. Initial studies suggested that
Externí odkaz:
https://doaj.org/article/538e723cca8c4e658cd0283c5383e4e4
Autor:
K. Van Baelen, H.L. Nguyen, F. Richard, G. Zels, M.M. Karsten, G. Nader Marta, P. Vermeulen, L.Y. Dirix, H. Wuyts, A.D. Dordevic, E. de Azambuja, D. Larsimont, M. Maetens, E. Biganzoli, H. Wildiers, A. Smeets, I. Nevelsteen, P. Neven, G. Floris, C. Desmedt
Publikováno v:
ESMO Open. 8:101276
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28318b2aefbb82637df50f7b64063c85
https://doi.org/10.1016/j.esmoop.2023.101276
https://doi.org/10.1016/j.esmoop.2023.101276
Autor:
J.M. Bartlett, K. Xu, J. Wong, G. Pond, Y. Zhang, M. Spears, R. Salunga, E. Mallon, K.J. Taylor, A. Hasenburg, C. Markopoulos, L.Y. Dirix, C. Seynaeve, C. van de Velde, D. Rea, C.A. Schnabel, K. Treuner, J. Bayani
Publikováno v:
Annals of Oncology. 33:S602
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0414c221b0d9e7cb7bc634296f55316
https://doi.org/10.1016/j.annonc.2022.07.173
https://doi.org/10.1016/j.annonc.2022.07.173
Autor:
Annette Hasenburg, X Zhang, Arun Seth, Cheryl Crozier, M Larivière, Seth Sadis, Jms Bartlett, Dirk G. Kieback, JM Smith, L.Y. Dirix, Jane Bayani, Mary Anne Quintayo, D.W. Rea, Martin J. Yaffe, Harriet Feilotter, Yutaka Amemiya, C. Markopoulos
Publikováno v:
Cancer Research. 78:P2-09
Large-scale sequencing initiatives have revealed a wealth of common and novel variants as well as copy-number aberrations, across different malignancies. This growing list of variants/aberrations can sometimes be matched to specific therapeutics. Suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ac823468c77308e86022d5b22d8a9db
https://doi.org/10.1158/1538-7445.sabcs17-p2-09-17
https://doi.org/10.1158/1538-7445.sabcs17-p2-09-17
Autor:
Jms Bartlett, L.Y. Dirix, T Piper, Annette Hasenburg, Dirk G. Kieback, Carine Seynaeve, Elizabeth Mallon, Cjh Can de Velde, D.W. Rea, Paul C. Boutros, CQ Yao, Elizabeth N. Kornaga, C. Markopoulos, Jane Bayani
Publikováno v:
Cancer Research. 78:P1-06
Multiparametric assays for risk are increasingly used in the management of node-negative and node-positive hormone receptor-positive invasive breast cancer. Data from multiple sources suggests different tests may provide different risk estimates at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78f58fb0573cb5795755af4c77059c15
https://doi.org/10.1158/1538-7445.sabcs17-p1-06-02
https://doi.org/10.1158/1538-7445.sabcs17-p1-06-02
Autor:
Cjh van de Velde, Carine Seynaeve, L.Y. Dirix, D.W. Rea, Jane Bayani, C. Markopoulos, T Piper, James D. Thomas, Elizabeth Mallon, Annette Hasenburg, Jms Bartlett, Dirk G. Kieback
Publikováno v:
Cancer Research. 78:P1-06
Histological grade remains an independent predictor of outcome for invasive breast cancer. The internationally accepted standard grading system is the Elston and Ellis grading system based on a local hospital (Nottingham) cohort treated between 1951-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0735e955d1721ec796fe98c3a46d8918
https://doi.org/10.1158/1538-7445.sabcs17-p1-06-04
https://doi.org/10.1158/1538-7445.sabcs17-p1-06-04
Autor:
Quang M. Trinh, Gun Ho Jang, CQ Yao, Melanie Spears, Jms Bartlett, L.Y. Dirix, D.W. Rea, C. Markopoulos, Irina Kalatskaya, Julie Livingstone, Dirk G. Kieback, Elizabeth N. Kornaga, Paul C. Boutros, Lincoln Stein, Cheryl Crozier, Jane Bayani, Annette Hasenburg
Publikováno v:
Cancer Research. 78:PD4-11
Hormone receptor positive breast cancer remains an ongoing therapeutic challenge. Despite optimal anti-endocrine therapies, most breast cancer deaths follow a diagnosis of early luminal cancer. Data describing molecular events in breast cancer has ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c94538ad83442360352a3215f528d18
https://doi.org/10.1158/1538-7445.sabcs17-pd4-11
https://doi.org/10.1158/1538-7445.sabcs17-pd4-11
Autor:
Mark M. Kockx, S. Van Laere, Yannick Waumans, C. Rypens, Koen M. Marien, C. Van Berckelaer, C Colpaert, P. van Dam, L.Y. Dirix, Peter B. Vermeulen
Publikováno v:
Cancer Research. 79:P4-06
Introduction The mechanisms contributing to the aggressive biology of inflammatory breast cancer (IBC) are still under investigation. Our lab reported a 79-gene signature that is shaped by specific immune response programs and discriminates between I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37eda4dd685b36ffe3c4e0c9824d9f2e
https://doi.org/10.1158/1538-7445.sabcs18-p4-06-08
https://doi.org/10.1158/1538-7445.sabcs18-p4-06-08
Publikováno v:
Cancer Research. 77:P1-06
Background A growing understanding of the molecular biology of cancer and the identification of specific aberrations driving cancer evolution have led to the development of various targeted agents. Tumors can exhibit significant heterogeneity and thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::265fc490309992d8c4a3f9f718df65a7
https://doi.org/10.1158/1538-7445.sabcs16-p1-06-01
https://doi.org/10.1158/1538-7445.sabcs16-p1-06-01
Autor:
M-C. Liu, Joseph A. Sparano, M.M. Moezi, S-B Kim, Elizabeth Tan-Chiu, Mark Kozloff, V. McNally, L.Y. Dirix, Jung Ho Sohn, B. Simmons, Matthew Wongchenko, José A. García-Sáenz, Marleen Borms, N. Xu, Adam Brufsky, David Miles, Thierry Velu
Publikováno v:
Cancer Research. 77:P4-22
Resistance to standard taxane-based chemotherapy is common in triple-negative breast cancer (TNBC). Mutations and gene amplifications in the MAPK pathway that upregulate MAPK signaling are present in many TNBC tumors. Upregulation of the MAPK signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1c433dbf60a8bdd2822c01f1c4f2bb6
https://doi.org/10.1158/1538-7445.sabcs16-p4-22-22
https://doi.org/10.1158/1538-7445.sabcs16-p4-22-22